Pyraclofos
- Product Name
- Pyraclofos
- CAS No.
- 77458-01-6
- Chemical Name
- Pyraclofos
- Synonyms
- TIA 230;SC 1069;OMS3034;VOLTAGE;BOLTAGE;VOLTAGE(R);BOLTAGE(R);STARLEX(R);PYRACLOFOS;Pyraclofos Standard
- CBNumber
- CB3681581
- Molecular Formula
- C14H18ClN2O3PS
- Formula Weight
- 360.8
- MOL File
- 77458-01-6.mol
Pyraclofos Property
- Melting point:
- 25°C
- Boiling point:
- 164approximate 164℃(0.013hPa)
- Density
- 1.27
- vapor pressure
- 1.6×10-6 Pa (20 °C)
- storage temp.
- 0-6°C
- Water Solubility
- 33
- form
- liquid
- Specific Gravity
- 1.271 (28℃)
- CAS DataBase Reference
- 77458-01-6(CAS DataBase Reference)
- EPA Substance Registry System
- Phosphorothioic acid, O-[1-(4-chlorophenyl)-1H-pyrazol- 4-yl] O-ethyl S-propyl ester(77458-01-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- HCH0142242
- Product name
- OXO-[1-(4-CHLOROPHENYL)-1H-PYRAZOL-4-YL] OXO-ETHYL S-PROPYL PHOSPHOROTHIOATE
- Purity
- 98.00%
- Packaging
- 0.25G
- Price
- $935
- Updated
- 2021/12/16
- Product number
- MT-57377
- Product name
- O-[1-(4-Chlorophenyl)-1H-pyrazol-4-yl]O-ethylS-propylphosphorothioate
- Purity
- 98%
- Packaging
- 0.25g
- Price
- $280
- Updated
- 2021/12/16
Pyraclofos Chemical Properties,Usage,Production
Uses
Pyraclofos is used to control Lepidoptera, Coleoptera, mites and nematodes in fruit, vegetables, ornamentals and forestry. It has also been used in a human health application to control filarial worms.
Definition
ChEBI: Pyraclofos is an organic thiophosphate, an organothiophosphate insecticide, an organochlorine insecticide, a member of pyrazoles, a member of monochlorobenzenes and an organosulfur compound. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an agrochemical.
Metabolic pathway
Pyraclofos is apparently subjected in insects to a metabolic activation to yield a more active acetylcholinesterase inhibitor which is possibly a thiooxidized metabolite. The compound is very rapidly degraded in mammals to inactive metabolites via P-O-aryl, P-O-alkyl and P-S-alkyl cleavage which explains its favourable selective toxicity. In both mammals and plants the principal degradative route is via P-O-aryl cleavage to give 1-(4-chlorophenyl)-4-hydroxypyrazolwe hich is rapidly conjugated.
Metabolism
Pyraclofos is metabolized to an active AChE inhibitor, probably by the oxidation of the sulfur atom in the phosphorothiolate linkage. The half-life in soil is 3–38 d, depending on soil type.
Toxicity evaluation
The acute oral LD50 for rats is 237 mg/kg. The inhalation LC50 for rats is 1.69 mg/L air. NOEL (2 yr) for rats is 0.10–0.12 mg/kg diet (0.005–0.006 mg/kg/d). Pyraclofos administered to rats is rapidly degraded, and more than 90% of the dose is excreted principally in the urine within 24 h. The degradation routes are cleavages of the P?S, P?O-alkyl, and P?O-aryl bonds in both animals and plants.
Degradation
The DT50 for hydrolysis in water at pH 7 (25 °C) was 29 days (PM).
Pyraclofos Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pyraclofos manufacturers
- Product
- Pyraclofos 77458-01-6
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 100kg
- Release date
- 2020-01-07