ChemicalBook > CAS DataBase List > VH 101, phenol
VH 101, phenol
- Product Name
- VH 101, phenol
- CAS No.
- 2306193-99-5
- Chemical Name
- VH 101, phenol
- Synonyms
- Phenolic VH101;VH 101, phenol;E3 ligase Ligand 19;VH032-cyclopropane-F;VH032-cyclopropane-F, 10 mM in DMSO;(2S,4R)-1-((S)-2-(1-fluorocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;Inhibitor,E3 ligase-recruiting Moiety,inhibit,VHL ligand3,Ligands for E3 Ligase,VH032 cyclopropane F,VH032cyclopropaneF,VHL ligand-3,VH-032-cyclopropane-F;(2S,4R)-1-((S)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-[(2S)-2-[(1-fluorocyclopropyl)formamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
- CBNumber
- CB05965564
- Molecular Formula
- C26H33FN4O5S
- Formula Weight
- 532.63
- MOL File
- 2306193-99-5.mol
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VH 101, phenol Property
- Boiling point:
- 841.7±65.0 °C(Predicted)
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO
- pka
- 9.12±0.35(Predicted)
- form
- Solid
- color
- White to yellow
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N-Bromosuccinimide Price
Tocris
- Product number
- 6952
- Product name
- VH101,phenol
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $669
- Updated
- 2021/12/16
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VH 101, phenol Chemical Properties,Usage,Production
Uses
VH032-cyclopropane-F (VH 101, phenol) is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal hydroxyl group. Allows rapid conjugation with many linkers containing active leaving groups. A basic building block for development of a protein degrader library.
reaction suitability
reagent type: ligand
IC 50
VHL
storage
Store at +4°C
VH 101, phenol Preparation Products And Raw materials
Raw materials
Preparation Products
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2306193-99-5, VH 101, phenolRelated Search:
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VH 032 phenol-linker 1
(2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
VH032 thiol
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