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FMOC-O-tert-Butyl-L-serine

Product Name
FMOC-O-tert-Butyl-L-serine
CAS No.
71989-33-8
Chemical Name
FMOC-O-tert-Butyl-L-serine
Synonyms
FMOC-SER(TBU)-OH;FMOC-SER(TBU);FMOC-L-SER(TBU)-OH;FMOC-SER(BUT);Fomc-Ser(tBu)-OH;FMOC-L-Ser(tBu)-OH 98%;Fomc-Ser(t;Fmoc-Ser(OBut);FMOC-L-SER(T-BU);FMOC-SER(BUT)-OH
CBNumber
CB4315210
Molecular Formula
C22H25NO5
Formula Weight
383.44
MOL File
71989-33-8.mol
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FMOC-O-tert-Butyl-L-serine Property

Melting point:
130.5-135.5 °C(lit.)
alpha 
25 º (c=1,EtOAc 24 ºC)
Boiling point:
510.36°C (rough estimate)
Density 
1.2369 (rough estimate)
refractive index 
24 ° (C=1, AcOEt)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.44±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
optical activity
[α]20/D +25.5±1°, c = 1% in ethyl acetate
BRN 
3632013
InChI
InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChIKey
REITVGIIZHFVGU-IBGZPJMESA-N
SMILES
C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference
71989-33-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36/37/39-27-26
WGK Germany 
3
HS Code 
29242990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52019
Product name
Fmoc-Ser(tBu)-OH
Purity
Novabiochem?
Packaging
25g
Price
$90.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52019
Product name
Fmoc-Ser(tBu)-OH
Purity
Novabiochem?
Packaging
100g
Price
$326
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52019
Product name
Fmoc-Ser(tBu)-OH
Purity
Novabiochem?
Packaging
250g
Price
$687
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52019
Product name
Fmoc-Ser(tBu)-OH
Purity
Novabiochem?
Packaging
1kg
Price
$2360
Updated
2024/03/01
Sigma-Aldrich
Product number
47619
Product name
Fmoc-Ser(tBu)-OH
Purity
≥98.0% (HPLC)
Packaging
10g
Price
$67.9
Updated
2024/03/01
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FMOC-O-tert-Butyl-L-serine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:

  • Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
  • Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
  • Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.

General Description

The product number for this product was previously 04-12-1033.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

FMOC-O-tert-Butyl-L-serine Preparation Products And Raw materials

Raw materials

Fluorene 1,4-Dioxane H-SER(TBU)-OH

Preparation Products

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FMOC-O-tert-Butyl-L-serine Suppliers

Americas 1 Belgium 1 Canada 2 China 358 Europe 5 France 2 Germany 7 India 15 Israel 1 Japan 8 Poland 1 Switzerland 7 United Kingdom 17 United States 68 Global 493
Christof Senn Laboratories AG
Tel
--
Fax
--
Email
christof.senn@cslabs.ch
Country
Switzerland
ProdList
502
Advantage
58
Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
ASCHEM GmbH
Tel
--
Fax
--
Email
info@aschem.ch
Country
Switzerland
ProdList
897
Advantage
58
Bachem AG
Tel
--
Fax
--
Email
sales.ch@bachem.com
Country
Switzerland
ProdList
434
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Senn Chemicals AG
Tel
--
Fax
--
Email
swiss@sennchem.com
Country
Switzerland
ProdList
3143
Advantage
71
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74
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View Lastest Price from FMOC-O-tert-Butyl-L-serine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Ser(tBu)-OH 71989-33-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-12-07
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Fmoc-Ser(tBu)-OH 71989-33-8
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kgs
Release date
2021-09-26
Chengdu Baishixing Science and Technology Industry Co.,Ltd
Product
Fmoc-Ser(tbu)-OH 71989-33-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2T/month
Release date
2023-07-21

71989-33-8, FMOC-O-tert-Butyl-L-serineRelated Search:

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  • (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(tert-butoxy)propanoic acid
  • L-Serine-UL-13C3, 15N-N-FMOC
  • L-Serine, O-(1,1-dimethylethyl)-N-(9H-fluoren-9-ylmethoxy)carbonyl-
  • N-FMOC-O-TERT-BUTYL-L-SERINE
  • N-FMOC-SER(T-BU)-OH
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Ser(tBu)-OH
  • Fmoc-Ser(OBut)
  • Fomc-Ser(t
  • Fomc-Ser(tBu)-OH
  • NALPHA-9-Fluorenylmethoxycarbonyl-O-tert-butyl-L-serine
  • FMOC-O-TERT-BUTYL-L-SERINE (FMOC-L-SER(TBU)-OH)
  • N-(9-FLUORENYLMETHOXYCARBONYL)-2-TERT-BUTYL-L-SERINE
  • L-SERINE-N-FMOC, O-TERT-BUTYL ETHER (1-13C)
  • L-SERINE-N-FMOC, O-TERT-BUTYL ETHER (13C3,15N)
  • Fmoc-O-tert-butyl-L-serine≥ 99.7% (HPLC, Chiral purity)
  • N-FMOC-O-T-BUTYL-L-SERINE
  • N-FMOC-T-BUTYL-L-SER
  • N-ALPHA-FMOC-O-TERT-BUTYL-L-SERINE
  • N-ALPHA-FMOC-O-T-BUTYL-L-SERINE
  • N-9-FLUORENYLMETHYLOXYCARBONYL-O-TERT-BUTYL-L-SERINE
  • N-9-FLUORENYLMETHYLOXYCARBONYL-O-T-BUTYL-L-SERINE
  • N-(9-FLUORENYL METHOXY CARBONYL)-O-TERT-BUTYL-L-SERINE
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TERT-BUTYL-L-SERINE
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-T-BUTYL-L-SERINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-T-BUTYL-L-SERINE
  • FMOC-L-SERINE(O-T-BUTYL)
  • FMOC-L-SERINE (TBU)
  • FMOC-L-SER(O-T-BUTYL)
  • FMOC-L-SER(T-BU)
  • FMOC-L-SER(TBU)-OH
  • FMOC-O-T-BUTYL-L-SERINE
  • FMOC-O-TERT-BUTYL-L-SERINE
  • FMOC-SER(TBU)
  • FMOC-SER(TBU)-OH
  • FMOC-SER(BUT)
  • FMOC-SERINE(TBU)-OH