ChemicalBook > CAS DataBase List > Pyraclofos

Pyraclofos

Product Name
Pyraclofos
CAS No.
77458-01-6
Chemical Name
Pyraclofos
Synonyms
TIA 230;SC 1069;OMS3034;VOLTAGE;BOLTAGE;VOLTAGE(R);BOLTAGE(R);STARLEX(R);PYRACLOFOS;Pyraclofos Standard
CBNumber
CB3681581
Molecular Formula
C14H18ClN2O3PS
Formula Weight
360.8
MOL File
77458-01-6.mol
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Pyraclofos Property

Melting point:
25°C
Boiling point:
164approximate 164℃(0.013hPa)
Density 
1.27
vapor pressure 
1.6×10-6 Pa (20 °C)
storage temp. 
0-6°C
form 
liquid
Water Solubility 
33
Specific Gravity
1.271 (28℃)
CAS DataBase Reference
77458-01-6(CAS DataBase Reference)
EPA Substance Registry System
Phosphorothioic acid, O-[1-(4-chlorophenyl)-1H-pyrazol- 4-yl] O-ethyl S-propyl ester(77458-01-6)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
RIDADR 
3018
RTECS 
TE8346000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

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Pyraclofos Chemical Properties,Usage,Production

Uses

Pyraclofos is used to control Lepidoptera, Coleoptera, mites and nematodes in fruit, vegetables, ornamentals and forestry. It has also been used in a human health application to control filarial worms.

Metabolic pathway

Pyraclofos is apparently subjected in insects to a metabolic activation to yield a more active acetylcholinesterase inhibitor which is possibly a thiooxidized metabolite. The compound is very rapidly degraded in mammals to inactive metabolites via P-O-aryl, P-O-alkyl and P-S-alkyl cleavage which explains its favourable selective toxicity. In both mammals and plants the principal degradative route is via P-O-aryl cleavage to give 1-(4-chlorophenyl)-4-hydroxypyrazolwe hich is rapidly conjugated.

Metabolism

Pyraclofos is metabolized to an active AChE inhibitor, probably by the oxidation of the sulfur atom in the phosphorothiolate linkage. The half-life in soil is 3–38 d, depending on soil type.

Toxicity evaluation

The acute oral LD50 for rats is 237 mg/kg. The inhalation LC50 for rats is 1.69 mg/L air. NOEL (2 yr) for rats is 0.10–0.12 mg/kg diet (0.005–0.006 mg/kg/d). Pyraclofos administered to rats is rapidly degraded, and more than 90% of the dose is excreted principally in the urine within 24 h. The degradation routes are cleavages of the P?S, P?O-alkyl, and P?O-aryl bonds in both animals and plants.

Degradation

The DT50 for hydrolysis in water at pH 7 (25 °C) was 29 days (PM).

Pyraclofos Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyraclofos Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
future industrial shanghai co., ltd
Tel
400-0066-400;021-60496031
Fax
021-55660885
Email
sales@jonln.com;sales@jonln.com
Country
China
ProdList
1999
Advantage
65
BEST-REAGENT
Tel
400-1166-196;028-84555506- ;028-84555506-
Email
cdhxsj@163.com;1955352637@qq.com;cdhxsj@163.com
Country
China
ProdList
11718
Advantage
57
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810- ;025-57798810-
Fax
025-57019371
Email
sales@sunlidabio.com;sales@sunlidabio.com
Country
China
ProdList
3756
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400;021-60496031
Fax
021-55660885
Email
422131432@qq.com;422131432@qq.com
Country
China
ProdList
9998
Advantage
55
TianJin Alta Scientific Co., Ltd.
Tel
+86-022-6537-8550
Fax
+86-022-2532-9655
Email
contact@altascientific.com
Country
China
ProdList
2775
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432-
Fax
0571-87396431
Email
sales@jhechem.com;
Country
China
ProdList
13965
Advantage
53
Alta Scientific Co., Ltd.
Tel
022-65378550- ;022-65378550-
Fax
022-2532-9655
Email
sales@altascientific.com;marketing@altascientific.com
Country
China
ProdList
9070
Advantage
55
Codow Chemical Co.,Ltd.
Tel
020-38056109-1040
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
18941
Advantage
55
West Asia Chemical Technology (Shandong) Co. Ltd
Fax
0539-6365991
Email
3007715519@qq.com;3007715519@qq.com
Country
China
ProdList
27467
Advantage
60
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View Lastest Price from Pyraclofos manufacturers

Career Henan Chemical Co
Product
Pyraclofos 77458-01-6
Price
US $2.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100kg
Release date
2020-01-07

77458-01-6, PyraclofosRelated Search:


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