SCOPARONE
- Product Name
- SCOPARONE
- CAS No.
- 120-08-1
- Chemical Name
- SCOPARONE
- Synonyms
- scoparon;SCOPARONE;escoparone;AKOS 236-43;Scoparone-RM;SCOPARONE(RG);DIMETHYLESCULETIN;DIMETHOXYCOUMARIN;Scoparone 120-08-1;SCOPARONE(RG) 10mg
- CBNumber
- CB3486326
- Molecular Formula
- C11H10O4
- Formula Weight
- 206.19
- MOL File
- 120-08-1.mol
SCOPARONE Property
- Melting point:
- 143-145 °C (lit.)
- Boiling point:
- 265.04°C (rough estimate)
- Density
- 1.0858 (rough estimate)
- refractive index
- 1.4389 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- >8.4mg/mL in DMSO
- form
- Powder
- color
- Light yellow to yellow
- Merck
- 13,8479
- LogP
- 1.331 (est)
- CAS DataBase Reference
- 120-08-1(CAS DataBase Reference)
- NIST Chemistry Reference
- 2H-1-benzopyran-2-one, 6,7-dimethoxy-(120-08-1)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 23/24/25-36-22
- Safety Statements
- 27/28-36/37/39-45-26
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- GN6550000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29322090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 254886
- Product name
- 6,7-Dimethoxycoumarin
- Purity
- 98%
- Packaging
- 250mg
- Price
- $170
- Updated
- 2024/03/01
- Product number
- 254886
- Product name
- 6,7-Dimethoxycoumarin
- Purity
- 98%
- Packaging
- 1g
- Price
- $377
- Updated
- 2024/03/01
- Product number
- 20046
- Product name
- Scoparone
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 20046
- Product name
- Scoparone
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 20046
- Product name
- Scoparone
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $214
- Updated
- 2024/03/01
SCOPARONE Chemical Properties,Usage,Production
Uses
Scoparone-13C2D6 is a by-product in the synthesis of Scopoletin-13C,d3 (S200502). Scopoletin-13C,d3, is the labeled analogue of Scopoletin (S200500), used for cosmetics, topical formulations, and foods. Scoparone-13C2D6 is also the labeled form of Scoparone (S199980), which regulates the expression of Th1/Th2 cytokines and IgE and is effective in treating allergic rhinitis.
Definition
ChEBI: Scoparone is a member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. It has a role as a plant metabolite, an anti-inflammatory agent, an antilipemic drug, an immunosuppressive agent, an antihypertensive agent and an anti-allergic agent. It is a member of coumarins and an aromatic ether. It is functionally related to an esculetin.
Synthesis Reference(s)
Synthesis, p. 1026, 1986 DOI: 10.1055/s-1986-31859
General Description
6,7-Dimethoxycoumarin inhibits the in vitro growth of Phytophthora citrophthora, Verticillium dahliae, Penicillium digitatum, P. italicum, Colletotrichum gloeosporioides, Diplodia natalensis and Hendersonula toruloidea. Determination and pharmacokinetic study of 6,7-dimethoxycoumarin in rat plasma after intragastric administration of different decoctions of Yinchenhao Tang by reversed-phase HPLC method with UV detection has been reported.
Safety Profile
Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. An anthypertensive agent. When heated to decomposition it emits acrid smoke and irritating fumes.
SCOPARONE Preparation Products And Raw materials
Raw materials
Preparation Products
SCOPARONE Suppliers
- Tel
- --
- Fax
- --
- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
- Advantage
- 74
View Lastest Price from SCOPARONE manufacturers
- Product
- 6,7-Dimethoxycoumarin 120-08-1
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-09-27
- Product
- 6,7-Dimethoxycoumarin 120-08-1
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- Analytical Standard
- Supply Ability
- 10 g
- Release date
- 2019-09-27
- Product
- Scoparone 120-08-1 120-08-1
- Price
- US $10.50/mg
- Min. Order
- 20mg
- Purity
- ≥98%
- Supply Ability
- 1000.00 KGS
- Release date
- 2019-07-10