ChemicalBook > CAS DataBase List > 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN

5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN

Product Name
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN
CAS No.
150347-59-4
Chemical Name
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN
Synonyms
CFSE;CFDA SE;NHS ester;≥90% (HPCE);5(6)-FAM DA SE;CFSE (CFDA-SE);-Cellstain-Cfse;5-FAM-NHS DIACETATE;5(6)-CFDA N-succinmidyl este;5(6)-CFDA N-succinmidyl ester
CBNumber
CB3672464
Molecular Formula
C29H19NO11
Formula Weight
557.46
MOL File
150347-59-4.mol
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5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN Property

Melting point:
152-154 °C(lit.)
storage temp. 
-20°C
solubility 
DMF: soluble
pka
6.45(at 25℃)
form 
Solid
color 
Off-white to yellow
PH Range
Weak green ' uorescence (6.0) to strong green ' uorescence (7.2)
λmax
<300nm
Major Application
Diagnosis of cancer, restricting HIV replication, antiinflammatory agent, detecting bacteria, cell proliferation assays
InChIKey
QSWYNOQSGMUDQZ-UHFFFAOYSA-N
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Safety

WGK Germany 
3
F 
8-10-21
HS Code 
32129000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
21888
Product name
5(6)-Carboxyfluorescein diacetate N-succinimidyl ester
Purity
BioReagent, suitable for fluorescence, ≥90% (HPLC)
Packaging
25mg
Price
$382
Updated
2024/03/01
Sigma-Aldrich
Product number
21888
Product name
5(6)-Carboxyfluorescein diacetate N-succinimidyl ester
Purity
BioReagent, suitable for fluorescence, ≥90% (HPLC)
Packaging
100mg
Price
$1070
Updated
2024/03/01
Cayman Chemical
Product number
14456
Product name
CFDA-SE
Purity
≥90%
Packaging
10mg
Price
$77
Updated
2024/03/01
Cayman Chemical
Product number
14456
Product name
CFDA-SE
Purity
≥90%
Packaging
25mg
Price
$162
Updated
2024/03/01
Cayman Chemical
Product number
14456
Product name
CFDA-SE
Purity
≥90%
Packaging
50mg
Price
$284
Updated
2024/03/01
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5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN Chemical Properties,Usage,Production

Chemical Properties

5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN is Off-white to light yellow powder

Uses

Amine-reactive succinimidyl ester can potentially be used for long-term pH studies of live cells, producing a conjugate with the pH-sensitive properties of carboxyfluorescein.

Uses

A 5(6)-Carboxyfluorescein (C178215) derivative used as a flurorescent probe. 5(6)-Carboxyfluorescein 3’,6’-Diacetate N-Succinimidyl Ester is used to monitor lymphocyte proliferation by covalently labelling long-lived intracellular molecules with fluorescent dye.

Uses

5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN is a Non-fluorescent cell permeant amine-reactive probe for long term tracing of cell.

General Description

5-(and-6)-Carboxyfluorescein diacetate N-succinimidyl ester (CFSE) is a fluorescent dye, which is membrane permeable. It labels cells by covalently binding to intracellular molecules. CFSE is used to track lymphocyte migration and proliferation.

Biochem/physiol Actions

5(6)-Carboxyfluorescein diacetate N-succinimidyl ester is used as an indicator for esterase activity.

5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN Suppliers

Canada 1 China 133 Europe 2 Germany 1 Japan 1 South Korea 1 Switzerland 3 United Kingdom 3 United States 17 Global 162
Dojindo Molecular Technologies, Inc.
Tel
--
Fax
--
Email
sasamoto@dojindo.co.jp
Country
Japan
ProdList
322
Advantage
75
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View Lastest Price from 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN manufacturers

Career Henan Chemical Co
Product
5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN 150347-59-4
Price
US $3.00/KG
Min. Order
1KG
Purity
90%
Supply Ability
100KG
Release date
2020-01-29

150347-59-4, 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEINRelated Search:

6-Carboxyfluorescein 5-CFDA N-succinimidyl ester 6-Carboxyfluorescein 3’,6’-Diacetate N-Succinimidyl Ester BIS-(4-METHOXYPHENYL) ETHER 4-(2 5-DIMETHOXYPHENYL)BUTYRIC ACID 97 TERT-BUTYL 3-BUTENOATE 3,5-BIS(CHLOROMETHYL)PYRIDINE HCL 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN GAMMA-PHENYL-GAMMA-BUTYROLACTONE 4,4'-Oxydiphenol 6-CARBOXYFLUORESCEIN DIACETATE 5(6)-Carboxyfluorescein Fluorescein diacetate 5(6)-CFDA 5-CARBOXYFLUORESCEIN DIACETATE 4-(3-ACETOXYPHENYL)-1-BUTENE 4-(2,5-DIMETHOXYPHENYL)-1-BUTENE ACRYLOYL-X, SE Nhs Ester

  • CARBOXYFLUORESCEIN DIACETATE, NHS ESTER
  • CFSE
  • 5(6)-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXY-SUCCINIMIDE ESTER
  • 5(6)-CARBOXYFLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER
  • 5-CARBOXYFLUORESCEIN-NHS DIACETATE
  • 5-CARBOXY-DI-O-ACETYLFLUORESCEIN N-SUCCINIMIDYL ESTER
  • 5-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXYSUCCINIMIDE ESTER
  • 5-CARBOXY-FLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER
  • 5-FAM-NHS DIACETATE
  • 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN
  • ≥90% (HPCE)
  • 5(6)-carboxyfluorescein diacetate N-succinimidyl este
  • -Cellstain-Cfse
  • 5-or6-(N-Succiimidyloxycarbonyl)-3',6'-O,O'-diacethylfluorescein
  • 5-or6-(N-Succinimidyloxycarbonyl)-fluorescein3',6'-diacetate
  • 3'',6''-O,O''-Diacetyl-5(6)-(N-succinimidyloxycarbonyl)-fluorescein
  • 5(6)-FAM DA SE
  • 1-[[[3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-
  • 3',6'-Bis(acetyloxy)-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic Acid 2,5-Dioxo-1-pyrrolidinyl Ester
  • 5(6)-Carboxyfluorescein 3',6'-Diacetate N-SucciniMidyl Ester
  • 5(6)-CFDA, SE [5(6)-Carboxyfluorescein diacetate, succiniMidyl ester]
  • 5(6)-Carboxyfluorescein diacetate, succinimidyl ester(CFDA)
  • Carboxyfluorescein diacetate, succinimidyl ester
  • CFDA SE
  • NHS ester
  • 5(6)-CFDA (SE [5(6)-Carboxyfluorescein diacetate
  • Spiro[isobenzofuran-1(3h),9′-[9h]xanthene], 2,5-pyrrolidinedione derivative
  • 5-(6)-carboxy' Uorescein Diacetate Succinimidyl Ester
  • CFSE [5-(and 6)-Carboxyfluorescein diacetate, succinimidyl ester] *CAS 150347-59-4*
  • ReadiUse CFSE [5-(and 6)-Carboxyfluorescein diacetate, succinimidyl ester] *CAS 150347-59-4*
  • 2,5-Dioxopyrrolidin-1-ylacetatecompoundwith3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyldiacetate(1:1)
  • Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylicacid, 3',6'-bis(acetyloxy)-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
  • Cell proliferation tracer fluorescence probe
  • 5-or 6-(N-Succinimidyloxycarbonyl)-3', 6'-O,O'-diacetylfluorescein (CFSE)
  • 5(6)-CFDA N-succinmidyl ester
  • Carboxyfluorescein succinimidyl ester
  • CFSE (CFDA-SE)
  • CFSE[5-(and 6)-Carboxyfluorescein diacetate
  • 5(6)-CFDA N-succinimidyl ester (CFSE)
  • 5(6)-CFDA N-succinmidyl este
  • 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN
  • Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
  • Cell Proliferation Tracer Fluorescent Probe (CFDASE)
  • 150347-59-4
  • C58H38N2O22
  • Fluorescent Probes, Labels, Particles and Stains
  • Detection
  • Biochemicals and Reagents
  • BioChemical
  • marker
  • Fluorescent
  • Xanthene
  • Aromatics
  • Fluorescent Labels & Indicators
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals