ChemicalBook > CAS DataBase List > PYRIDINE-2-THIOAMIDE

PYRIDINE-2-THIOAMIDE

Product Name: PYRIDINE-2-THIOAMIDE
CAS No.: 5346-38-3
Chemical Name: PYRIDINE-2-THIOAMIDE
Synonyms: 2-Pyridylthioamide;PYRIDINE-2-CARBOTHIOAMIDE;thio-picolinamid;Thiopicolinamide;picolinothioamide;2-thiopicolinamide;CHEMBRDG-BB 4017339;2-Pyridinethioamide;PYRIDINE-2-THIOAMIDE;picolinicacidthioamide
CBNumber: CB3393268
Molecular Formula: C6H6N2S
Formula Weight: 138.19
MOL File: 5346-38-3.mol

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PYRIDINE-2-THIOAMIDE Property

Melting point:: 134-138 °C
Boiling point:: 278.9±32.0 °C(Predicted)
Density: 1.265±0.06 g/cm3(Predicted)
Flash point:: 160 °C
storage temp.: Inert atmosphere,Room Temperature
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
pka: 11.98±0.29(Predicted)
form: Crystalline Powder
color: Yellow
InChI: InChI=1S/C6H6N2S/c7-6(9)5-3-1-2-4-8-5/h1-4H,(H2,7,9)
InChIKey: HYKQYVSNFPWGKQ-UHFFFAOYSA-N
SMILES: C1(C(N)=S)=NC=CC=C1
CAS DataBase Reference: 5346-38-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38-43-41-37/38-22
Safety Statements: 26-36/37/39
WGK Germany: 3
RTECS: TJ4305500
HazardClass: IRRITANT
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 699047
Product name: 2-Pyridinethioamide
Purity: 97%
Packaging: 5g
Price: $25.5
Updated: 2025/07/31

TCI Chemical

Product number: T2618
Product name: Thiopicolinamide
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $24
Updated: 2025/07/31

TCI Chemical

Product number: T2618
Product name: Thiopicolinamide
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $68
Updated: 2025/07/31

Cayman Chemical

Product number: 13043
Product name: 2-Pyridylthioamide
Purity: ≥98%
Packaging: 1g
Price: $11
Updated: 2024/03/01

Cayman Chemical

Product number: 13043
Product name: 2-Pyridylthioamide
Purity: ≥98%
Packaging: 5g
Price: $40
Updated: 2024/03/01

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PYRIDINE-2-THIOAMIDE Chemical Properties,Usage,Production

Uses

2-Pyridinecarbothioamide is a building block, that can be used for synthesis of Zn2+ responsive fluorescent probe[1].

Synthesis

100-70-9

5346-38-3

General Steps: a. Diphosphorus tetrasulfide (115 g, 0.5 mol) was slowly added to 250 mL of 20% ammonia in methanol solution containing 4-cyanopyridine (52 g, 0.5 mol) under vigorous stirring, ensuring that the temperature of the reaction mixture was maintained below 35-40°C. b. The reaction mixture was allowed to run for 12 hours at room temperature. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, 150 mL of water was added and the mixture was heated to 70-75 °C via a water bath until gas release ceased. After cooling to room temperature, the precipitate was collected by filtration, washed well with water and then dried. The product pyridine-2-carboxy sulfate amine was obtained in 89% yield (61.8 g) with an Rf value of 0.45 and a melting point of 137 °C (literature value: 136-137 °C). Elemental analysis result (%): C 52.09, H 4.31, N 20.30, S 23.30; theoretical value (C6H6N2S): C 52.15, H 4.38, N 20.27, S 23.20.

References

[1] Watanabe Y, et al. A zinc-responsive fluorophore based on 5′-(p-hydroxyphenyl)-pyridylthiazole[J]. Materials Chemistry Frontiers, 2020, 4(3): 899-904.

PYRIDINE-2-THIOAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PYRIDINE-2-THIOAMIDE manufacturers

Dideu Industries Group Limited

Product: PYRIDINE-2-THIOAMIDE 5346-38-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-27

Career Henan Chemical Co

Product: PYRIDINE-2-THIOAMIDE 5346-38-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-07-11

5346-38-3, PYRIDINE-2-THIOAMIDERelated Search:

2-Pyridinesulfonamide(6CI,7CI,9CI) Pyridine trifluoroacetate 2,3,5,6-Tetraaminopyridine trihydrochloride 4-Pyridinesulfonamide(6CI,9CI) 2,6-Pyridinedicarbonitrile Pyridine hydrochloride dimethyl pyridine-3,5-dicarboxylate METHYL ISONICOTINATE Pyridine-N-oxide 2-Pyridinecarbaldehyde oxime PYRIDINE-2-SULFONYL FLUORIDE PYRIDINE-3,4-DICARBOXYLIC ANHYDRIDE PYRIDINE-3-THIOAMIDE PYRIDINE-4-THIOAMIDE PYRIDINE-2-THIOAMIDE 5-(TRIFLUOROMETHYL)PYRIDINE-2-THIOCARBOXAMIDE 2,2'-bipyridyl-6-carbothioamide 4-METHYLPYRIDINE-2-CARBOTHIOAMIDE

PYRIDINE-2-THIOAMIDE

PYRIDINE-2-CARBOTHIOIC ACID AMIDE

2-PYRIDINETHIOCARBOXAMIDE

CHEMBRDG-BB 4017339

2-pyridinecarbothioamide

2-thiocarbamoylpyridine

2-thiopicolinamide

picolinicacidthioamide

picolinothioamide

thio-2-pyridinecarboxamide

thio-picolinamid

PYRIDINE-2-CARBOTHIOAMIDE

2-Pyridinethioamide

2-Pyridylthioamide, Pyridine-2-carbothioamide

Thiopicolinamide

2-Pyridylthioamide

2-Pyridylthiocarboxamide

pyridine-2-thiocarboxamide

pyridine-2-carbothioamide(SALTDATA: FREE)

3-[oxo(pyridin-4-yl)methyl]benzenesulfonyl chloride

Pyridinecarbothioamide

PYRIDINE-2-THIOAMIDE ISO 9001：2015 REACH

2-Pyridinecarbothioamide (9CI, ACI)

Pyridin-2-carbothioamide

5346-38-3

5346-28-3

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Pyridines