Deoxycorticosterone acetate
- Product Name
- Deoxycorticosterone acetate
- CAS No.
- 56-47-3
- Chemical Name
- Deoxycorticosterone acetate
- Synonyms
- doxo;DOCA;arcort;steraq;cortate;ocriten;syncort;Decorten;cortacet;cortenil
- CBNumber
- CB3462948
- Molecular Formula
- C23H32O4
- Formula Weight
- 372.5
- MOL File
- 56-47-3.mol
Deoxycorticosterone acetate Property
- Melting point:
- 157°C
- alpha
- D20 +168 to +176° (dioxane)
- Boiling point:
- 421.94°C (rough estimate)
- Density
- 1.0415 (rough estimate)
- refractive index
- 175 ° (C=1, Dioxane)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- H2O: insoluble
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 4mg/L(25 ºC)
- Merck
- 2901
- BRN
- 2570798
- InChI
- InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1
- InChIKey
- VPGRYOFKCNULNK-ACXQXYJUSA-N
- SMILES
- C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2
- LogP
- 3.080
- CAS DataBase Reference
- 56-47-3(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- RIDADR
- UN 2811
- WGK Germany
- 3
- RTECS
- HG0525000
- HazardClass
- IRRITANT
- HS Code
- 2937290000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H360May damage fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P314Get medical advice/attention if you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D7000
- Product name
- Deoxycorticosterone acetate
- Packaging
- 1g
- Price
- $207
- Updated
- 2024/03/01
- Product number
- 1174001
- Product name
- Deoxycorticosterone acetate
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $174.4
- Updated
- 2024/03/01
- Product number
- D7000
- Product name
- Deoxycorticosterone acetate
- Packaging
- 5g
- Price
- $673
- Updated
- 2024/03/01
- Product number
- D7000
- Product name
- Deoxycorticosterone acetate
- Packaging
- 25g
- Price
- $1590
- Updated
- 2024/03/01
- Product number
- D0400000
- Product name
- Desoxycortone acetate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- d0400000
- Price
- $220
- Updated
- 2024/03/01
Deoxycorticosterone acetate Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
Adrenocortical/mineralocorticoid Steroid.
Uses
Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Definition
ChEBI: Deoxycorticosterone acetate is a corticosteroid hormone.
brand name
Doca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.].
General Description
Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.
Purification Methods
11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]
Deoxycorticosterone acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Deoxycorticosterone acetate Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
View Lastest Price from Deoxycorticosterone acetate manufacturers
- Product
- Deoxycorticosterone acetate 56-47-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99.1
- Supply Ability
- 100KG
- Release date
- 2024-05-09
- Product
- corticosterone 56-47-3
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2023-11-02
- Product
- Deoxycorticosterone acetate 56-47-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2023-08-28