DEPMPO

ChemicalBook > CAS DataBase List > DEPMPO

Product Name: DEPMPO
CAS No.: 157230-67-6
Chemical Name: DEPMPO
Synonyms: DEPMPO;5-(Diethoxyphosphoryl)-;5-(DIETHYLPHOSPHONO)-5-METHYL-1-PYRROLINE N-OXIDE;5-(DIETHOXYPHOSPHORYL)-5-METHYL-1-PYRROLINE-N-OXIDE;5-(DIETHOXYPHOSPHONYL)-5-METHYL-1-PYRROLINE-N-OXIDE;5-(Diethylphosphono)-5-methyl-1-pyrrolineN-Oxide>5-(Diethylphosphono)-5-methyl-1-pyrroline N-Oxide;2-DIETHYLPHOSPHONO-2-METHYL-3,4-DIHYDRO-2H-PYRROLE 1-OXIDE;(2-METHYL-3,4-DIHYDRO-1-OXIDE-2H-PYRROL-2-YL)DIETHYLPHOSPHONATE;(3,4-Dihydro-2-methyl-1-oxido-2H-pyrrol-2-yl)-phosphonic acid diethyl ester
CBNumber: CB3675728
Molecular Formula: C9H18NO4P
Formula Weight: 235.22
MOL File: 157230-67-6.mol

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DEPMPO Property

Boiling point:: 412.4±34.0 °C(Predicted)
Density: 1.14±0.1 g/cm3(Predicted)
storage temp.: Freezer
solubility: Soluble in Water or Ethanol.
form: Colorless to light yellow oil.
pka: 1.74±0.40(Predicted)
color: Pale yellow
Stability:: Hygroscopic Oil, Light Sensitive

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10006435
Product name: DEPMPO
Purity: ≥98%
Packaging: 50mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 10006435
Product name: DEPMPO
Purity: ≥98%
Packaging: 250mg
Price: $513
Updated: 2024/03/01

Cayman Chemical

Product number: 10006435
Product name: DEPMPO
Purity: ≥98%
Packaging: 500mg
Price: $961
Updated: 2024/03/01

TRC

Product number: D442000
Product name: 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide
Packaging: 100mg
Price: $265
Updated: 2021/12/16

TRC

Product number: D442000
Product name: 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide
Packaging: 5mg
Price: $95
Updated: 2021/12/16

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DEPMPO Chemical Properties,Usage,Production

Description

DEPMPO (157230-67-6) is a spin trap capable of detecting oxygen, nitrogen, sulfur and carbon-centered free radicals both in vitro and in vivo. DEPMPO is useful for distinguishing between superoxide-dependent pathways of hydroxyl radical generation, and those that are superoxide independent.

Chemical Properties

DEPMPO is Pale Yellow Oil

Uses

DEPMPO is a spin trap useful as a probe for free radical formation during myocardial ischemia/reperfusion injury. An analogue of DMPO

Uses

DEPMPO is the most efficient spin trap for the in vitro detection of O-, N-, S- and C-centered free radicals both invitro and invivo. It has a longer life-time than DMPO and can distinguish between superoxide-dependent and independent mechanisms that lead to the hydroxyl radical. It is less lipophilic (Kp=0.16) than DIPPMPO.

References

1) Liu et al. (1999), Evaluation of DEPMPO as a spin trapping agent in biological systems; Free Radic. Biol. Med., 26 714 2) Shi et al. (2005), Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species; Arch. Biochem. Biophys., 437 59 3) Culcasi et al. (2012), EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: evidence for NADPH oxidase and mitochondrial stimulation; Chem. Biol. Interact., 199 161 4) Tampieri et al. (2019), Comment on “Water Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos; ACS Sens. E-pub. Ahead of Print [Focus Citation]

DEPMPO Preparation Products And Raw materials

Raw materials

Preparation Products

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157230-67-6, DEPMPORelated Search:

1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide Ambroxol Idebenone Celastrol 1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine (1-AMINOPROPYL)PHOSPHONIC ACID (1-AMINOBUTYL)PHOSPHONIC ACID (1-AMINO-1-METHYLPROPYL)PHOSPHONIC ACID HYDRATE 5-(DIISOPROPOXYPHOSPHORYL)-5-METHYL-1-PYRROLINE-N-OXIDE (1-AMINO-1-METHYLBUTYL)PHOSPHONIC ACID HYDRATE (1-AMINO-1-METHYLETHYL)PHOSPHONIC ACID 2-(DIETHOXYPHOSPHORYL)-2-PHENETHYL-3,4-DIHYDRO-2H-PYRROLE 1-OXIDE (1-AMINO-1-METHYLPROPYL)PHOSPHONIC ACID DEPMPO

DEPMPO

(2-METHYL-3,4-DIHYDRO-1-OXIDE-2H-PYRROL-2-YL)DIETHYLPHOSPHONATE

2-DIETHYLPHOSPHONO-2-METHYL-3,4-DIHYDRO-2H-PYRROLE 1-OXIDE

5-(DIETHYLPHOSPHONO)-5-METHYL-1-PYRROLINE N-OXIDE

5-(DIETHOXYPHOSPHONYL)-5-METHYL-1-PYRROLINE-N-OXIDE

5-(DIETHOXYPHOSPHORYL)-5-METHYL-1-PYRROLINE-N-OXIDE

5-(Diethoxyphosphoryl)-

P-(3,4-Dihydro-2-Methyl-1-oxido-2H-pyrrol-2-yl)phosphonic Acid Diethyl Ester

(3,4-Dihydro-2-methyl-1-oxido-2H-pyrrol-2-yl)-phosphonic acid diethyl ester

5-(Diethylphosphono)-5-methyl-1-pyrroline <i>N</i>-Oxide

5-(Diethylphosphono)-5-methyl-1-pyrrolineN-Oxide&gt

Phosphonic acid, P-(3,4-dihydro-2-methyl-1-oxido-2H-pyrrol-2-yl)-, diethyl ester

157230-67-6

C9H18NO4P

Spin Trapping Reagents

ESR Spectrometry

Spin Labeling Compounds

Analytical Chemistry

ESR Spectrometry

Spin Trapping Reagents