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Methoxypolyethylene glycol amine

Product Name
Methoxypolyethylene glycol amine
CAS No.
80506-64-5
Chemical Name
Methoxypolyethylene glycol amine
Synonyms
mPEG-NH2;PEG NH2;mPEGn-amine;mPEG-NH2,3K;mPEG-NH2,2K;methoxyPEG amine;mPEG-NH2,MW:1000;AMINOPOLYETHYLENE;mPEG-NH2,M.W. 2000;mPEG-NH2,M.W. 4000
CBNumber
CB3442508
Molecular Formula
C5H13NO2
Formula Weight
119.16222
MOL File
80506-64-5.mol
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Methoxypolyethylene glycol amine Property

Melting point:
58-61 °C(lit.)
Flash point:
>110℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), MEtanol (Slightly)
form 
Granular Solid
color 
White to off-white
Water Solubility 
Soluble in water.
α-end
methoxy
Ω-end
amine
InChI
InChI=1S/C5H13NO2/c1-7-4-5-8-3-2-6/h2-6H2,1H3
InChIKey
QWCGXANSAOXRFE-UHFFFAOYSA-N
SMILES
C(N)COCCOC
EPA Substance Registry System
Poly(oxy-1,2-ethanediyl), .alpha.-(2-aminoethyl)-.omega.-methoxy- (80506-64-5)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
2-9
TSCA 
Yes
HS Code 
39072090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
06679
Product name
Methoxypolyethylene glycol amine
Purity
5,000, extent of labeling: ≥0.17 mmol/g NH2 loading
Packaging
1g
Price
$156
Updated
2025/07/31
Sigma-Aldrich
Product number
06676
Product name
Methoxypolyethylene glycol amine
Purity
2,000, extent of labeling: ≥0.4 mmol/g NH2 loading
Packaging
1g
Price
$315
Updated
2025/07/31
Sigma-Aldrich
Product number
767565
Product name
Poly(ethylene glycol) methyl ether amine
Purity
average Mn 500
Packaging
1ml
Price
$334.4
Updated
2025/07/31
Sigma-Aldrich
Product number
07966
Product name
Methoxypolyethylene glycol amine
Purity
20,000
Packaging
250mg
Price
$139
Updated
2025/07/31
Sigma-Aldrich
Product number
07965
Product name
Methoxypolyethylene glycol amine
Purity
10,000
Packaging
1g
Price
$266
Updated
2025/07/31
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Methoxypolyethylene glycol amine Chemical Properties,Usage,Production

Description

m-PEG15-amine is a PEG linker containing an amino group and 15 PEG units. It is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

MPEG-NH2 is a reactant in synthesis of pH-sensitive polymeric micelles for intracellular drug delivery.

Uses

Methoxypolyethylene glycol amine is generally used for the chemical modification of biologically active compounds and therapeutic agents. It has been used to increase the aqueous solubility of long-wavelength voltage-sensitive dyes and to prepare the PEG-coated fluorescent beads in studying large-scale rotational cytoplasmic flow.

Uses

PEG functionalized with amine for ligation and coupling reactions.

Application

Methoxypolyethylene glycol amine is used in the reduction of immunogenicity and increasing serum half life.Methoxypolyethylene glycol amine can:
Form dendritic micelles to enhance the solubility of hydrophobic compounds.
Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.
PEG functionalized with amine for ligation and coupling reactions.

reaction suitability

reagent type: chemical modification reagent
reactivity: carboxyl reactive

Methoxypolyethylene glycol amine Preparation Products And Raw materials

Raw materials

Preparation Products

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Methoxypolyethylene glycol amine Suppliers

NBC (Shanghai) Chemical Co.,Ltd
Tel
13671558889
Fax
021-56789108
Email
inquiry@pegderivatives.com
Country
China
ProdList
184
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
9947
Advantage
58
Xinyanpomei
Tel
15850660754
Email
15850660754@163.com
Country
China
ProdList
847
Advantage
58
Shanghai Toyang Biotechnology Co., LTD
Tel
021-59555769 13524932310
Email
1405894150@qq.com
Country
China
ProdList
995
Advantage
58
iBioMat
Tel
0571-88690234 19106834332
Email
ibmt@ibiomat.com.cn
Country
China
ProdList
45
Advantage
58
Jinan Ruiyao Mingzhi Medical Technology Co., Ltd
Tel
15662630077
Email
958367155@qq.com
Country
China
ProdList
261
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
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View Lastest Price from Methoxypolyethylene glycol amine manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER 80506-64-5
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-05
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
Methoxypoly(ethylene glycol) amine 80506-64-5
Price
US $0.00-0.00/ASSAYS
Min. Order
1化验
Purity
98%
Supply Ability
100kg
Release date
2021-06-02
Hebei Longbang Technology Co., Ltd
Product
AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER 80506-64-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-05-24

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