SCOPARONE

Product Name: SCOPARONE
CAS No.: 120-08-1
Chemical Name: SCOPARONE
Synonyms: scoparon;SCOPARONE;escoparone;AKOS 236-43;Scoparone-RM;SCOPARONE(RG);DIMETHYLESCULETIN;DIMETHOXYCOUMARIN;Scoparone 120-08-1;SCOPARONE(RG) 10mg
CBNumber: CB3486326
Molecular Formula: C11H10O4
Formula Weight: 206.19
MOL File: 120-08-1.mol

More

Less

SCOPARONE Property

Melting point:: 143-145 °C (lit.)
Boiling point:: 265.04°C (rough estimate)
Density: 1.0858 (rough estimate)
refractive index: 1.4389 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: >8.4mg/mL in DMSO
form: Powder
color: Light yellow to yellow
Merck: 13,8479
LogP: 1.331 (est)
CAS DataBase Reference: 120-08-1(CAS DataBase Reference)
NIST Chemistry Reference: 2H-1-benzopyran-2-one, 6,7-dimethoxy-(120-08-1)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 23/24/25-36-22
Safety Statements: 27/28-36/37/39-45-26
RIDADR: 2811
WGK Germany: 3
RTECS: GN6550000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29322090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 254886
Product name: 6,7-Dimethoxycoumarin
Purity: 98%
Packaging: 250mg
Price: $170
Updated: 2024/03/01

Sigma-Aldrich

Product number: 254886
Product name: 6,7-Dimethoxycoumarin
Purity: 98%
Packaging: 1g
Price: $377
Updated: 2024/03/01

Cayman Chemical

Product number: 20046
Product name: Scoparone
Purity: ≥98%
Packaging: 10mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 20046
Product name: Scoparone
Purity: ≥98%
Packaging: 25mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 20046
Product name: Scoparone
Purity: ≥98%
Packaging: 50mg
Price: $214
Updated: 2024/03/01

More

Less

SCOPARONE Chemical Properties,Usage,Production

Uses

Scoparone-13C2D6 is a by-product in the synthesis of Scopoletin-13C,d3 (S200502). Scopoletin-13C,d3, is the labeled analogue of Scopoletin (S200500), used for cosmetics, topical formulations, and foods. Scoparone-13C2D6 is also the labeled form of Scoparone (S199980), which regulates the expression of Th1/Th2 cytokines and IgE and is effective in treating allergic rhinitis.

Definition

ChEBI: Scoparone is a member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. It has a role as a plant metabolite, an anti-inflammatory agent, an antilipemic drug, an immunosuppressive agent, an antihypertensive agent and an anti-allergic agent. It is a member of coumarins and an aromatic ether. It is functionally related to an esculetin.

Synthesis Reference(s)

Synthesis, p. 1026, 1986 DOI: 10.1055/s-1986-31859

General Description

6,7-Dimethoxycoumarin inhibits the in vitro growth of Phytophthora citrophthora, Verticillium dahliae, Penicillium digitatum, P. italicum, Colletotrichum gloeosporioides, Diplodia natalensis and Hendersonula toruloidea. Determination and pharmacokinetic study of 6,7-dimethoxycoumarin in rat plasma after intragastric administration of different decoctions of Yinchenhao Tang by reversed-phase HPLC method with UV detection has been reported.

Safety Profile

Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. An anthypertensive agent. When heated to decomposition it emits acrid smoke and irritating fumes.

SCOPARONE Preparation Products And Raw materials

Raw materials

Esculetin Dimethyl sulfate

Preparation Products

More

Less

SCOPARONE Suppliers

China 230 France 1 Germany 6 India 5 Japan 1 South Korea 1 Switzerland 1 United Kingdom 10 United States 26 USA 1 Global 282

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Santa Cruz Biotechnology, Inc.

Tel: --
Fax: --
Email: scbt@scbt.com
Country: United States
ProdList: 3597
Advantage: 60

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

INDOFINE Chemical Company, Inc.

Tel: --
Fax: --
Email: chemical@indofinechemical.com
Country: United States
ProdList: 6176
Advantage: 69

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

Fine Chem Trading LTD

Tel: --
Fax: --
Email: chemfinder@chemfinder.co.uk
Country: United States
ProdList: 1609
Advantage: 64

EMD Biosciences, Inc.

Tel: --
Fax: --
Email: technical@calbiochem.com
Country: United States
ProdList: 6529
Advantage: 66

MP Biomedicals, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6561
Advantage: 81

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Sinova Inc.

Tel: --
Fax: --
Email: sales@sinovainc.com
Country: United States
ProdList: 4009
Advantage: 58

ChromaDex

Tel: --
Fax: --
Email: sales@chromadex.com
Country: United States
ProdList: 2501
Advantage: 76

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

More

Less

View Lastest Price from SCOPARONE manufacturers

Shanghai Standard Technology Co., Ltd.

Product: 6,7-Dimethoxycoumarin 120-08-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-09-27

Shanghai Standard Technology Co., Ltd.

Product: 6,7-Dimethoxycoumarin 120-08-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: Analytical Standard
Supply Ability: 10 g
Release date: 2019-09-27

NanJing Spring & Autumn Biological Engineering CO., LTD.

Product: Scoparone 120-08-1 120-08-1
Price: US $10.50/mg
Min. Order: 20mg
Purity: ≥98%
Supply Ability: 1000.00 KGS
Release date: 2019-07-10

120-08-1, SCOPARONERelated Search:

6,7-Diethoxy-4-(trifluoromethyl)coumarin 6,7-DIMETHOXY-4-METHYLCOUMARIN 6,7,8-TRIMETHOXYCOUMARIN ESCULETIN DIBENZYL ETHER Oxamarin 8-ACETYL DIMETHOXYCOUMARIN SCOPARONE 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN FRAXIDIN 5,7-Dimethoxycoumarin Dimethyl ether Coumarin Esculetin 6,7-DIMETHOXY-4-ETHYLCOUMARIN 6,7-DIACETOXY-4-METHYLCOUMARIN scopolin 6,7-DIMETHOXY-4-(TRIFLUOROMETHYL)COUMARIN 6,7-DIMETHOXYCOUMARIN-4-ACETIC ACID

Scoparone 120-08-1

6,7-dihydroxy-3,4-dimethyl-1-benzopyran-2-one

6,7-dimethoxy-coumari

6,7-Dimethoxycoumarine

aesculetindimethylether

escoparone

scoparon

6,7-DIMETHOXY-CHROMEN-2-ONE

6,7-DIMETHOXYCOUMARIN

6,7-DIMETHYLESCULETIN

AKOS 236-43

ESCULETIN DIMETHYL ETHER

DIMETHYLESCULETIN

SCOPARONE

6,7-Dimethoxycoumarin, 98%, from Ligusticum chuanxiong Hort.

6,7-Dimethoxy-2H-1-benzopyran-2-one

6,7-dimethoxy-benzopyran-2-on

6,7-dimethoxybenzopyran-2-one

6,7-dimethoxy-2-benzopyrone

SCOPARONE, 98% BY HPLC

SCOPARONE(RG)

DIMETHOXYCOUMARIN

6,7-DIMETHYLESCULETIN WITH HPLC

2H-1-Benzopyran-2-one, 6,7-dimethoxy-

Scoparone，6,7-dimethoxycoumarin，6,7-dimethylesculetin

6,7-Dimethoxy-2H-chromen-2-one

Scopoletin Methyl ether

Scoparone,escoparone6,7-diMethoxycouMarin

6,7-Dimethoxycoumarin,Scoparone

6,7-Dimethoxycoumarin 6,7-Dimethoxy-2H-chromen-2-one

SCOPARONE ISO 9001：2015 REACH

6,7-Dimethylesculetin (Scoparone)

TIANFU CHEM-- SCOPARONE

scoparone,escoparone6

SCOPARONE(RG) 10mg

Scoparone-RM

120-08-1

128-08-1

C11H10O4

Fluorescent Probes, Labels, Particles and Stains

Fluorescent Labels

Other Fluorescent Labels

Biochemicals and Reagents

BioChemical

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Inhibitors

Coumarins

API intermediates