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CALCISEPTINE

Product Name
CALCISEPTINE
CAS No.
178805-91-9
Chemical Name
CALCISEPTINE
Synonyms
CAS;CSE1;XPO2;Exportin-2;CALCISEPTINE;Calciseptine (Recombinant);CSE1 chromosome segregation 1-like;chromosome segregation 1-like protein;CALCISEPTINE, DENDROASPIS POLYLEPIS POLYLEPIS;Anti-CSE1L, N-Terminal antibody produced in rabbit
CBNumber
CB3472613
Formula Weight
0
MOL File
Mol file
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CALCISEPTINE Property

storage temp. 
-20°C
Sequence
Arg-Ile-Cys-Tyr-Ile-His-Lys-Ala-Ser-Leu-Pro-Arg-Ala-Thr-Lys-Thr-Cys-Val-Glu-Asn-Thr-Cys-Tyr-Lys-Met-Phe-Ile-Arg-Thr-Gln-Arg-Glu-Tyr-Ile-Ser-Glu-Arg-Gly-Cys-Gly-Cys-Pro-Thr-Ala-Met-Trp-Pro-Tyr-Gln-Thr-Glu-Cys-Cys-Lys-Gly-Asp-Arg-Cys-Asn-Lys (Disulfide bridge:Cys3-Cys22;Cys17-Cys39;Cys41-Cys52; Cys53-Cys58)
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Hazard and Precautionary Statements (GHS)

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CALCISEPTINE Chemical Properties,Usage,Production

Uses

Calciseptine, a natural?neurotoxin?isolated from the black mamba Dendroaspis p. polylepis venom. Calciseptine consists of 60 amino acids with four disulfide bonds. Calciseptine specifically blocks L-type?calcium channel[1].

IC 50

L-type calcium channel: 15 nM (IC50)

References

[1] H Schweitz, et al. Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons. Proc Natl Acad Sci U S A. 1994 Feb 1; 91(3): 878–882. DOI:10.1073/pnas.91.3.878

CALCISEPTINE Preparation Products And Raw materials

Raw materials

Preparation Products

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CALCISEPTINE Suppliers

China 11 Germany 1 United States 4 Global 16
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Accurate Chemical & Scientific Corporation.
Tel
--
Fax
--
Country
United States
ProdList
6747
Advantage
72
Peptides International, Inc.
Tel
--
Fax
--
Email
peptides@pepnet.com
Country
United States
ProdList
555
Advantage
72

178805-91-9, CALCISEPTINERelated Search:

Toxins and Analogues ODK2 KURTOXIN ODK2 analogues μ-conotoxin GlllA SHK TOXIN OMEGA-AGATOXIN IVA SSD609 HUWENTOXIN IV mu-conotoxin PLTX-ll ω-conotoxin MVllA Dendrotoxin-l ω-agatoxin IVB SNX-482 Mambalgin-3 a-conotoxin lml CALCISEPTINE,CALCISEPTINE, DENDROASPIS POLYLEPIS POLYLEPIS

  • ARG-ILE-CYS-TYR-ILE-HIS-LYS-ALA-SER-LEU-PRO-ARG-ALA-THR-LYS-THR-CYS-VAL-GLU -ASN-THR-CYS-TYR-LYS-MET-PHE-ILE-ARG-THR-GLN-ARG-GLU-TYR-ILE-SER-GLU-ARG-GLY-CYS-GLY-CYS-PRO-THR-ALA-MET-TRP-PRO-TYR-GLN-THR-GLU-CYS-CYS-LYS-GLY-ASP-CYS -ASN-LYS
  • CAS
  • CALCISEPTINE, DENDROASPIS POLYLEPIS POLYLEPIS
  • CALCISEPTINE
  • Calciseptine from Dendroaspis polylepis polylepis (black mamba)
  • ANTI-CELLULAR APOPTOSIS SUSCEPTIBILITY(C-TERMINAL) antibody produced in rabbit
  • Exportin-2
  • XPO2
  • Anti-CSE1L, N-Terminal antibody produced in rabbit
  • chromosome segregation 1-like protein
  • CSE1
  • CSE1 chromosome segregation 1-like
  • Calciseptine (Recombinant)
  • 178805-91-9