Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

Product Name: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
CAS No.: 887267-53-0
Chemical Name: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Synonyms: Ethyl 3-(2,5-difluorophenyl);ETHYL 2,5-DIFLUOROBENZOYLACETATE;Ethyl 2,5-difluoro-β-oxobenzenepropanoate;ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE;Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+%;Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester;3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester;2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester
CBNumber: CB3689431
Molecular Formula: C11H10F2O3
Formula Weight: 228.19
MOL File: 887267-53-0.mol

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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Property

Boiling point:: 275.7±25.0 °C(Predicted)
Density: 1.251±0.06 g/cm3(Predicted)
pka: 10.28±0.50(Predicted)

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: E916705
Product name: Ethyl3-(2,5-Difluorophenyl)-3-oxopropanoate
Packaging: 500mg
Price: $285
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2629-3-30
Product name: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Purity: 97%
Packaging: 250mg
Price: $291
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2629-3-30
Product name: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Purity: 97%
Packaging: 1g
Price: $795
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0007231
Product name: ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE
Purity: 95.00%
Packaging: 5G
Price: $909.56
Updated: 2021/12/16

AK Scientific

Product number: 4567AC
Product name: Ethyl3-(2,5-difluorophenyl)-3-oxopropanoate
Packaging: 5g
Price: $1063
Updated: 2021/12/16

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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Chemical Properties,Usage,Production

Uses

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate is commonly utilized in organic synthesis as C-nucleophiles. One specific example is its reaction with the N-terminal electrophile CF3CHN2, resulting in the formation of CF3-heterocycles, namely ethyl 6-fluoro-4-oxo-1-(2,2,2-trifluoroethyl)-1,4-dihydrocinnoline-3-carboxylate[1].

References

[1] Arkhipov A, et al. Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2): Electrophilicity of the Terminal N?Atom. Organic Letters, 2016; 18: 3406–3409.

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Suppliers

China 44 India 1 Ukraine 1 United Kingdom 2 United States 9 Global 57

Aladdin Scientific

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887267-53-0, Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoateRelated Search:

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ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE

ETHYL 2,5-DIFLUOROBENZOYLACETATE

3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester

Ethyl 3-(2,5-difluorophenyl)

2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+%

Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester

Ethyl 2,5-difluoro-β-oxobenzenepropanoate

887267-53-0