TOLYLFLUANID

Product Name: TOLYLFLUANID
CAS No.: 731-27-1
Chemical Name: TOLYLFLUANID
Synonyms: B-49854;bay5212;BAY 5212;bay49854;bay5712a;EUPAREN M;ELVARON M;BAY 49854;BAY 5712a;kue13183b
CBNumber: CB3438572
Molecular Formula: C10H13Cl2FN2O2S2
Formula Weight: 347.26
MOL File: 731-27-1.mol

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TOLYLFLUANID Property

Melting point:: 96°C
Boiling point:: 93℃
Density: 1.5132 (rough estimate)
vapor pressure: 2 x 10^-5 Pa (20 °C)
refractive index: 1.6000 (estimate)
storage temp.: -20°C
solubility: soluble in DMSO, Methanol
Colour Index: 45430
Water Solubility: 0.9 mg l^-1 (20 °C)
pka: -5.06±0.50(Predicted)
BRN: 2949607
LogP: 3.900
EPA Substance Registry System: Tolylfluanid (731-27-1)

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Safety

Hazard Codes: T,N,T+
Risk Statements: 23-36/37/38-43-48/20-50/53-50-48/23-26
Safety Statements: 24-26-37-38-45-60-61-63-36/37/39-28
RIDADR: 2588
WGK Germany: 3
RTECS: WO6560000
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 731-27-1(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H330Fatal if inhaled

H335May cause respiratory irritation

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 90619
Product name: Tolylfluanid
Purity: certified reference material, TraceCERT
Packaging: 50mg
Price: $247
Updated: 2024/03/01

Sigma-Aldrich

Product number: 32060
Product name: Tolylfluanid
Purity: PESTANAL , analytical standard
Packaging: 250mg
Price: $130
Updated: 2024/03/01

TRC

Product number: T536730
Product name: Tolylfluanide
Packaging: 250mg
Price: $130
Updated: 2021/12/16

TRC

Product number: T536730
Product name: Tolylfluanide
Packaging: 2.5g
Price: $1050
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 99614
Product name: Tolylfluanide
Packaging: 2.5g
Price: $1400
Updated: 2021/12/16

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TOLYLFLUANID Chemical Properties,Usage,Production

Uses

Tolylfluanid is used to control a wide range of fungal diseases on apples, grapes, strawberries and other fruit and storage diseases on many crops.

Uses

Tolylfluanid may be used as a reference standard for the determination of the analyte in nutraceutical formulations using dispersive liquid-liquid microextraction(DLLME) coupled with gas chromatography-mass spectrometry method.

Definition

ChEBI: A member of the class of sulfamides that is dichlofluanid in which the hydrogen at the para position of the phenyl group is replaced by a methyl group. A fungicide first marketed in 1971 and used in the cultivation of fruit and vegetables, as ell as in wood preservatives, it is no longer approved for use in the European Union.

Metabolic pathway

Tolylfluanid contains an unstable dichlorofluoromethylthio (sulfenyl) moiety that has been shown to undergo rapid hydrolytic and metabolic degradation to dimethylaminosulfotoluidide (2). By analogy with captan, presumably the dichlorofluoromethylthio moiety can be transferred to the sulfur atoms of cellular thiols such as cysteine and glutathione. Thus, in the presence of thiols tolylfluanid is probably cleaved at the N-S bond to form thiophosgene or its monofluoro analogue (3) and other gaseous products such as hydrogen sulfide, hydrogen chloride and carbonyl sulfide. Thiophosgene or its monofluoro analogue is rapidly hydrolysed by water. The dichlorofluoromethylthio group and thiophosgene may be intermediates in the formation of addition products, for example addition to cysteine affords thiazolidine-2-thione-4-carboxylica cid (4). A thiazolidine derivative of glutathione may also be formed. The main metabolic reactions in all media were cleavage of the N-S bond to give dimethylaminosulfotoluidide (2) followed by hydroxylation of the phenyl ring and oxidation of the methyl substituent on the phenyl ring. Glucoside conjugates were detected in plants and the cysteine adduct, thiazolidine-2- thione-4-carboxylic acid (4), was formed in rats.

Degradation

Tolylfluanid is hydrolysed rapidly in alkaline conditions. The hydrolytic DT₅₀ is about 12 days, 29 hours and <10 minutes at pH 4,7 and 9, respectively, at 22 °C. In the environment, hydrolysis is faster than photolysis (PM; PSD, 1995). Tolylfluanid does not absorb light of wavelength >295 nm and so photodegradation is unlikely to occur in the absence of photosensitisers.

TOLYLFLUANID Preparation Products And Raw materials

Raw materials

Preparation Products

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TOLYLFLUANID Suppliers

Canada 1 China 43 France 1 Germany 2 India 1 Japan 2 South Korea 1 Switzerland 1 United Kingdom 1 United States 5 Global 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Shenzhen Nexconn Pharmatechs Ltd.

Tel: 0755-89396905
Email: admin@nexconn.com
Country: China
ProdList: 299
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Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
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Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4511
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20806
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Raw material medicin reagent co.,Ltd

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Email: sales@njromanme.com
Country: China
ProdList: 4529
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JinJin Le Chemical Co., Ltd

Tel: 10106090
Email: jjlchem2@163.com
Country: China
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Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-0755-85201366 18938635012
Fax: 0755-85201366
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Country: China
ProdList: 9355
Advantage: 58

Twochem Co.Ltd.

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
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ProdList: 1788
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731-27-1, TOLYLFLUANIDRelated Search:

Tralkoxydim Permethrin Tau-fluvalinate Hexaconazole DICHLOFLUANID N,N-Dimethylsulfamide Dichloromonofluoromethane Dimethyl sulfide TOLYLFLUANID SOLUTION 100UG/ML IN TOLUENE 1ML TOLYLFLUANID SOLUTION 100UG/ML IN ACETONITRILE 1ML TOLYLFLUANID Sulfamide DMST

N,N-DIMETHYL-N'-TOLYL-N'-(DICHLOROFLUOROMETHYLTHIO) SULFAMIDE

TOLYFLUANID

TOLYLFLUANID

N-dichlorofluoromethylthio-N,N-dimethyl-N-p-tolylsulphamide

dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide

T0LYLFLUANID, 250MG, NEAT

TOLYLFLUANID PESTANAL, 250 MG

N-Dichlorfluormethylthio-N',N'-dimethyl-N-p-tolylsulfamid

Tolylfluanid=Tolyfluanid

tolylfluanid (bsi,iso)

EUPARENMULTI

N-(dichlorofluoromethyl)thio-N',N'-dimethyl- N-(p-tolyl)-Sulfamide n-((dichlorofluoromethyl)thio)-n',n'-dimethyl-n-(p-tolyl)-sulfamid

tolylfluanid (ISO) dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide

1,1-DICHLORO-N-[(DIMETHYLAMINO)SULFONYL]-1-FLUORO-N-(4-METHYLPHENYL)METHANESULFENAMIDE

B-49854

EUPAREN M

EUPAREN M(R)

ELVARON M

1,1-dichloro-n-((dimethylamino)sulfonyl)-1-fluoro-n-(4-methanesulfanenamid

1,1-Dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)methanesulfonamide

BAY 49854

BAY 5212

BAY 5712a

bay49854

bay5212

bay5712a

BAYER 49854

Bayer 5712a

bayer49854

N,N-Dimethyl-N'-(4-tolyl)-N'-(dichlorfluormethylthio)-sulfamid

N,N-Dimethyl-N-(4-tolyl)-N-(dichlorofluor-methylthio)-sulfamide

n,n-dimethyl-n’-(4-tolyl)-n’-(dichlorfluormethylthio)-sulfamid

n’-dichlorofluoromethylthio-n,n-dimethyl-n’-(4-tolyl)sulfamide

N'-Dichlorofluoromethylthio-N,N-dimethyl-N'-(4-tolyl)sulfamide

Sulfamide, N-((dichlorofluoromethyl)thio)-N',N'-dimethyl-N-(p-tolyl)-

Tolyfluanide

Tolylfluanide

dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide,tolylfluanid (ISO)

bayer5712a

Dichlofluanid-methyl

KUE 13183b

kue13183b

Methanesulfanenamide, 1,1-dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)-

Methanesulfenamide, 1,1-dichloro-N-[(dimethylamino)sulfonyl]-1-fluoro-N-(4-methylphenyl)-

methanesulfenamide,1,1-dichloro-n-[(dimethylamino)sulfonyl]-1-fluoro-n-(4-meth

n-((dichlorofluoromethyl)thio)-n’,n’-dimethyl-n-(p-tolyl)-sulfamid

N-([Dichloro(fluoro)methyl]sulfanyl)-N',N'-dimethyl-N-(4-methylphenyl)sulfamide

N-(dichlorofluoromethyl)thio-N’,N’-dimethyl-N-(p-tolyl)-Sulfamide

[[dichloro(fluoro)methyl]thio]-(dimethylsulfamoyl)-(4-methylphenyl)amine

N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline

N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methyl-aniline

Tolylfluanid 250mg [731-27-1]

Tolylfluanid Solution, 100ppm

Tolylfluanid Solution, 1000ppm

1,1-Dichloro-N-((Dimethylamino)Sulfonyl)-1-Fluor

Tolylfluanid Standard

Euparen M(TM)

Tolylfluanide @100 μg/mL in MeOH