VH 032 phenol-linker 1

Product Name: VH 032 phenol-linker 1
CAS No.: 2376990-26-8
Chemical Name: VH 032 phenol-linker 1
Synonyms: VH 032 phenol-linker 1;VH 032 phenol-alkylC4-amine;VH 032 phenol-alkylC4-amine dihydrochloride;(S,R,S)-AHPC-phenol-C4-NH2 (dihydrochloride);(2S,4R)-1-[(S)-2-Acetamido-3,3-dimethylbutanoyl]-N-[2-(4-aminobutoxy)-4-(4-methyl-5-thiazolyl)benzyl]-4-hydroxypyrrolidine-2-carboxamide Dihydrochloride;(2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-(4-aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
CBNumber: CB35985172
Molecular Formula: C28H42ClN5O5S
Formula Weight: 596.18
MOL File: 2376990-26-8.mol

More

Less

VH 032 phenol-linker 1 Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 6909
Product name: VH032phenol-alkylC4-amine
Purity: ≥95%(HPLC)
Packaging: 25
Price: $367
Updated: 2021/12/16

More

Less

VH 032 phenol-linker 1 Chemical Properties,Usage,Production

Uses

(S,R,S)-AHPC-phenol-C4-NH2 (VH032-phenol-C4-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC?based VHL ligand and a linker used in?PROTAC?technology[1].

storage

Store at -20°C

References

[1] Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery.?Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. DOI:10.1016/j.csbj.2019.01.006
[2] [3].Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

VH 032 phenol-linker 1 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

VH 032 phenol-linker 1 Suppliers

China 14 United States 2 Global 16

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1615
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 55000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-025-66113011 18626450290
Email: cb5@aikonchem.com
Country: China
ProdList: 10358
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: SY06@accelachem.com
Country: China
ProdList: 7514
Advantage: 58

2376990-26-8, VH 032 phenol-linker 1Related Search:

VH032 thiol E3 ligase Ligand-Linker Conjugates 29 HaloPROTAC 2 VH 101, phenol (2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

VH 032 phenol-linker 1

VH 032 phenol-alkylC4-amine

(S,R,S)-AHPC-phenol-C4-NH2 (dihydrochloride)

VH 032 phenol-alkylC4-amine dihydrochloride

(2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-(4-aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride

(2S,4R)-1-[(S)-2-Acetamido-3,3-dimethylbutanoyl]-N-[2-(4-aminobutoxy)-4-(4-methyl-5-thiazolyl)benzyl]-4-hydroxypyrrolidine-2-carboxamide Dihydrochloride

2376990-26-8