THIOPHOSPHORYL CHLORIDE Property

Melting point:

-35 °C (lit.)

Boiling point:

125 °C (lit.)

Density 

1.668 g/mL at 25 °C (lit.)

vapor pressure 

21.9hPa at 25℃

refractive index 

n20/D 1.555(lit.)

solubility 

benzene: soluble(lit.)

form 

liquid

color 

colorless

Specific Gravity

1.668

Water Solubility 

hydrolyzes in H2O, forming H3PO4, HCl, H2S; hydrolyzes rapidly in alkaline solutions; soluble benzene, CCl4, CS2, chloroform [MER06]

Sensitive 

moisture sensitive

Merck 

14,7356

Dielectric constant

2.5（25℃）

Stability:

Moisture Sensitive

CAS DataBase Reference

3982-91-0(CAS DataBase Reference)

EPA Substance Registry System

Phosphorothioic trichloride (3982-91-0)

Safety

Hazard Codes 

T+

Risk Statements 

22-26-34-52/53

Safety Statements 

26-28-36/37/39-45-61

RIDADR 

UN 1837 8/PG 2

WGK Germany 

2

RTECS 

XN2930000

F 

21

HazardClass 

8

PackingGroup 

II

HS Code 

28273985

Hazardous Substances Data

3982-91-0(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H330Fatal if inhaled

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

THIOPHOSPHORYL CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

clear colourless to slightly yellowish liquid

Uses

Thiophosphoryl chloride was used in the synthesis of O-ethyl dichlorothiophosphate.

General Description

A colorless fuming liquid. Boiling point 257°F (125 °C). Irritates the eyes and mucous membranes. Corrosive to metals and tissue.

Air & Water Reactions

Fumes in air. Decomposes in water to form phosphoric acid and hydrochloric acid (hydrogen chloride). Both substances are corrosive to metal or tissue. Can also form hydrogen sulfide (H2S), a toxic flammable gas, in reaction with water [AAR 1991].

Reactivity Profile

THIOPHOSPHORYL CHLORIDE is acidic. Incompatible with bases (including amines), with strong oxidizing agents, and with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Hazard

Strong irritant to skin and tissue.

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars etc.). Substance will react with water (some violently), releasing corrosive and/or toxic gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Safety Profile

Poison by inhalation. Moderately toxic by ingestion. A corrosive irritant to skin, eyes, and mucous membranes. Explosive reaction with methylmagnesium iodlde. Explosive reaction with pentaerythritol + heat. Reacts with water or steam to produce toxic and corrosive fumes. When heated to decomposition it emits highly toxic fumes of POx, SOx, and Cl-.

Purification Methods

Possible impurities are PCl5, H3PO4, HCl and AlCl3. Gently mix it with H2O to avoid a heavy emulsion; the product decoulorises immediately and settles to the bottom layer. It is soluble in *C6H6 and CCl4. [Duval Inorg Synth IV 73 1953.] HARMFUL VAPOURS.