ChemicalBook > CAS DataBase List > BISNORCHOLENALDEHYDE

BISNORCHOLENALDEHYDE

Product Name
BISNORCHOLENALDEHYDE
CAS No.
3986-89-8
Chemical Name
BISNORCHOLENALDEHYDE
Synonyms
BNKY018-PG01;Bisnorcholeldehyde;KETOBISNORALDEHYDE;Bisnorcholenaldehyde;Progesterone Impurity 7;Progesterone Impurity 24;Progesterone EP Impurity I;Didroprogesterone impurity 2;Progesterone EP Impurity I-02;(20S)-20-Formylpregn-4-en-3-one
CBNumber
CB3670455
Molecular Formula
C22H32O2
Formula Weight
328.49
MOL File
Mol file
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BISNORCHOLENALDEHYDE Property

Melting point:
159-160 °C
Boiling point:
459.4±14.0 °C(Predicted)
Density 
1.07±0.1 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H351Suspected of causing cancer

H360May damage fertility or the unborn child

H362May cause harm to breast-fed children

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

J&W Pharmlab
Product number
99R0035
Product name
Bisnorcholenaldehyde
Purity
99%
Packaging
250mg
Price
$150
Updated
2021/12/16
J&W Pharmlab
Product number
99R0035
Product name
Bisnorcholenaldehyde
Purity
99%
Packaging
1g
Price
$500
Updated
2021/12/16
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BISNORCHOLENALDEHYDE Chemical Properties,Usage,Production

Description

Androstenedione is the main product after phytosterol fermentation by Mycobacteria. Bisnorcholenaldehyde (BA; 3-Oxopregn-4-ene-20-carboxaldehyde) is one of the by-products produced during fermentation. Bisnorcholenaldehyde is an essential intermediate in the production of progesterone, which is used to treat threatened abortion or habitual abortion disease caused by luteal insufficiency. It is a precursor of androgen, estrogen, glucocorticoid and intermediates of steroid hormone synthesis[1]. In addition, BA is used in magnetic-based graphene composites with steroidal diamine dimer as a potential drug in hyperthermia cancer therapy.

Uses

Bisnorcholenaldehyde is hydrocarbon derivatives and can be used as reference materials for medical impurities.

References

[1] Shi-Dong Xu. “Refining androstenedione and bisnorcholenaldehyde from mother liquor of phytosterol fermentation using macroporous resin column chromatography followed by crystallization.” Journal of Chromatography B 1079 (2018): Pages 9-14.

BISNORCHOLENALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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BISNORCHOLENALDEHYDE Suppliers

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3986-89-8, BISNORCHOLENALDEHYDERelated Search:


  • KETOBISNORALDEHYDE
  • 3-KETO-4-PREGNENE-20-BETA-CARBOXALDEHYDE
  • 4-PREGNEN-20BETA-CARBOXALDEHYDE-3-ONE
  • 4-PREGNEN-3-ONE-20-BETA-CARBOXALDEHYDE
  • Progesterone EP Impurity I
  • Progesterone Impurity 7
  • Progesterone EP Impurity I (S-isomer)
  • (20S)-3-oxopregn-4-ene-20-carboxaldehyde
  • BNKY018-PG01
  • Bisnorcholeldehyde
  • Pregn-4-ene-20-carboxaldehyde, 3-oxo-, (20S)-
  • (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal
  • 3-Oxo-pregn-4-ene-20α- carboxaldehyde
  • Progesterone Impurity 24
  • (20S)-20-Formylpregn-4-en-3-one
  • (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal (Progesterone Impurity)
  • Didroprogesterone impurity 2
  • Progesterone EP Impurity I-02
  • Bisnorcholenaldehyde
  • 3986-89-8