ChemicalBook > CAS DataBase List > Deoxycorticosterone acetate

Deoxycorticosterone acetate

Product Name
Deoxycorticosterone acetate
CAS No.
56-47-3
Chemical Name
Deoxycorticosterone acetate
Synonyms
doxo;DOCA;arcort;steraq;cortate;ocriten;syncort;Decorten;cortacet;cortenil
CBNumber
CB3462948
Molecular Formula
C23H32O4
Formula Weight
372.5
MOL File
56-47-3.mol
More
Less

Deoxycorticosterone acetate Property

Melting point:
157°C
alpha 
D20 +168 to +176° (dioxane)
Boiling point:
421.94°C (rough estimate)
Density 
1.0415 (rough estimate)
refractive index 
175 ° (C=1, Dioxane)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: insoluble
color 
White to Off-White
Water Solubility 
4mg/L(25 ºC)
Merck 
2901
BRN 
2570798
InChI
InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1
InChIKey
VPGRYOFKCNULNK-ACXQXYJUSA-N
SMILES
C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2
LogP
3.080
CAS DataBase Reference
56-47-3(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
22-24/25
RIDADR 
UN 2811
WGK Germany 
3
RTECS 
HG0525000
HazardClass 
IRRITANT
HS Code 
2937290000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
1g
Price
$207
Updated
2024/03/01
Sigma-Aldrich
Product number
1174001
Product name
Deoxycorticosterone acetate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$174.4
Updated
2024/03/01
Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
5g
Price
$673
Updated
2024/03/01
Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
25g
Price
$1590
Updated
2024/03/01
Sigma-Aldrich
Product number
D0400000
Product name
Desoxycortone acetate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
d0400000
Price
$220
Updated
2024/03/01
More
Less

Deoxycorticosterone acetate Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Adrenocortical/mineralocorticoid Steroid.

Uses

Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.

Definition

ChEBI: Deoxycorticosterone acetate is a corticosteroid hormone.

brand name

Doca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.].

General Description

Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.

Purification Methods

11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]

Deoxycorticosterone acetate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Deoxycorticosterone acetate Suppliers

Wuhan Dingtong Pharmaceutical Co., Ltd
Tel
027-027-59207795 18327179646
Fax
027-59207795
Email
18327179646@163.com
Country
China
ProdList
1943
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
Tel
18858184290; 18858184290
Fax
0086-571-28313105
Email
sales@zyterpharm.com
Country
China
ProdList
48
Advantage
49
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8850
Advantage
52
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1937
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
24835
Advantage
65
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 15920483169
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17944
Advantage
56
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2079
Advantage
56
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15873
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Beijing NuoqiYa Biotechnology Co., Ltd.
Tel
4000-819-385 010-62329685 13718666987
Fax
010-62340519
Country
China
ProdList
1971
Advantage
55
Jinan Putubio Tech Co., Ltd.
Tel
+86 (531) 8099-2215
Fax
+86 (531) 8099-2215
Email
putubio@outlook.com
Country
China
ProdList
1261
Advantage
55
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3868
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
Raw material medicin reagent co.,Ltd
Tel
025-57798860
Email
sales@njromanme.com
Country
China
ProdList
4534
Advantage
58
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973185 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Hubei widely chemical technology Co., Ltd.
Tel
027-83991130 18627774460
Fax
027-83991130
Email
1718093273@qq.com
Country
China
ProdList
1890
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
132020
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-59402396 13419635609
Fax
027-83989310
Email
13419635609@163.com
Country
China
ProdList
1910
Advantage
55
Wellman Pharmaceutical Group Limited
Tel
027-027-83778875 15807197853
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3974
Advantage
58
Wuhan Netcom Electronic Commerce Limited
Tel
18064670521
Fax
0757-88210752
Email
2355935187@ycphar.com
Country
China
ProdList
4887
Advantage
58
Zhuhai JiaYi Biological Technology Co., Ltd.
Tel
18578209868 2355327026
Fax
18578209868 QQ:2355327026
Email
steroidbest@hotmail.com
Country
China
ProdList
6504
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-83778895 18602735115
Fax
027-51119224
Email
18602735115@163.com
Country
China
ProdList
1991
Advantage
64
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10003
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
400-400-400-9004166 18117592386
Email
3007522982@qq.com
Country
China
ProdList
52712
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-62971590 18548936886
Fax
010-62340519
Email
3462612863@qq.com
Country
China
ProdList
6912
Advantage
58
Hefei Bomei Biotechnology Co., Ltd.
Tel
13739298932
Email
531626407@qq.com
Country
China
ProdList
3000
Advantage
58
Guangzhou Tomums Life Science Co., Ltd.
Tel
020-31155029 18902330969
Fax
020-31155029
Email
sales@tomums.cn
Country
China
ProdList
4698
Advantage
58
TCI Chemicals
Tel
021-67121386, 800-988-0390
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
5391
Advantage
58
TOSUN PHARM
Tel
13326451905
Email
2881290884@qq.com
Country
China
ProdList
7386
Advantage
58
Henan Alfa Chemical Co., Ltd
Tel
+8618339805032
Email
alfa4@alfachem.cn
Country
China
ProdList
12759
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
0551-65418671
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34572
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652,+86-571- 88492614
Email
info@dycnchem.com
Country
CHINA
ProdList
52867
Advantage
58
Baoji Guokang Bio-Technology Co., Ltd.
Tel
0917-3909592 13892490616
Fax
09173909592
Email
gksales1@gk-bio.com
Country
China
ProdList
9340
Advantage
58
More
Less

View Lastest Price from Deoxycorticosterone acetate manufacturers

Nantong Guangyuan Chemicl Co,Ltd
Product
corticosterone 56-47-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-11-02
Wuhan Han Sheng New Material Technology Co.,Ltd
Product
Deoxycorticosterone acetate 56-47-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50tons
Release date
2023-08-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
Deoxycorticosterone acetate 56-47-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

56-47-3, Deoxycorticosterone acetate Related Search:


  • 21-HYDROXYPROGESTERONE 21-ACETATE VETRAN
  • 11-Deoxycorticosterone acetate, 21-Acetoxy-4-pregnene-3,20-dione, 21-Acetoxyprogesterone, 21-Hydroxy-4-pregnene-3,20-dione 21-acetate, 21-Hydroxyprogesterone 21-acetate, 4-Pregnen-21-ol-3,20-dione 21-acetate, Cortexone acetate, DOC acetate
  • 21-Acetoxypregn-4-en-3,20-dione
  • 21-Hydroxypregn-4-ene-3,20-dione Acetate
  • Decorten
  • Decosteron
  • DEOXYCORTICOSTERONE ACETATE(RG)
  • Desoxycorticosterone Acetate (200 mg)
  • 3,20-Dioxopregn-4-en-21-yl acetate
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
  • DOCA(Deoxycorticosterone acetate)
  • arcort
  • bio-corten
  • cortacet
  • cortate
  • cortenil
  • cortesan
  • cortifar
  • cortigen
  • cortinaq
  • cortiron
  • cortivis
  • cortixyl
  • decosterone
  • decostrate
  • deoxy-corticosteronacetate
  • deoxycortoneacetate
  • descorterone
  • descotone
  • desoxycorticosterone-21-acetate
  • dorcostrin
  • doxo
  • doxycamon
  • krinocorts
  • ocriten
  • organon’sdocaacetate
  • percorten
  • percotol
  • Pregn-4-en-21-ol-3,20-dione21-acetate
  • primocort
  • primocortan
  • sincortex
  • steraq
  • syncort
  • syncorta
  • syncortyl
  • 11-DEOXYCORTICOSTERONE ACETATE; DOC ACETATE; CORTEXONE ACETATE
  • 4-pregnene-3,20-dione-21-olacetate
  • unidocan
  • 11-deoxycorticosterone21-acetate
  • 20-dione,21-hydroxy-pregn-4-ene-acetate
  • 21-acetoxy-3,20-diketopregn-4-ene
  • 21-Acetyloxypregn-4-ene-3,20-dione
  • 21-hydroxypregn-4-ene-3,20-dione21-acetate
  • 11-DEOXYCORTICOSTERONE ACETATE
  • 11-desoxycorticosterone acetate
  • 21-ACETOXYPROGESTERONE
  • 21-ACETOXY-4-PREGNENE-3,20-DIONE