2,3,5,6-Tetrafluoropyridine
Synthesis Preparation Description- Product Name
- 2,3,5,6-Tetrafluoropyridine
- CAS No.
- 2875-18-5
- Chemical Name
- 2,3,5,6-Tetrafluoropyridine
- Synonyms
- 2,3,5,6-TetrafL;2,3,5,6-TETRAFLUOROPYRIDINE;Pyridine,2,3,5,6-tetrafluoro-;2,3,5,6-Tetrafluoropyridine98%;2,3,5,6-Tetrafluoropyridine,99%;2,3,5,6-Tetrafluoropyridine 98%;N-TERT-BUTYL-ALPHA-(4-NITROPHENYL)- &;2,3,5,6-Tetrafluoropyridine ISO 9001：2015 REACH
- CBNumber
- CB3444784
- Molecular Formula
- C5HF4N
- Formula Weight
- 151.06
- MOL File
- 2875-18-5.mol
2,3,5,6-Tetrafluoropyridine Property
- Boiling point:
- 102 °C (lit.)
- Density
- 1.499 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.4046(lit.)
- Flash point:
- 87 °F
- storage temp.
- Inert atmosphere,2-8°C
- pka
- -10.94±0.20(Predicted)
- form
- clear liquid
- color
- Colorless to Light yellow
- Specific Gravity
- 1.52
- InChI
- InChI=1S/C5HF4N/c6-2-1-3(7)5(9)10-4(2)8/h1H
- InChIKey
- HWIPMBCMGVXOKN-UHFFFAOYSA-N
- SMILES
- C1(F)=NC(F)=C(F)C=C1F
- CAS DataBase Reference
- 2875-18-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Pyridine, 2,3,5,6-tetrafluoro-(2875-18-5)
Safety
- Hazard Codes
- Xi,F,C
- Risk Statements
- 10-36/37/38
- Safety Statements
- 28-36
- RIDADR
- UN 1993 3/PG 3
- WGK Germany
- 3
- Hazard Note
- Flammable/Irritant
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 316679
- Product name
- 2,3,5,6-Tetrafluoropyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $65.2
- Updated
- 2023/06/20
- Product number
- T1778
- Product name
- 2,3,5,6-Tetrafluoropyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $48
- Updated
- 2024/03/01
- Product number
- T1778
- Product name
- 2,3,5,6-Tetrafluoropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $144
- Updated
- 2024/03/01
- Product number
- B21905
- Product name
- 2,3,5,6-Tetrafluoropyridine, 97%
- Packaging
- 1g
- Price
- $41.1
- Updated
- 2021/12/16
- Product number
- B21905
- Product name
- 2,3,5,6-Tetrafluoropyridine, 97%
- Packaging
- 5g
- Price
- $140
- Updated
- 2021/12/16
2,3,5,6-Tetrafluoropyridine Chemical Properties,Usage,Production
Synthesis
Catalytic reduction of aryl chlorides, bromides and iodides is well documented,
however, aryl fluorides do not readily react under these conditions, owing to the strong
C-F bond and the high activation barrier to bond breaking. Work in our laboratories showed that at high temperatures, pentafluoropyridine was converted to 2,3,5,6-
tetrafluoropyridine using a palladium catalyst.
Preparation
An autoclave sprayed with PTFE was charged with pentafluoropyridine (20.0 g, 118 mmol), HBr (32.0 g, 400 mmol) and sulpholane (40 cm3) and heated at 200 ℃ for 48 h. The mixture was added to water and extracted into ether. The ether solution was shown to contain pentafluoropyridine (79%) and 2,3,5,6-tetrafluoropyridine (21%) by comparison of their GCMS and fluorine nmr spectra with authentic samples.
Description
Pyridine and its derivatives have been developed and utilized relatively early at home and abroad. It is widely used in medicine, pesticides, rubber, dyes and other fields. Since the 1960s, there have been hundreds of medicines, pesticides, dyes, and some special reagents developed with fluorine-containing aromatic compounds as intermediates. In the weakly basic pyridine ring, the nitrogen atom is more negatively charged, and then a fluorine atom with a strong electronegativity is introduced to synthesize a fluorine-containing pyridine intermediate.
Chemical Properties
clear colorless liquid
2,3,5,6-Tetrafluoropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,3,5,6-Tetrafluoropyridine manufacturers
- Product
- 2,3,5,6-Tetrafluoropyridine 2875-18-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
- Product
- 2,3,5,6-Tetrafluoropyridine 2875-18-5
- Price
- US $5.00-0.20/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-02
- Product
- 2,3,5,6-Tetrafluoropyridine 2875-18-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%Min
- Supply Ability
- 1000kg
- Release date
- 2023-03-14