(2-CHLORO-PYRIDIN-4-YL)-METHANOL

Product Name: (2-CHLORO-PYRIDIN-4-YL)-METHANOL
CAS No.: 100704-10-7
Chemical Name: (2-CHLORO-PYRIDIN-4-YL)-METHANOL
Synonyms: oro-4-pyridinyL;BUTTPARK 154\50-15;2-Chloro-4-pyridinemethanol;(2-chloro-4-pyridyl)methanol;4-Pyridinemethanol, 2-chloro-;(2-CHLORO-4-PYRIDINYL)METHANOL;2-Chloropyridine-4-methanol,97%;2-Chloro-4-pyridinemethanol >(2-CHLORO-PYRIDIN-4-YL)-METHANOL;2-CHLORO-4-HYDROXYMETHYLPYRIDINE
CBNumber: CB3487787
Molecular Formula: C6H6ClNO
Formula Weight: 143.57
MOL File: 100704-10-7.mol

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(2-CHLORO-PYRIDIN-4-YL)-METHANOL Property

Melting point:: 65.5 °C
Boiling point:: 279.0±25.0 °C(Predicted)
Density: 1.324±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 13.08±0.10(Predicted)
color: White to Light yellow
λmax: 262nm(MeOH)(lit.)
CAS DataBase Reference: 100704-10-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-28-45
WGK Germany: 3
Hazard Note: Harmful
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 714445
Product name: (2-Chloro-4-pyridinyl)methanol
Purity: 97%
Packaging: 250mg
Price: $40.8
Updated: 2023/01/07

TCI Chemical

Product number: C2595
Product name: 2-Chloro-4-pyridinemethanol
Purity: >96.0%(GC)(T)
Packaging: 1g
Price: $159
Updated: 2024/03/01

TRC

Product number: C596193
Product name: (2-Chloropyridin-4-yl)methanol
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 024833
Product name: (2-Chloro-4-pyridinyl)methanol
Purity: 97%
Packaging: 1g
Price: $19
Updated: 2021/12/16

Matrix Scientific

Product number: 024833
Product name: (2-Chloro-4-pyridinyl)methanol
Purity: 97%
Packaging: 500mg
Price: $12
Updated: 2021/12/16

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(2-CHLORO-PYRIDIN-4-YL)-METHANOL Chemical Properties,Usage,Production

Uses

(2-chloro-4-pyridinyl)methanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Definition

ChEBI: (2-Chloro-4-pyridinyl)methanol is a member of pyridines and an organohalogen compound.

Synthesis

58481-11-1

100704-10-7

The general procedure for the synthesis of 2-chloro-4-hydroxymethylpyridine from methyl 2-chloropyridine-4-carboxylate was as follows: 2-chloropyridine-4-methanol (reference Compound No. 7-1) was prepared with reference to Example 7. Under nitrogen protection, 0.95 M hexane solution of hydrogenated diisobutylaluminum (200 mL, 190 mmol) was slowly added dropwise to a solution of anhydrous tetrahydrofuran (300 mL) containing methyl 2-chloropyridine-4-carboxylate (11 g, 62 mmol), and the reaction mixture was stirred for 2 hr. under the cooling of an ice bath. Subsequently, 1N hydrochloric acid (200 mL) was added to the reaction system and stirring was continued for 1 hour at room temperature. Upon completion of the reaction, saturated aqueous sodium bicarbonate solution (400 mL) was added to neutralize and then extracted three times with ethyl acetate (100 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent to give 8.5 g of white solid 2-chloro-4-hydroxymethylpyridine in 95% yield. The structure of the product was confirmed by 1H-NMR (500 MHz, DMSO-d6): δ 4.56 (d, J = 5.8 Hz, 2H), 5.54 (t, J = 5.8 Hz, 1H), 7.34 (d, J = 4.9 Hz, 1H), 7.41 (s, 1H), 8.34 (d, J = 4.9 Hz, 1H).

References

[1] Patent: EP1602647, 2005, A1. Location in patent: Page/Page column 48
[2] Patent: WO2008/11478, 2008, A2. Location in patent: Page/Page column 76-77
[3] Patent: WO2017/42643, 2017, A1. Location in patent: Page/Page column 25
[4] Patent: WO2006/96338, 2006, A1. Location in patent: Page/Page column 47
[5] Patent: WO2006/2383, 2006, A2. Location in patent: Page/Page column 55

(2-CHLORO-PYRIDIN-4-YL)-METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(2-CHLORO-PYRIDIN-4-YL)-METHANOL Suppliers

Americas 1 Belgium 3 CHINA 189 Europe 2 France 2 Germany 6 India 10 Japan 2 Switzerland 3 United Kingdom 11 United States 55 Global 284

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View Lastest Price from (2-CHLORO-PYRIDIN-4-YL)-METHANOL manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (2-Chloro-4-pyridinyl)Methanol 100704-10-7
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-08-11

Dideu Industries Group Limited

Product: (2-CHLORO-PYRIDIN-4-YL)-METHANOL 100704-10-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-02

Career Henan Chemical Co

Product: (2-CHLORO-PYRIDIN-4-YL)-METHANOL 100704-10-7
Price: US $500.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2018-08-04

100704-10-7, (2-CHLORO-PYRIDIN-4-YL)-METHANOLRelated Search:

3-IODO-2-PROPOXY-PYRIDINE 2-CHLOROQUINOLINE-4-CARBOXYLIC ACID 2-(CYCLOHEXYLOXY)-3-IODOPYRIDINE (2-CHLORO-PYRIDIN-4-YL)-METHANOL METHYL 2,6-DICHLOROISONICOTINATE 3-IODO-2-(2,2,2-TRIFLUORO-ETHOXY)-PYRIDINE 2-CYCLOPROPYLMETHOXY-3-IODO-PYRIDINE ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLIC ACID, 97 2-Chloro-6-methylpyridine-4-carboxylic acid 3,5-BIS(METHYLSULFONYL)ANILINE 2-ISOPROPOXY-3-IODO-PYRIDINE 2-(CYCLOPENTYLOXY)-3-IODOPYRIDINE (2-CHLORO-PYRIDIN-3-YL)-METHANOL (4-Chloro-pyridin-3-yl)-methanol (4-CHLORO-PYRIDIN-2-YL)-METHANOL (5-Chloro-pyridin-3-yl)-methanol (6-CHLORO-PYRIDIN-2-YL)-METHANOL

(2-CHLORO-PYRIDIN-4-YL)-METHANOL

(2-CHLORO-PYRIDINE-4-YL)-METHANOL

2-CHLORO-4-HYDROXYMETHYLPYRIDINE

(2-CHLORO-4-PYRIDINYL)METHANOL

BUTTPARK 154\50-15

2-Chloro-4-(hydroxymethyl)pyridine 97%

4-Pyridinemethanol,2-chloro-(6CI,9CI)

2-Chloro-4-pyridinemethanol

2-Chloropyridine-4-methanol,97%

(2-chloro-4-pyridyl)methanol

(2-chloro-4-pyridinyl)methanol(SALTDATA: FREE)

2-Chloro-4-pyridinemethanol &gt

oro-4-pyridinyL

4-Pyridinemethanol, 2-chloro-

(2-CHLORO-PYRIDIN-4-YL)-METHANOL ISO 9001：2015 REACH

100704-10-7

1450-83-7

Pyridines

PYRIDINE

pharmacetical