ChemicalBook > CAS DataBase List > dimethyl pyridine-3,5-dicarboxylate

dimethyl pyridine-3,5-dicarboxylate

Product Name
dimethyl pyridine-3,5-dicarboxylate
CAS No.
4591-55-3
Chemical Name
dimethyl pyridine-3,5-dicarboxylate
Synonyms
5-dicarboxylate;dimethyl pyridine-3;pyridine-3,5-dicarboxyL;Dimethyl 3,5-Pyridinedicarboxylate;dimethyl pyridine-3,5-dicarboxylate;3,5-Pyridinedicarboxylic acid dimethyl ester;3,5-Pyridinedicarboxylicacid, 3,5-diMethyl ester;dimethyl pyridine-3,5-dicarboxylate hydrochloride
CBNumber
CB4901677
Molecular Formula
C9H9NO4
Formula Weight
195.17
MOL File
4591-55-3.mol
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dimethyl pyridine-3,5-dicarboxylate Property

Melting point:
84-85 °C
Boiling point:
267.6±20.0 °C(Predicted)
Density 
1.231±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform, Dichloromethane, Methanol
form 
Solid
pka
1.16±0.20(Predicted)
color 
Pale Yellow
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D5364
Product name
Dimethyl 3,5-Pyridinedicarboxylate
Packaging
5G
Price
$85
Updated
2025/07/31
TCI Chemical
Product number
D5364
Product name
Dimethyl 3,5-Pyridinedicarboxylate
Packaging
25G
Price
$294
Updated
2025/07/31
TRC
Product number
D479055
Product name
Dimethyl 3,5-Pyridinedicarboxylate
Packaging
10g
Price
$1055
Updated
2021/12/16
AK Scientific
Product number
W6383
Product name
Dimethylpyridine-3,5-dicarboxylate
Packaging
100g
Price
$1341
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD139443
Product name
Dimethyl pyridine-3,5-dicarboxylate
Packaging
25g
Price
$393
Updated
2021/12/16
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dimethyl pyridine-3,5-dicarboxylate Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

Dimethyl 3,5-Pyridinedicarboxylate (cas# 4591-55-3) is a compound useful in organic synthesis.

Synthesis

67-56-1

499-81-0

4591-55-3

The general procedure for the synthesis of methyl 3,5-pyridinedicarboxylate from methanol and 3,5-pyridinedicarboxylic acid is as follows: 3,5-pyridinedicarboxylic acid (5.00 g, 29.92 mmol) was dissolved in methanol (100 ml), concentrated sulfuric acid (2 ml) was added slowly as a catalyst, and the reaction mixture was stirred for 18 hrs under reflux conditions. After completion of the reaction, the solvent methanol was removed by distillation under reduced pressure. Subsequently, the reaction mixture was neutralized with aqueous sodium bicarbonate and separated by extraction with dichloromethane. The dichloromethane layer was collected and washed with saturated aqueous sodium chloride solution to remove residual water-soluble impurities. Eventually, the dichloromethane layer was concentrated by decompression to give the white solid product methyl 3,5-pyridinedicarboxylate (5.5 g, 94% yield).

References

[1] ACS Medicinal Chemistry Letters, 2016, vol. 7, # 10, p. 933 - 938
[2] Patent: KR2018/9249, 2018, A. Location in patent: Paragraph 0250; 0251
[3] Angewandte Chemie - International Edition, 2004, vol. 43, # 30, p. 3914 - 3918
[4] Bulletin of the Korean Chemical Society, 2015, vol. 36, # 9, p. 2397 - 2400
[5] Life Sciences, 2005, vol. 78, # 5, p. 495 - 505

dimethyl pyridine-3,5-dicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from dimethyl pyridine-3,5-dicarboxylate manufacturers

Career Henan Chemical Co
Product
dimethyl pyridine-3,5-dicarboxylate 4591-55-3
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
500kg/month
Release date
2019-08-01

4591-55-3, dimethyl pyridine-3,5-dicarboxylateRelated Search:

Pyridine hydrochloride 2,6-Pyridinedicarbonitrile 4-Pyridinesulfonamide(6CI,9CI) 2,3,5,6-Tetraaminopyridine trihydrochloride Pyridine trifluoroacetate PYRIDINE-2-THIOAMIDE 2-Pyridinesulfonamide(6CI,7CI,9CI) METHYL ISONICOTINATE Pyridine-N-oxide 2-Pyridinecarbaldehyde oxime PYRIDINE-2-SULFONYL FLUORIDE PYRIDINE-3,4-DICARBOXYLIC ANHYDRIDE DIETHYL 2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE Diethyl pyridine-3,5-dicarboxylate dimethyl pyridine-3,5-dicarboxylate DIMETHYL 4-(4-METHOXYPHENYL)-2,6-DIMETHYLPYRIDINE-3,5-DICARBOXYLATE Dehydronitrendipine OXIDIZED NIFEDIPINE

  • 3,5-Pyridinedicarboxylicacid, 3,5-diMethyl ester
  • dimethyl pyridine-3,5-dicarboxylate
  • 3,5-Pyridinedicarboxylic acid dimethyl ester
  • Dimethyl 3,5-Pyridinedicarboxylate
  • pyridine-3,5-dicarboxyL
  • 5-dicarboxylate
  • dimethyl pyridine-3
  • dimethyl pyridine-3,5-dicarboxylate hydrochloride
  • 4591-55-3
  • Heterocycle-Pyridine series
  • Aromatics
  • Heterocycles