4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE

Product Name: 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE
CAS No.: 162641-16-9
Chemical Name: 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE
Synonyms: CS-620;HQL-97;HQL-79;HQL 79;HQL79;4-benzhydryloxy-1-[3-(2H-tetrazol-5-yl)propyl]piperidine;1-(3-(1H-Tetrazol-5-yl)propyl)-4-(benzhydryloxy)piperidine;4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine;4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE;Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-
CBNumber: CB3399336
Molecular Formula: C22H27N5O
Formula Weight: 377.48
MOL File: 162641-16-9.mol

More

Less

4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE Property

Boiling point:: 553.6±60.0 °C(Predicted)
Density: 1.21
storage temp.: Store at RT
solubility: DMSO: soluble2mg/mL, clear (warmed)
form: powder
pka: 4.85±0.10(Predicted)
color: white to beige

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0857
Product name: HQL 79
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $97.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0857
Product name: HQL 79
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $478
Updated: 2024/03/01

Cayman Chemical

Product number: 10134
Product name: HQL 79
Purity: ≥98%
Packaging: 1mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 10134
Product name: HQL 79
Purity: ≥98%
Packaging: 5mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 10134
Product name: HQL 79
Purity: ≥98%
Packaging: 10mg
Price: $146
Updated: 2024/03/01

More

Less

4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE Chemical Properties,Usage,Production

Uses

HQL-79 is a selective PGE synthase inhibitor.

Biological Activity

HQL 79 is an orally active anti-allergic agent th at acts as an antagonist for histamine H1 receptors (H1R), eliciting anti-asthmatic effects. It interacts with prostaglandin (PG) D synthase (H-PGDS) in the catalytic region. It may be potential lead due to its H-PGDS inhibition to tre at allergies.', 'HQL-79 is a selective inhibtor of hematopoietic prostaglandin D (PGD) synthase, one of two synthases involved in the production of Prostaglandin D2 (PGD2) from arachidonic acid. PGD2 is a lipid signaling molecule, which activates two receptors, DP1 involved in centrally mediated processes such as sleep and pain and DP2 involved and inflammation. The two PGD synthases involved in its synthesis are lipocalin-type (L-PGDS) and hematopoietic (H-PDGS), which acts to form PGD2 in mast cells, Th2 cells, microglia, and other inflammatory cells/tissues. HQL-79 selectively inhibited the activity of recombinant H-PGDS with an IC50 of 6 μM and had almost no effect on COX-1, COX-2, m-PGES, or L-PGDS up to 300 μM. HQL-79 has anti-inflammatory activity in vitro and in vivo.

storage

Store at RT

4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE Suppliers

China 75 Switzerland 1 United Kingdom 3 United States 15 Global 94

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4674
Advantage: 55

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Jinan Mingya Medical Technology Co., Ltd.

Tel: 0531-85828981
Fax: +86-531-85806006
Email: 864598798@qq.com
Country: China
ProdList: 588
Advantage: 58

GIHI CHEMICALS CO.,LTD

Tel: 0086-571-86217390
Fax: 0086-571-86217391
Email: Sales@gihichem.com
Country: China
ProdList: 860
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

More

Less

View Lastest Price from 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE manufacturers

Career Henan Chemical Co

Product: 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE 162641-16-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-13

162641-16-9, 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINERelated Search:

(S)-(+)-Benzyl glycidyl ether Phenethyl alcohol Titanium tetrachloride potassium 2-hydroxy-4-methoxybenzoate p-Anisidine Guaiacol Diphenylphosphine oxide diphenylpyraline 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE 4-(DIPHENYLMETHOXY)PIPERIDINE

HQL-79

4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine

HQL-97

4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE

CS-620

HQL 79;HQL79

Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-

1-(3-(1H-Tetrazol-5-yl)propyl)-4-(benzhydryloxy)piperidine

4-benzhydryloxy-1-[3-(2H-tetrazol-5-yl)propyl]piperidine

162641-16-9

C22H27N5O