ChemicalBook > CAS DataBase List > Deoxycorticosterone acetate

Deoxycorticosterone acetate

Product Name
Deoxycorticosterone acetate
CAS No.
56-47-3
Chemical Name
Deoxycorticosterone acetate
Synonyms
doxo;DOCA;arcort;steraq;cortate;ocriten;syncort;Decorten;cortacet;cortenil
CBNumber
CB3462948
Molecular Formula
C23H32O4
Formula Weight
372.5
MOL File
56-47-3.mol
More
Less

Deoxycorticosterone acetate Property

Melting point:
157°C
alpha 
D20 +168 to +176° (dioxane)
Boiling point:
421.94°C (rough estimate)
Density 
1.0415 (rough estimate)
refractive index 
175 ° (C=1, Dioxane)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: insoluble
form 
Solid
color 
White to Off-White
biological source
synthetic (organic)
Water Solubility 
4mg/L(25 ºC)
Merck 
2901
BRN 
2570798
InChI
InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1
InChIKey
VPGRYOFKCNULNK-ACXQXYJUSA-N
SMILES
C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2
LogP
3.080
CAS DataBase Reference
56-47-3(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
22-24/25
RIDADR 
UN 2811
WGK Germany 
3
RTECS 
HG0525000
HazardClass 
IRRITANT
HS Code 
2937290000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
1g
Price
$207
Updated
2024/03/01
Sigma-Aldrich
Product number
1174001
Product name
Deoxycorticosterone acetate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$174.4
Updated
2024/03/01
Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
5g
Price
$673
Updated
2024/03/01
Sigma-Aldrich
Product number
D7000
Product name
Deoxycorticosterone acetate
Packaging
25g
Price
$1590
Updated
2024/03/01
Sigma-Aldrich
Product number
D0400000
Product name
Desoxycortone acetate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
d0400000
Price
$220
Updated
2024/03/01
More
Less

Deoxycorticosterone acetate Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Adrenocortical/mineralocorticoid Steroid.

Uses

Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.

Definition

ChEBI: Deoxycorticosterone acetate is a corticosteroid hormone.

brand name

Doca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.].

General Description

Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.

Purification Methods

11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]

Deoxycorticosterone acetate Preparation Products And Raw materials

Raw materials

Dry acetone Calcium oxide Progesterone Tetrahydrofuran Potassium Acetate

Preparation Products

5A-PREGNAN-21-OL-3-20-DIONE CRYSTALLINE
More
Less

Deoxycorticosterone acetate Suppliers

Canada 1 China 198 Europe 3 France 3 Germany 4 India 8 Japan 3 Russia 1 Switzerland 1 United Kingdom 12 United States 36 Global 270
Wuhan Dingtong Pharmaceutical Co., Ltd
Tel
027-59207795 18327179646
Fax
027-59207795
Email
18327179646@163.com
Country
China
ProdList
1951
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
Tel
18858184290; 18858184290
Fax
0086-571-28313105
Email
sales@zyterpharm.com
Country
China
ProdList
48
Advantage
49
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9810
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8161
Advantage
52
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1931
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 1316706386
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18110
Advantage
56
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2045
Advantage
56
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Beijing NuoqiYa Biotechnology Co., Ltd.
Tel
4000-819-385 010-62329685 13718666987
Fax
010-62340519
Country
China
ProdList
1971
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Jinan Putubio Tech Co., Ltd.
Tel
+86 (531) 8099-2215
Fax
+86 (531) 8099-2215
Email
putubio@outlook.com
Country
China
ProdList
1261
Advantage
55
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29763
Advantage
68
Hubei widely chemical technology Co., Ltd.
Tel
027-83991130 18627774460
Fax
027-83991130
Email
1718093273@QQ.COM
Country
China
ProdList
1669
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-59402396 13419635609
Fax
027-83989310
Email
13419635609@163.com
Country
China
ProdList
1919
Advantage
55
Wuhai Shuou Technology Co., Ltd.
Tel
17792809151
Fax
18872220797
Email
2355916837@ycphar.com
Country
China
ProdList
6133
Advantage
55
Wellman Pharmaceutical Group Limited
Tel
027-83778875 15807197853
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3919
Advantage
58
Wuhan Netcom Electronic Commerce Limited
Tel
18064670521
Fax
0757-88210752
Email
2355935187@ycphar.com
Country
China
ProdList
4879
Advantage
58
Zhuhai JiaYi Biological Technology Co., Ltd.
Tel
18578209868 2355327026
Fax
18578209868 QQ：2355327026
Email
steroidbest@hotmail.com
Country
China
ProdList
6501
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-83778895 18602735115
Fax
027-51119224
Email
18602735115@163.com
Country
China
ProdList
1956
Advantage
64
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10347
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-010-010-62971590 18548936886
Fax
010-62340519
Email
jack@oka-vip.com
Country
China
ProdList
6897
Advantage
58
Hefei Bomei Biotechnology Co., Ltd.
Tel
13739298932
Email
531626407@qq.com
Country
China
ProdList
3010
Advantage
58
Guangzhou Tomums Life Science Co., Ltd.
Tel
020-31155029 18902330969
Fax
020-31155029
Email
sales@tomums.cn
Country
China
ProdList
4696
Advantage
58
TCI Chemicals
Tel
021-67121386, 800-988-0390
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
5391
Advantage
58
TOSUN PHARM
Tel
020-61855200 13326451905
Email
260366801@qq.com
Country
China
ProdList
7851
Advantage
58
Wuhan Fortuna Chemical Co., Ltd
Tel
+86-027-59207850
Fax
86-27-59524646
Email
info@fortunachem.com
Country
China
ProdList
5965
Advantage
58
More
Less

View Lastest Price from Deoxycorticosterone acetate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Deoxycorticosterone acetate 56-47-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.1
Supply Ability
100KG
Release date
2024-05-09
Nantong Guangyuan Chemicl Co,Ltd
Product
corticosterone 56-47-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-11-02
Wuhan Han Sheng New Material Technology Co.，Ltd
Product
Deoxycorticosterone acetate 56-47-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50tons
Release date
2023-08-28

56-47-3, Deoxycorticosterone acetate Related Search:

Ethyl acetate Cellulose acetate Desoxycorticosterone CHLOROPHOSPHONAZO III Chenodeoxycholic acid CORTICOSTERONE POLY(VINYL ACETATE) Vinyl acetate Glatiramer acetate Ammonium acetate Epiandrosterone acetate Ursodeoxycholic acid Sodium acetate 16-Dehydropregnenolone acetate ACETATE (-)-2-[METHYLAMINO]-1-PHENYLPROPANE Hydrocortisone sodium succinate REICHSTEIN'S SUBSTANCE S 21-ACETATE

  • 21-HYDROXYPROGESTERONE 21-ACETATE VETRAN
  • 11-Deoxycorticosterone acetate, 21-Acetoxy-4-pregnene-3,20-dione, 21-Acetoxyprogesterone, 21-Hydroxy-4-pregnene-3,20-dione 21-acetate, 21-Hydroxyprogesterone 21-acetate, 4-Pregnen-21-ol-3,20-dione 21-acetate, Cortexone acetate, DOC acetate
  • 21-Acetoxypregn-4-en-3,20-dione
  • 21-Hydroxypregn-4-ene-3,20-dione Acetate
  • Decorten
  • Decosteron
  • DEOXYCORTICOSTERONE ACETATE(RG)
  • Desoxycorticosterone Acetate (200 mg)
  • 3,20-Dioxopregn-4-en-21-yl acetate
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
  • DOCA(Deoxycorticosterone acetate)
  • arcort
  • bio-corten
  • cortacet
  • cortate
  • cortenil
  • cortesan
  • cortifar
  • cortigen
  • cortinaq
  • cortiron
  • cortivis
  • cortixyl
  • decosterone
  • decostrate
  • deoxy-corticosteronacetate
  • deoxycortoneacetate
  • descorterone
  • descotone
  • desoxycorticosterone-21-acetate
  • dorcostrin
  • doxo
  • doxycamon
  • krinocorts
  • ocriten
  • organon’sdocaacetate
  • percorten
  • percotol
  • Pregn-4-en-21-ol-3,20-dione21-acetate
  • primocort
  • primocortan
  • sincortex
  • steraq
  • syncort
  • syncorta
  • syncortyl
  • 11-DEOXYCORTICOSTERONE ACETATE; DOC ACETATE; CORTEXONE ACETATE
  • 4-pregnene-3,20-dione-21-olacetate
  • unidocan
  • 11-deoxycorticosterone21-acetate
  • 20-dione,21-hydroxy-pregn-4-ene-acetate
  • 21-acetoxy-3,20-diketopregn-4-ene
  • 21-Acetyloxypregn-4-ene-3,20-dione
  • 21-hydroxypregn-4-ene-3,20-dione21-acetate
  • 11-DEOXYCORTICOSTERONE ACETATE
  • 11-desoxycorticosterone acetate
  • 21-ACETOXYPROGESTERONE
  • 21-ACETOXY-4-PREGNENE-3,20-DIONE