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SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9

Product Name
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9
CAS No.
206986-87-0
Chemical Name
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9
Synonyms
Sodium cholate hydrate;Sodium cholate[C6445];Sodium cholate[C1254];Cholic aicd sodiuM Salt;Cholalic acid sodium salt;SODIUM CHOLATE HYDRATE, 98 %;Sodium cholate hydrate, 99.5%;Cholic aicd sodium Salt hydrate;SODIUM CHOLATE HYDRATE, SIGMAULTRA;SODIUM CHOLATE HYDRATE, BIOCHEMIKA
CBNumber
CB3497588
Molecular Formula
C24H43NaO6
Formula Weight
450.59
MOL File
206986-87-0.mol
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SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Property

RTECS 
FZ9600000
storage temp. 
Store at RT.
solubility 
H2O: 0.1 M, clear
form 
Powder
color 
White
biological source
bovine bile
ovine bile
optical activity
[α]20/D +36±2°, c = 0.6% in ethanol (dry matter)
Water Solubility 
Soluble in water.
BRN 
3582354
InChIKey
WPVYVBXDAUNXSZ-WQYDRJRFNA-N
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Safety

Safety Statements 
24/25
WGK Germany 
3
F 
3-9
TSCA 
Yes
HS Code 
29181990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
27029
Product name
Sodium cholate hydrate
Purity
≥97.0% (dried material, NT)
Packaging
100g
Price
$213
Updated
2025/07/31
Sigma-Aldrich
Product number
27029
Product name
Sodium cholate hydrate
Purity
≥97.0% (dried material, NT)
Packaging
500g
Price
$855
Updated
2025/07/31
Sigma-Aldrich
Product number
S1702
Product name
Sodium cholate hydrate
Purity
PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production.
Packaging
100g
Price
$408
Updated
2025/07/31
Sigma-Aldrich
Product number
S1702
Product name
Sodium cholate hydrate
Purity
PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production.
Packaging
1kg
Price
$2077
Updated
2025/07/31
Sigma-Aldrich
Product number
C6445
Product name
Sodium cholate hydrate
Purity
BioXtra, ≥99%
Packaging
10g
Price
$75.5
Updated
2025/07/31
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SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Chemical Properties,Usage,Production

Uses

Biochemical solubilizing agent Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins. It is involved in the study to assess infiltration of pressurized promoter solutions in a mesoporous silica. Further, it serves as a biochemical solubilizing agent.

Uses

Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.

Uses

Non-denaturing detergent used for extraction of membrane proteins.

General Description

Sodium cholate hydrate is a non-denaturing, anionic detergent.

Biochem/physiol Actions

Reduction in 12-α hydroxylase activity leads to low levels of cholic acid in liver disease.

in vivo

Cholic acid (1% (w/w) Cholic acid-supplemented diet; p.o.; 14 days) decreases SHP (small heterodimer partner) protein expression, potentially via the upregulation of miR142-3p. Cholic acid increases CYP2D6 expression and activity[2].

Animal Model:Tg-CYP2D6 adult male mice (8 weeks of age and weighing 20–25 g)[2]
Dosage:1% (w/w) Cholic acid-supplemented diet
Administration:Oral, 14 days
Result:Decreases SHP expression and increased CYP2D6 activity.

IC 50

Human Endogenous Metabolite

SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Preparation Products And Raw materials

Raw materials

Preparation Products

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SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Suppliers

China 138 Germany 1 India 1 New Zealand 1 Poland 1 Switzerland 1 United States 9 Global 152
Henan yingchuang
Tel
16650708709
Fax
qq:778660296
Email
hnyingchuang@163.com
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China
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3965
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58
Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
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Adamas Reagent, Ltd.
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400-6009262 16621234537
Fax
021-64823266
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chenyj@titansci.com
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China
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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3007715519@qq.com
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China
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18729
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Sichuan Kulinan Technology Co., Ltd
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400-1166-196 18981987031
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028-84555506 800101999
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cdhxsj@163.com
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China
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Tianjin heowns Biochemical Technology Co., Ltd.
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400 638 7771
Email
sales@heowns.com
Country
China
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14435
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57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
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62
ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4999
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View Lastest Price from SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 manufacturers

Wuhan Boyuan Import & Export Co., LTD
Product
Sodium cholate hydrate 206986-87-0
Price
US $23.00-16.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
75000kg/month
Release date
2023-03-08
Hebei Fengqiang Trading Co., LTD
Product
sodium cholate hydrate 206986-87-0
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-05
Career Henan Chemical Co
Product
SODIUM CHOLATE HYDRATE, BIOCHEMIKA 206986-87-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-09

206986-87-0, SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9Related Search:

Sodium Palmitate LITHOCHOLIC ACID sodium docosanoate Ursodeoxycholic acid Sodium octanoate 2,7-Decahydronaphthalenediol CAPRIC ACID SODIUM SALT LAURIC ACID SODIUM SALT Sodium stearate Sodium deoxycholate PELARGONIC ACID SODIUM SALT 12-HYDROXYDODECANOIC ACID CHOLANIC ACID SODIUM MYRISTATE 16-HYDROXYHEXADECANOIC ACID ENANTHIC ACID SODIUM SALT DEOXYCHOLIC ACID SODIUM SALT MONOHYDRATE Glycochenodeoxycholic acid sodium salt

  • SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9
  • 3,7,12-trihydroxy-, monosodium salt
  • 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt
  • Cholalic acid sodium salt
  • SODIUM CHOLATE HYDRATE, 98 %
  • SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 96.0% NT DRY MATTER
  • SODIUM CHOLATE HYDRATE, CELL CULTURE TESTED
  • SODIUM CHOLATE HYDRATE, PURUM, >= 97.0% NT DRIED MATERIAL
  • SODIUM CHOLATE HYDRATE, SIGMAULTRA
  • SODIUM CHOLATE HYDRATE FROM OX OR SHEEP BILE
  • Cholalic acid sodium salt, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt
  • Sodium cholate hydrate,3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt
  • Cholic aicd sodiuM Salt
  • (3alpha,5alpha,7alpha,12alpha)-3,7,12-Trihydroxycholan-24-oic acid monosodium salt hydrate
  • Sodium cholate hydrate
  • SODIUM CHOLATE HYDRATE, BIOCHEMIKA
  • 3α,7α,12α-Trihydroxy-5β-cholanic acid sodium salt hydrate
  • SODIUM CHOLATE HYDRATE BIOXTRA, >= 9
  • SODIUM CHOLATE HYDRATE, >= 97.0 % NT
  • SODIUM CHOLATE HYDRATE, FROM OX AND/
  • Sodium cholate hydrate, 99.5%
  • Cholic aicd sodium Salt hydrate
  • α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt
  • sodium,(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate,hydrate
  • Cholalic acid sodium salt xhydrate
  • SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9,NA
  • Sodium cholate[C6445]
  • Sodium cholate[C1254]
  • 206986-87-0
  • C24H41NaO6
  • C24H39NaO5xH2O
  • C24H39O5Na