dimethyl pyridine-3,5-dicarboxylate
- Product Name
- dimethyl pyridine-3,5-dicarboxylate
- CAS No.
- 4591-55-3
- Chemical Name
- dimethyl pyridine-3,5-dicarboxylate
- Synonyms
- 5-dicarboxylate;dimethyl pyridine-3;pyridine-3,5-dicarboxyL;Dimethyl 3,5-Pyridinedicarboxylate;dimethyl pyridine-3,5-dicarboxylate;3,5-Pyridinedicarboxylic acid dimethyl ester;3,5-Pyridinedicarboxylicacid, 3,5-diMethyl ester;dimethyl pyridine-3,5-dicarboxylate hydrochloride
- CBNumber
- CB4901677
- Molecular Formula
- C9H9NO4
- Formula Weight
- 195.17
- MOL File
- 4591-55-3.mol
dimethyl pyridine-3,5-dicarboxylate Property
- Melting point:
- 84-85 °C
- Boiling point:
- 267.6±20.0 °C(Predicted)
- Density
- 1.231±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform, Dichloromethane, Methanol
- form
- Solid
- pka
- 1.16±0.20(Predicted)
- color
- Pale Yellow
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D5364
- Product name
- Dimethyl 3,5-Pyridinedicarboxylate
- Packaging
- 5G
- Price
- $85
- Updated
- 2025/07/31
- Product number
- D5364
- Product name
- Dimethyl 3,5-Pyridinedicarboxylate
- Packaging
- 25G
- Price
- $294
- Updated
- 2025/07/31
- Product number
- D479055
- Product name
- Dimethyl 3,5-Pyridinedicarboxylate
- Packaging
- 10g
- Price
- $1055
- Updated
- 2021/12/16
- Product number
- W6383
- Product name
- Dimethylpyridine-3,5-dicarboxylate
- Packaging
- 100g
- Price
- $1341
- Updated
- 2021/12/16
- Product number
- FD139443
- Product name
- Dimethyl pyridine-3,5-dicarboxylate
- Packaging
- 25g
- Price
- $393
- Updated
- 2021/12/16
dimethyl pyridine-3,5-dicarboxylate Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Uses
Dimethyl 3,5-Pyridinedicarboxylate (cas# 4591-55-3) is a compound useful in organic synthesis.
Synthesis
67-56-1
499-81-0
4591-55-3
The general procedure for the synthesis of methyl 3,5-pyridinedicarboxylate from methanol and 3,5-pyridinedicarboxylic acid is as follows: 3,5-pyridinedicarboxylic acid (5.00 g, 29.92 mmol) was dissolved in methanol (100 ml), concentrated sulfuric acid (2 ml) was added slowly as a catalyst, and the reaction mixture was stirred for 18 hrs under reflux conditions. After completion of the reaction, the solvent methanol was removed by distillation under reduced pressure. Subsequently, the reaction mixture was neutralized with aqueous sodium bicarbonate and separated by extraction with dichloromethane. The dichloromethane layer was collected and washed with saturated aqueous sodium chloride solution to remove residual water-soluble impurities. Eventually, the dichloromethane layer was concentrated by decompression to give the white solid product methyl 3,5-pyridinedicarboxylate (5.5 g, 94% yield).
References
[1] ACS Medicinal Chemistry Letters, 2016, vol. 7, # 10, p. 933 - 938
[2] Patent: KR2018/9249, 2018, A. Location in patent: Paragraph 0250; 0251
[3] Angewandte Chemie - International Edition, 2004, vol. 43, # 30, p. 3914 - 3918
[4] Bulletin of the Korean Chemical Society, 2015, vol. 36, # 9, p. 2397 - 2400
[5] Life Sciences, 2005, vol. 78, # 5, p. 495 - 505
dimethyl pyridine-3,5-dicarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from dimethyl pyridine-3,5-dicarboxylate manufacturers
- Product
- dimethyl pyridine-3,5-dicarboxylate 4591-55-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 500kg/month
- Release date
- 2019-08-01