3-(3-(Trifluoromethyl)phenyl)propanal

Uses

Product Name: 3-(3-(Trifluoromethyl)phenyl)propanal
CAS No.: 21172-41-8
Chemical Name: 3-(3-(Trifluoromethyl)phenyl)propanal
Synonyms: 3-(3-(trifluoroMethyl)phenyl)propanal;Cinacalcet Impurity 54;3-(Trifluoromethyl)benzenepropanal;4-[3-(trifluoroMethyl)phenyl]butanal;Benzenepropanal, 3-(trifluoroMethyl)-;m-(Trifluoromethyl)hydrocinnamaldehyde;3-(trifluoroMethylphenyl)propionaldehyde;3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIOLDEHYDE;3-(3’-TRIFLUOROMETHYL PHENYL)PROPIONALDEHYDE;3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE
CBNumber: CB3420003
Molecular Formula: C10H9F3O
Formula Weight: 202.17
MOL File: 21172-41-8.mol

More

Less

3-(3-(Trifluoromethyl)phenyl)propanal Property

Boiling point:: 207.4±35.0 °C(Predicted)
Density: 1.192±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Soluble in Chloroform, Dichloromethane, Ethyl acetate
form: Oil
color: Clear colorless to pale yellow oily liquid
Stability:: Not very stable, new spot on TLC if kept at r.t. o/n.
InChI: InChI=1S/C10H9F3O/c11-10(12,13)9-5-1-3-8(7-9)4-2-6-14/h1,3,5-7H,2,4H2
InChIKey: APCCHYPQHODSBD-UHFFFAOYSA-N
SMILES: C1(CCC=O)=CC=CC(C(F)(F)F)=C1

More

Less

Safety

HS Code: 2912490090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TRC

Product number: T791100
Product name: 3-(Trifluoromethyl)benzenepropanal
Packaging: 100mg
Price: $110
Updated: 2021/12/16

Apolloscientific

Product number: PC57040
Product name: 3-[3-(Trifluoromethyl)phenyl]propanal
Packaging: 1g
Price: $155
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2815-3-48
Product name: 3-[3-(Trifluoromethyl)phenyl]propanal
Packaging: 1g
Price: $248
Updated: 2021/12/16

AK Scientific

Product number: J50338
Product name: 3-(Trifluoromethyl)benzenepropanal
Packaging: 25g
Price: $420
Updated: 2021/12/16

Matrix Scientific

Product number: 119343
Product name: 3-(3-(Trifluoromethyl)phenyl)propanal
Purity: 95+%
Packaging: 250mg
Price: $274
Updated: 2021/12/16

More

Less

3-(3-(Trifluoromethyl)phenyl)propanal Chemical Properties,Usage,Production

Uses

3-(Trifluoromethyl)benzenepropanal is a compound useful in organic synthesis.

Chemical Properties

Colourless Oil

Uses

3-(Trifluoromethyl)benzenepropanal (cas# 21172-41-8) is a compound useful in organic synthesis.

Synthesis

A solution of 3-(Trifluoromethyl) benzene propanol (1.0 g, 4.90 mmol) in dichloromethane (20 ml) is cooled in a water/ice bath, treated in succession with DMSO (770 mg, 9.80 mmol) and P2O5 (1.39 g, 9.80 mmol) and left under stirring for 30 minutes, while temperature raises to 20°C. The reaction mixture is then cooled in water/ice bath and triethylamine (2.4 ml, 17.15 mmol). The resulting solution is kept under stirring while the temperature raises to 20°C. After one hour, the mixture is treated with 5 per cent HCl, the phases are separated, and the organic one is further washed with 5 per cent HCl. The organic phase is then washed with brine, dried over Na2SO4, filtered and concentrated under reduced pressure to afford 0.99 g of the aldehyde of 3-(3-(Trifluoromethyl)phenyl)propanal in quantitative yield.

References

[1] Patent: EP2327684, 2011, A1. Location in patent: Page/Page column 6
[2] Patent: US2011/124917, 2011, A1. Location in patent: Page/Page column 3-4
[3] Journal of the Indian Chemical Society, 2013, vol. 90, # 8, p. 1259 - 1261
[4] Patent: WO2014/16847, 2014, A1. Location in patent: Page/Page column 6-7
[5] Tetrahedron Letters, 2004, vol. 45, # 45, p. 8355 - 8358

3-(3-(Trifluoromethyl)phenyl)propanal Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-(3-(Trifluoromethyl)phenyl)propanal Suppliers

Canada 1 China 156 Germany 1 India 9 South Korea 1 United Kingdom 1 United States 10 Global 179

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Scientia Pharmaceutical Technology Co., Ltd.

Tel: 21-21-54301573 13917723525
Fax: (86)21-51861981
Email: sales@scientiapharm.com
Country: China
ProdList: 263
Advantage: 62

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

More

Less

View Lastest Price from 3-(3-(Trifluoromethyl)phenyl)propanal manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE 21172-41-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-18

Henan Fengda Chemical Co., Ltd

Product: 3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE 21172-41-8
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-27

Henan Bao Enluo International TradeCo.，LTD

Product: 3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE 21172-41-8
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000tons
Release date: 2023-08-29

21172-41-8, 3-(3-(Trifluoromethyl)phenyl)propanalRelated Search:

(R)-(+)-1-(1-Naphthyl)ethylamine 3-(3'-TRIFLUOROMETHYL PHENYL) PROPANOL 4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID 1-NAPHTHALEN-2-YL-ETHYLAMINE 3-(Trifluoromethyl)benzaldehyde Methanesulfonic acid 3-(3-trifluoroMethylphenyl)propyl ester 1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride 3-(3-METHYLPHENYL)PROPIONIC ACID 1-NaphthaleneMethanaMine, 7,8-dihydro-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)- (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride (S)-(-)-1-(1-Naphthyl)ethylamine 1-(1-NAPHTHYL)ETHANOL 3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid 3-(Trifluoromethyl)styrene 3-(Trifluoromethyl)cinnamic acid 3-(3-METHYLPHENYL)PROPIONALDEHYDE Benzene, 1-(3-chloropropyl)-3-(trifluoroMethyl)- (E)-m-(trifluoromethyl)cinnamic acid

3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE

3-(Trifluoromethyl)benzenepropanal

m-(Trifluoromethyl)hydrocinnamaldehyde

4-[3-(trifluoroMethyl)phenyl]butanal

Benzenepropanal, 3-(trifluoroMethyl)-

3-(trifluoroMethylphenyl)propionaldehyde

3-(3-(trifluoroMethyl)phenyl)propanal

3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIOLDEHYDE

Cinacalcet Impurity 54

3-(3’-TRIFLUOROMETHYL PHENYL)PROPIONALDEHYDE

21172-41-8

Cinacalcet Intermediate

Aromatics Compounds

Aromatics