5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN
- Product Name
- 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN
- CAS No.
- 150347-59-4
- Chemical Name
- 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN
- Synonyms
- CFSE;CFDA SE;NHS ester;≥90% (HPCE);5(6)-FAM DA SE;CFSE (CFDA-SE);-Cellstain-Cfse;5-FAM-NHS DIACETATE;CFSE, 10 mM in DMSO;5(6)-CFDA N-succinmidyl este
- CBNumber
- CB3672464
- Molecular Formula
- C29H19NO11
- Formula Weight
- 557.46
- MOL File
- 150347-59-4.mol
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN Property
- Melting point:
- 152-154 °C(lit.)
- storage temp.
- -20°C
- solubility
- DMF: soluble
- pka
- 6.45(at 25℃)
- form
- Solid
- color
- Off-white to yellow
- Appearance
- white solid
- PH Range
- Weak green ' uorescence (6.0) to strong green ' uorescence (7.2)
- λmax
- <300nm
- Major Application
- Diagnosis of cancer, restricting HIV replication, antiinflammatory agent, detecting bacteria, cell proliferation assays
- InChIKey
- QSWYNOQSGMUDQZ-UHFFFAOYSA-N
- SMILES
- C12(OC(=O)C3=CC(C(=O)ON4C(=O)CCC4=O)=CC=C13)C1C=CC(OC(=O)C)=CC=1OC1C=C(OC(=O)C)C=CC2=1
Safety
- WGK Germany
- 3
- F
- 8-10-21
- HS Code
- 32129000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 21888
- Product name
- 5(6)-Carboxyfluorescein diacetate N-succinimidyl ester
- Purity
- BioReagent, suitable for fluorescence, ≥90% (HPLC)
- Packaging
- 25mg
- Price
- $396
- Updated
- 2025/07/31
- Product number
- 21888
- Product name
- 5(6)-Carboxyfluorescein diacetate N-succinimidyl ester
- Purity
- BioReagent, suitable for fluorescence, ≥90% (HPLC)
- Packaging
- 100mg
- Price
- $1110
- Updated
- 2025/07/31
- Product number
- 14456
- Product name
- CFDA-SE
- Purity
- ≥90%
- Packaging
- 10mg
- Price
- $77
- Updated
- 2024/03/01
- Product number
- 14456
- Product name
- CFDA-SE
- Purity
- ≥90%
- Packaging
- 25mg
- Price
- $162
- Updated
- 2024/03/01
- Product number
- 14456
- Product name
- CFDA-SE
- Purity
- ≥90%
- Packaging
- 50mg
- Price
- $284
- Updated
- 2024/03/01
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN Chemical Properties,Usage,Production
Description
(5,6)-FAM diacetate NHS ester is a cell-permeable amine-reactive label for biomolecules.
This molecule is non-fluorescent until the acetate groups are cleaved by intracellular esterases resulting in the formation of a highly fluorescent fluorophore with emission in the green spectrum range (absorption maximum at ~492 nm, emission maximum at ~517 nm). Due to this characteristic, this product is used for tracking cells and flow cytometric evaluations and studying intracellular esterase.
Chemical Properties
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN is Off-white to light yellow powder
Uses
Amine-reactive succinimidyl ester can potentially be used for long-term pH studies of live cells, producing a conjugate with the pH-sensitive properties of carboxyfluorescein.
Uses
A 5(6)-Carboxyfluorescein (C178215) derivative used as a flurorescent probe. 5(6)-Carboxyfluorescein 3’,6’-Diacetate N-Succinimidyl Ester is used to monitor lymphocyte proliferation by covalently labelling long-lived intracellular molecules with fluorescent dye.
Uses
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN is a Non-fluorescent cell permeant amine-reactive probe for long term tracing of cell.
General Description
5-(and-6)-Carboxyfluorescein diacetate N-succinimidyl ester (CFSE) is a fluorescent dye, which is membrane permeable. It labels cells by covalently binding to intracellular molecules. CFSE is used to track lymphocyte migration and proliferation.
Biochem/physiol Actions
5(6)-Carboxyfluorescein diacetate N-succinimidyl ester is used as an indicator for esterase activity.
Abs/Em Maxima
492/517 nm
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN manufacturers
- Product
- 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN 150347-59-4
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 90%
- Supply Ability
- 100KG
- Release date
- 2020-01-29