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Pyraclofos

Product Name
Pyraclofos
CAS No.
77458-01-6
Chemical Name
Pyraclofos
Synonyms
TIA 230;SC 1069;OMS3034;VOLTAGE;BOLTAGE;VOLTAGE(R);BOLTAGE(R);STARLEX(R);PYRACLOFOS;Pyraclofos Standard
CBNumber
CB3681581
Molecular Formula
C14H18ClN2O3PS
Formula Weight
360.8
MOL File
77458-01-6.mol
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Pyraclofos Property

Melting point:
25°C
Boiling point:
164approximate 164℃(0.013hPa)
Density 
1.27
vapor pressure 
1.6×10-6 Pa (20 °C)
storage temp. 
0-6°C
Water Solubility 
33
form 
liquid
Specific Gravity
1.271 (28℃)
CAS DataBase Reference
77458-01-6(CAS DataBase Reference)
EPA Substance Registry System
Phosphorothioic acid, O-[1-(4-chlorophenyl)-1H-pyrazol- 4-yl] O-ethyl S-propyl ester(77458-01-6)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
RIDADR 
3018
RTECS 
TE8346000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0142242
Product name
OXO-[1-(4-CHLOROPHENYL)-1H-PYRAZOL-4-YL] OXO-ETHYL S-PROPYL PHOSPHOROTHIOATE
Purity
98.00%
Packaging
0.25G
Price
$935
Updated
2021/12/16
AHH
Product number
MT-57377
Product name
O-[1-(4-Chlorophenyl)-1H-pyrazol-4-yl]O-ethylS-propylphosphorothioate
Purity
98%
Packaging
0.25g
Price
$280
Updated
2021/12/16
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Pyraclofos Chemical Properties,Usage,Production

Uses

Pyraclofos is used to control Lepidoptera, Coleoptera, mites and nematodes in fruit, vegetables, ornamentals and forestry. It has also been used in a human health application to control filarial worms.

Definition

ChEBI: Pyraclofos is an organic thiophosphate, an organothiophosphate insecticide, an organochlorine insecticide, a member of pyrazoles, a member of monochlorobenzenes and an organosulfur compound. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an agrochemical.

Metabolic pathway

Pyraclofos is apparently subjected in insects to a metabolic activation to yield a more active acetylcholinesterase inhibitor which is possibly a thiooxidized metabolite. The compound is very rapidly degraded in mammals to inactive metabolites via P-O-aryl, P-O-alkyl and P-S-alkyl cleavage which explains its favourable selective toxicity. In both mammals and plants the principal degradative route is via P-O-aryl cleavage to give 1-(4-chlorophenyl)-4-hydroxypyrazolwe hich is rapidly conjugated.

Metabolism

Pyraclofos is metabolized to an active AChE inhibitor, probably by the oxidation of the sulfur atom in the phosphorothiolate linkage. The half-life in soil is 3–38 d, depending on soil type.

Toxicity evaluation

The acute oral LD50 for rats is 237 mg/kg. The inhalation LC50 for rats is 1.69 mg/L air. NOEL (2 yr) for rats is 0.10–0.12 mg/kg diet (0.005–0.006 mg/kg/d). Pyraclofos administered to rats is rapidly degraded, and more than 90% of the dose is excreted principally in the urine within 24 h. The degradation routes are cleavages of the P?S, P?O-alkyl, and P?O-aryl bonds in both animals and plants.

Degradation

The DT50 for hydrolysis in water at pH 7 (25 °C) was 29 days (PM).

Pyraclofos Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyraclofos Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
TianJin Alta Scientific Co., Ltd.
Tel
022-65378550-8551
Fax
+86-022-2532-9655
Email
contact@altascientific.com
Country
China
ProdList
2773
Advantage
58
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
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View Lastest Price from Pyraclofos manufacturers

Career Henan Chemical Co
Product
Pyraclofos 77458-01-6
Price
US $2.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100kg
Release date
2020-01-07

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