ChemicalBook > CAS DataBase List > TRAM-34

TRAM-34

Product Name
TRAM-34
CAS No.
289905-88-0
Chemical Name
TRAM-34
Synonyms
RAM-34;CS-1574;TRAM34;TRAM 34;Triarylmethane-34;TRAM-34 USP/EP/BP;Clotrimazole Impurity 8;Des Imidazole 1-pyrazole;Clotrimazole TRAM-34 Impurity;TRAM34;TRAM 34;TRIARYLMETHANE-34;1-[(2-Chlorophenyl)diphenylmethyl]-
CBNumber
CB3505056
Molecular Formula
C22H17ClN2
Formula Weight
344.84
MOL File
289905-88-0.mol
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TRAM-34 Property

Melting point:
145-147°C
storage temp. 
2-8°C
solubility 
DMSO: ~11 mg/mL
form 
solid
color 
off-white
Water Solubility 
Soluble in DMSO at 2mg/ml. Insoluble in water
CAS DataBase Reference
289905-88-0
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T6700
Product name
TRAM 34
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$194
Updated
2024/03/01
Sigma-Aldrich
Product number
T6700
Product name
TRAM 34
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$610
Updated
2024/03/01
Alfa Aesar
Product number
J60019
Product name
TRAM 34
Packaging
25mg
Price
$286
Updated
2023/06/20
Cayman Chemical
Product number
23385
Product name
TRAM 34
Purity
≥98%
Packaging
5mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
23385
Product name
TRAM 34
Purity
≥98%
Packaging
10mg
Price
$68
Updated
2024/03/01
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TRAM-34 Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Definition

ChEBI: TRAM-34 is an organochlorine compound.

Biological Activity

Highly selective blocker of intermediate conductance Ca 2+ -activated K + channels (IK Ca 1, K Ca 3.1) (K d = 20 nM). Exhibits 200-1500-fold selectivity over K V , BK Ca , SK Ca , Na + , CRAC and Cl - channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.

Biochem/physiol Actions

TRAM-34 exhibits 100-fold selectivity (Kd = 20 nM) for IKCa1 channels over other K+ channels (Charybdotoxin, Kd = 5 nM, Clotrimazole, Kd = 70 nM; Nitrendipine Kd = 900 nM). Furthermore, TRAM-34 is known to suppress the activation of human T lymphocytes,.

storage

+4°C

TRAM-34 Preparation Products And Raw materials

Raw materials

Preparation Products

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TRAM-34 Suppliers

Alfa Chemistry
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View Lastest Price from TRAM-34 manufacturers

Career Henan Chemical Co
Product
TRAM-34 289905-88-0
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-30

289905-88-0, TRAM-34Related Search:


  • CS-1574
  • TRAM34;TRAM 34
  • 1-[(2-chlorophenyl)-diphenylmethyl]pyrazole
  • Clotrimazole TRAM-34 Impurity
  • Triarylmethane-34
  • Clotrimazole Impurity 8
  • TRAM34;TRAM 34;TRIARYLMETHANE-34
  • 1-[(2-Chlorophenyl)diphenylmethyl]-
  • 1H-Pyrazole, 1-[(2-chlorophenyl)diphenylmethyl]-
  • TRAM-34 USP/EP/BP
  • 4-chloro-2,3-dihydro-1H-indene-6-carboxylicacid
  • Carbonochloridicacid,9-methylphenylester
  • RAM-34
  • TRAM34,Inhibitor,Potassium Channel,KcsA,inhibit,TRAM-34
  • Des Imidazole 1-pyrazole
  • 289905-88-0
  • Heterocyclic Compounds
  • Heterocycles
  • Inhibitors