ChemicalBook > CAS DataBase List > ACES

ACES

Product Name
ACES
CAS No.
7365-82-4
Chemical Name
ACES
Synonyms
ACES;ACES BUFFER;N-(2-ACETAMIDO)-2-AMINOETHANESULFONIC ACID;ACEC;ACES, VETEC;ACES, BIOGRADE;ACES, 96%, PURE;ACES SIGMAULTRA;ACES, pure, 96%;TIMTEC-BB SBB006711
CBNumber
CB3663938
Molecular Formula
C4H10N2O4S
Formula Weight
182.2
MOL File
7365-82-4.mol
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ACES Property

Melting point:
>220 °C (dec.)(lit.)
Boiling point:
404.49℃
Density 
1.484±0.06 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
room temp
solubility 
H2O: 0.1 M at 20 °C, clear, colorless
form 
Crystals
color 
White
PH Range
6.1 - 7.5
PH
2.5-4.5 (25℃, 0.1M in H2O)
pka
6.8(at 25℃)
Water Solubility 
soluble
λmax
λ: 260 nm Amax: 0.008
λ: 280 nm Amax: 0.005
Merck 
14,36
BRN 
2253770
InChIKey
DBXNUXBLKRLWFA-UHFFFAOYSA-N
LogP
-4.49 at 25℃
CAS DataBase Reference
7365-82-4(CAS DataBase Reference)
EPA Substance Registry System
Ethanesulfonic acid, 2-[(2-amino-2-oxoethyl)amino]- (7365-82-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29241900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A3594
Product name
ACES
Purity
BioPerformance Certified, ≥99.0%
Packaging
1kg
Price
$1188
Updated
2024/03/01
Sigma-Aldrich
Product number
00194
Product name
ACES
Purity
BioUltra, ≥99.5% (T)
Packaging
100g
Price
$558
Updated
2024/03/01
Sigma-Aldrich
Product number
RES1000A-A7
Product name
ACES
Purity
PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture
Packaging
1pkg
Price
$245
Updated
2022/05/15
TCI Chemical
Product number
A0700
Product name
N-(2-Acetamido)-2-aminoethanesulfonic Acid [Good's buffer component for biological research]
Purity
>99.0%(T)
Packaging
25g
Price
$50
Updated
2024/03/01
Alfa Aesar
Product number
A11553
Product name
ACES, 99%
Packaging
25g
Price
$44.65
Updated
2024/03/01
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ACES Chemical Properties,Usage,Production

Description

ACES is a zwitterionic buffering agent used in biochemistry and molecular biology that was first selected and described by Good et al. It is a paraacetamide buffer suitable for environments with a pH of 6.1 - 7.5. ACES can be used as a buffer component in cell culture media for use in agarose and polyacrylamide electrophoresis and in isoelectric focusing of proteins. It forms complexes with most common metals, and the formation constant should be taken into account when using such buffers in solutions containing metal ions.

Chemical Properties

ACES (N-(Carbamoylmethyl)taurine) is white crystals

Uses

ACES is used as a Good's buffer is an ideal separator in the resolution of protein systems, a zwitterionic compound used in biochemical and biological research.

Uses

N-(Carbamoylmethyl)taurine can be used to study biological buffers and zwitterionic compounds. ACES has been used in a study to determine the levels of ibuprofen and flurbiprofen in pharmaceuticals by capillary zone electrophoresis.

Uses

Buffer for biological systems.

Definition

ChEBI: ACES (N-(2-acetamido)-2-aminoethanesulfonic acid) is a Good's buffer substance, pKa = 6.9 at 20 ℃. It is an ACES and an amino sulfonic acid. It is a tautomer of a 2-[(2-amino-2-oxoethyl)ammonio]ethanesulfonate.

Preparation

In the presence of the reaction solvent tetrahydrofuran, add nitrogen-containing reagent ammonia into the reactor to react with the raw material, wherein the molar ratio of ammonia to theraw material is 1:1. The reaction temperature is 60°C, the reaction pressure is 1 MPa (gauge pressure), and the reaction time is 8 hours. After the reaction is completed, it is acidified to generate ACES. Then spin off the solvent tetrahydrofuran, add ethyl acetate, wash twice with water, dry with anhydrous sodium sulfate, and spin off the ethyl acetate to obtain the crude ACES. Purification stepIn the reactor, the purified solvent tetrahydrofuran was added to dissolve the crude ACES, recrystallized at low temperature, the insoluble matter was removed by suction, and the filtrate was rotary evaporated to remove tetrahydrofuran to obtain refined ACES.

Purification Methods

Recrystallise ACES from hot aqueous EtOH. [Perrin & Dempsey Buffers for pH and Metal Ion Control Chapman & Hall, London 1974, Beilstein 4 III 1707.]

ACES Preparation Products And Raw materials

Raw materials

Preparation Products

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ACES Suppliers

Americas 1 Belgium 2 Canada 2 China 254 Czech Republic 1 Europe 4 France 1 Germany 11 India 27 Japan 6 Poland 1 South Korea 2 Switzerland 3 The Netherlands 1 United Kingdom 22 United States 47 Global 385
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View Lastest Price from ACES manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
N-(2-acetamido)-2-aminoethanesulfonic acid 7365-82-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99.91%
Supply Ability
200000
Release date
2024-04-25
Suzhou Genemill Biotechnology Co.,Ltd
Product
ACES 7365-82-4
Price
US $1.00/Kg
Min. Order
1Kg
Purity
0.995
Supply Ability
1000tons
Release date
2023-09-14
Suzhou Genemill Biotechnology Co.,Ltd
Product
ACES-N-(2-Acetamido)-2-aminoethanesulfonic Acid 7365-82-4
Price
US $1.00/Kg
Min. Order
1Kg
Purity
0.995
Supply Ability
1000tons
Release date
2023-10-23

7365-82-4, ACESRelated Search:

Sulfamic acid Glycine Acetaminophen N-Acetylsulfanilyl chloride Taurine 2-ACETAMIDOFLUORENE ALTRENOGEST Molasses Glycinamide Sodium N-cyclohexylsulfamate cefsulodin sodium salt Sulbenicillin sodium Ethanesulfonic acid SULBENICILLIN ACETAMINOPHENOL BP/USP ACES POTASSIUM SALT ACES AMINO ACIDS

  • N-(2-ACETAMIDO)-2-AMINOETHANESULFONIC ACID
  • N-(2-ACETAMIDO)-2-AMINOETHANESULPHONIC ACID
  • N-(CARBAMOYLMETHYL)TAURINE
  • N-(CARBAMOYLMETHYL)-2-AMINOETHANESULFONIC ACID
  • TIMTEC-BB SBB006711
  • ACES
  • ACES BUFFER
  • ACES,BIOLOGICALBUFFER
  • N-(2-Acetamido)-2-aminoethanesulphonic acid >99%
  • N-(2-Acetamido)-2-aminoethanesulfonic Acid [Good's buffer component for biological research]
  • ACES, 99%, EXTRA PURE
  • ACES, 96%, PURE
  • ACES, for biochemistry
  • ACES,99+%,for biochemistry
  • N-[(2-Amino-2-oxoethyl)amino]ethanesulfonic acid
  • N-(2-Acemido)-2-aminoethanesulfonic Acid
  • N-(2-Acetamido)-2-am
  • 2-[[2-AMINO-2-OXOETHYLAMINO]ETHANE] SULPHONIC ACID
  • N-(2-Acetamido)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)taurine
  • N-(2-AcetaMido)-2-aMinoethanesulfonic Acid&nbsp
  • N-(CarbaMoylMethyl)taurine (ACES)
  • ACES 2-[(Carbamoylmethyl)amino]ethanesulfonic Acid
  • N-(Carbamoylmethyl)taurine 2-[(2-Amino-2-oxoethyl)amino]ethanesulfonic acid
  • POTASSIUM HYDROXIDE 0,1MOL/L DUTY PAID
  • ACES Vetec(TM) reagent grade, 98%
  • NITROBLUE TETRAZOLIUM CHLORIDE ULTRAPURE
  • 2-(CARBAMOYLMETHYLAMINO)ETHANESULFONIC ACID
  • 2-[(2-AMINO-2-OXOETHYL)AMINO]ETHANESULFONIC ACID
  • LABOTEST-BB LT00012617
  • 2-[(2-amino-2-oxoethyl)amino]-ethanesulfonicaci
  • ACES, BIOTECHNOLOGY PERFORMANCE CERTIFIE D
  • ACES SIGMAULTRA
  • ACES, 99% (N-(2-ACETAMIDO)-2-AMINOETHANE -SULFONIC ACID)
  • N-(2-ACETAMIDO)-2-AMINOETHANESULFONIC ACID BUFFER SUBSTANCE ACES
  • ACES, BIOGRADE
  • ACES 2-[(2-AMINO-2-OXYETHYL) AMINO] ETHANE SULFONIC ACID N-(2-ACETAMIDO)-2-AMINOETHANE SULFONIC ACID) HIGH PURITY GRADE
  • N-(2-ACETAMIDO0-2-AMINOETHANESULFONIC ACID
  • AcesN-(2-Acetamido)-2-AminoethanesulfonicAcid
  • Aces(2-[(2-Amino-2-Oxoethyl)Amino]EthanesulfonicAcid)
  • N-(2-ACETAMIDO)-2-AMINOETHANESULFONIC ACID ACES
  • ACES, MOLECULAR BIOLOGY GRADE
  • ACES, extra pure, 99%
  • N-(2-Acetamido)-2-aminoethanesulfonic acid; N-(Carbamoylmethyl)taurine
  • ACES, for biochemistry, 99+%
  • ACES, pure, 96%
  • N-(2-Acetamido)-2-Aminoethanes
  • Ethanesulfonic acid, 2-(2-amino-2-oxoethyl)amino-
  • ACES, BIOPERFORMANCE CERTIFIED&
  • ACES, VETEC
  • ACES, N-(Carbamoylmethyl)-2-aminoethane sulfonic acid
  • N-(2-Acetamido)-2-aminoethanesulfonic Acid [Good's buffer component for biological research]&gt
  • N-(2-acetamido)-2-aminoethanesulfonicaci
  • N-(Carbamoylmethyl)taurine ISO 9001：2015 REACH
  • N-(Carbamoylmethyl)
  • ACES Buffer extrapure, 99%
  • ACEC
  • N-(2-Acetamido)-2-aminoethanesulfonic acid sodium salt
  • 7365-82-4