ChemicalBook > CAS DataBase List > Diethyl acetamidomalonate
Diethyl acetamidomalonate
- Product Name
- Diethyl acetamidomalonate
- CAS No.
- 1068-90-2
- Chemical Name
- Diethyl acetamidomalonate
- Synonyms
- Diethyl 2-acetamidomalonate;ETHYL ACETAMIDOMALONATE;DIETHYL ACETAMINOMALONATE;ACETAMIDO DIETHYL MALONATE;diethyl 2-acetamidopropanedioate;ACETAMIDOMALONIC ACID DIETHYL ESTER;2-ACETYLAMINO-MALONIC ACID DIETHYL ESTER;2-(Acetylamino)propanedioic acid diethyl ester;AA-DEM;NSC 7645
- CBNumber
- CB3491359
- Molecular Formula
- C9H15NO5
- Formula Weight
- 217.22
- MOL File
- 1068-90-2.mol
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Diethyl acetamidomalonate Property
- Melting point:
- 95-98 °C (lit.)
- Boiling point:
- 185 °C/20 mmHg (lit.)
- Density
- 1.2850 (rough estimate)
- refractive index
- 1.4640 (estimate)
- Flash point:
- 185°C/20mm
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 11.93±0.59(Predicted)
- form
- Crystalline Powder
- color
- White to light yellow
- Water Solubility
- Soluble in chloroform and methanol. Slightly soluble in water.
- BRN
- 783883
- InChIKey
- ISOLMABRZPQKOV-UHFFFAOYSA-N
- CAS DataBase Reference
- 1068-90-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Propanedioic acid, (acetylamino)-, diethyl ester(1068-90-2)
- EPA Substance Registry System
- Propanedioic acid, 2-(acetylamino)-, 1,3-diethyl ester (1068-90-2)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36-36/37/38
- Safety Statements
- 39-36-26-44
- WGK Germany
- 3
- RTECS
- OO0360000
- TSCA
- Yes
- HazardClass
- IRRITANT
- HS Code
- 29241900
- Hazardous Substances Data
- 1068-90-2(Hazardous Substances Data)
- Toxicity
- eye-rbt 500 mg/24H MLD 28ZPAK -,130,72
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P234Keep only in original container.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363Wash contaminated clothing before reuse.
P390Absorb spillage to prevent material damage.
P405Store locked up.
P406Store in corrosive resistant/… container with a resistant inner liner.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- D84601
- Product name
- Diethyl acetamidomalonate
- Purity
- 98%
- Packaging
- 25g
- Price
- $41.6
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- D84601
- Product name
- Diethyl acetamidomalonate
- Purity
- 98%
- Packaging
- 100g
- Price
- $63.4
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A0015
- Product name
- Diethyl Acetamidomalonate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $19
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A0015
- Product name
- Diethyl Acetamidomalonate
- Purity
- >98.0%(GC)
- Packaging
- 100g
- Price
- $37
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A14048
- Product name
- Diethyl acetamidomalonate, 98+%
- Packaging
- 25g
- Price
- $20.65
- Updated
- 2024/03/01
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Diethyl acetamidomalonate Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystalline powder
Uses
Diethyl 2-Acetamidomalonate, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the preparation of Novobiocin analogues as potential heat shock protein 90 inhibitors. It is also used as a important intermediates in syntheses of vitamins B1 and B6, barbiturates, non-steroidal anti-inflammatory agents, other numerous pharmaceuticals.
Safety Profile
An eye irritant. When heated todecomposition it emits toxic fumes of NOx.
Purification Methods
Crystallise the ester from *benzene/pet ether. [Beilstein 4 III 2993.]
Diethyl acetamidomalonate Preparation Products And Raw materials
Raw materials
Preparation Products
DIETHYL 2-(ACETAMINDO)-2-(2-METHYL-5-NITROBENZYL)MALONATE
Diethyl(acetylamino)((2-((bis(2-hydroxyethyl)amino)methyl)-5-nitrophenyl)methyl)propanedioate
Rebamipide
DIETHYL 2-(ACETAMIDO)-2-(2-(BROMOMETHYL)-5-NITROBENZYL)MALONATE
Diethyl(acetylamino)((2-((bis(2-chloroethyl)amino)methyl)-5-nitrophenyl)methyl)propanedioate
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Diethyl acetamidomalonate Suppliers
- Tel
- --
- Fax
- --
- leeyeseok@inxchem.com
- Country
- South Korea
- ProdList
- 165
- Advantage
- 58
- Tel
- --
- Fax
- --
- unachem@ktnet.co.kr
- Country
- South Korea
- ProdList
- 1181
- Advantage
- 30
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View Lastest Price from Diethyl acetamidomalonate manufacturers
Changde Changlian Chemical Co., Ltd.
- Product
- Diethyl acetamidomalonate 1068-90-2
- Price
- US $0.00/KG/Tin
- Min. Order
- 20KG
- Purity
- >98%
- Supply Ability
- 100 tons
- Release date
- 2020-07-15
Ningxia Jinhua Chemical Co.,Ltd
- Product
- Diethyl acetamidomalonate 1068-90-2
- Price
- US $0.00/Kg/Drum
- Min. Order
- 20KG
- Purity
- >98%
- Supply Ability
- 100 tons
- Release date
- 2020-07-15
hebei hongtan Biotechnology Co., Ltd
- Product
- Diethyl acetamidomalonate 1068-90-2
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-03-22
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