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ACES

Product Name
ACES
CAS No.
7365-82-4
Chemical Name
ACES
Synonyms
ACES;ACES BUFFER;N-(2-ACETAMIDO)-2-AMINOETHANESULFONIC ACID;ACEC;ACES, VETEC;ACES, BIOGRADE;ACES, 96%, PURE;ACES SIGMAULTRA;ACES, pure, 96%;TIMTEC-BB SBB006711
CBNumber
CB3663938
Molecular Formula
C4H10N2O4S
Formula Weight
182.2
MOL File
7365-82-4.mol
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ACES Property

Melting point:
>220 °C (dec.)(lit.)
Boiling point:
404.49℃
Density 
1.484±0.06 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
room temp
solubility 
H2O: 0.1 M at 20 °C, clear, colorless
form 
Crystals
color 
White
PH Range
6.1 - 7.5
PH
2.5-4.5 (25℃, 0.1M in H2O)
pka
6.8(at 25℃)
Water Solubility 
soluble
λmax
λ: 260 nm Amax: 0.008
λ: 280 nm Amax: 0.005
Merck 
14,36
BRN 
2253770
InChIKey
DBXNUXBLKRLWFA-UHFFFAOYSA-N
LogP
-4.49 at 25℃
CAS DataBase Reference
7365-82-4(CAS DataBase Reference)
EPA Substance Registry System
Ethanesulfonic acid, 2-[(2-amino-2-oxoethyl)amino]- (7365-82-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29241900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A3594
Product name
ACES
Purity
BioPerformance Certified, ≥99.0%
Packaging
1kg
Price
$1188
Updated
2024/03/01
Sigma-Aldrich
Product number
00194
Product name
ACES
Purity
BioUltra, ≥99.5% (T)
Packaging
100g
Price
$558
Updated
2024/03/01
Sigma-Aldrich
Product number
RES1000A-A7
Product name
ACES
Purity
PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture
Packaging
1pkg
Price
$245
Updated
2022/05/15
TCI Chemical
Product number
A0700
Product name
N-(2-Acetamido)-2-aminoethanesulfonic Acid [Good's buffer component for biological research]
Purity
>99.0%(T)
Packaging
25g
Price
$50
Updated
2024/03/01
Alfa Aesar
Product number
A11553
Product name
ACES, 99%
Packaging
25g
Price
$44.65
Updated
2024/03/01
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ACES Chemical Properties,Usage,Production

Description

ACES is a zwitterionic buffering agent used in biochemistry and molecular biology that was first selected and described by Good et al. It is a paraacetamide buffer suitable for environments with a pH of 6.1 - 7.5. ACES can be used as a buffer component in cell culture media for use in agarose and polyacrylamide electrophoresis and in isoelectric focusing of proteins. It forms complexes with most common metals, and the formation constant should be taken into account when using such buffers in solutions containing metal ions.

Chemical Properties

ACES (N-(Carbamoylmethyl)taurine) is white crystals

Uses

ACES is used as a Good's buffer is an ideal separator in the resolution of protein systems, a zwitterionic compound used in biochemical and biological research.

Uses

N-(Carbamoylmethyl)taurine can be used to study biological buffers and zwitterionic compounds. ACES has been used in a study to determine the levels of ibuprofen and flurbiprofen in pharmaceuticals by capillary zone electrophoresis.

Uses

Buffer for biological systems.

Definition

ChEBI: ACES (N-(2-acetamido)-2-aminoethanesulfonic acid) is a Good's buffer substance, pKa = 6.9 at 20 ℃. It is an ACES and an amino sulfonic acid. It is a tautomer of a 2-[(2-amino-2-oxoethyl)ammonio]ethanesulfonate.

Preparation

In the presence of the reaction solvent tetrahydrofuran, add nitrogen-containing reagent ammonia into the reactor to react with the raw material, wherein the molar ratio of ammonia to theraw material is 1:1. The reaction temperature is 60°C, the reaction pressure is 1 MPa (gauge pressure), and the reaction time is 8 hours. After the reaction is completed, it is acidified to generate ACES. Then spin off the solvent tetrahydrofuran, add ethyl acetate, wash twice with water, dry with anhydrous sodium sulfate, and spin off the ethyl acetate to obtain the crude ACES. Purification stepIn the reactor, the purified solvent tetrahydrofuran was added to dissolve the crude ACES, recrystallized at low temperature, the insoluble matter was removed by suction, and the filtrate was rotary evaporated to remove tetrahydrofuran to obtain refined ACES.

Purification Methods

Recrystallise ACES from hot aqueous EtOH. [Perrin & Dempsey Buffers for pH and Metal Ion Control Chapman & Hall, London 1974, Beilstein 4 III 1707.]

ACES Preparation Products And Raw materials

Raw materials

Preparation Products

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ACES Suppliers

Hu' nan Yunbang Pharmaceutical Co., Ltd.
Tel
0731-85561037 15386497078
Email
yunbang@yunbangapi.com
Country
China
ProdList
4828
Advantage
58
Hunan Hengfei bio-pharmaceutical Co. , Ltd.
Tel
0746-6222194 13874779848
Fax
0746-6222194
Email
57182844@qq.com
Country
China
ProdList
86
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Nanjing Search Biotech Co., Ltd
Tel
+86-025-81682922 +86-13515111588
Fax
025-85860962
Email
sales@searchbio.com.cn
Country
China
ProdList
135
Advantage
68
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
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View Lastest Price from ACES manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
N-(Carbamoylmethyl)taurine(ACES) 7365-82-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-04
WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-(Carbamoylmethyl)taurine 7365-82-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
3500kg/month
Release date
2021-09-09
Hebei Yanxi Chemical Co., Ltd.
Product
N-(Carbamoylmethyl)taurine 7365-82-4
Price
US $30.00-26.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-09-14

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