ChemicalBook > CAS DataBase List > Glycylglycine

Glycylglycine

Product Name
Glycylglycine
CAS No.
556-50-3
Chemical Name
Glycylglycine
Synonyms
GLY-GLY;H-GLY-GLY-OH;DIGLYCINE;GLY-GLY-OH;N-GLYCYLGLYCINE;2-(2-aMinoacetaMido)acetic acid;2-[(2-Aminoacetyl)amino]acetic acid;Gly2;y-GL;Gly-Gl
CBNumber
CB3704259
Molecular Formula
C4H8N2O3
Formula Weight
132.12
MOL File
556-50-3.mol
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Glycylglycine Property

Melting point:
220-240 °C (dec.)
Boiling point:
267.18°C (rough estimate)
Density 
1.5851 (rough estimate)
vapor pressure 
0.058Pa at 20-50℃
refractive index 
1.4880 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: 1 M at 20 °C, clear, colorless
pka
3.139(at 25℃)
form 
Solid
color 
White
PH
4.5-6.0 (20℃, 1M in H2O)
PH Range
7.5 - 8.9
biological source
synthetic
Water Solubility 
SOLUBLE IN HOT WATER
λmax
λ: 260 nm Amax: 0.075
λ: 280 nm Amax: 0.072
Merck 
14,4503
BRN 
1765223
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
YMAWOPBAYDPSLA-UHFFFAOYSA-N
LogP
-0.92 at 25℃ and pH6
CAS DataBase Reference
556-50-3(CAS DataBase Reference)
NIST Chemistry Reference
N-Glycylglycine(556-50-3)
EPA Substance Registry System
Glycylglycine (556-50-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
24/25-26
WGK Germany 
3
10
TSCA 
Yes
HS Code 
29241900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2733
Product name
Diglycine (glycylglycine)
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
200 mg
Price
$173.85
Updated
2025/07/31
Sigma-Aldrich
Product number
50199
Product name
Gly-Gly
Purity
BioUltra, ≥99.5% (NT)
Packaging
10g
Price
$85.7
Updated
2025/07/31
Sigma-Aldrich
Product number
50199
Product name
Gly-Gly
Purity
BioUltra, ≥99.5% (NT)
Packaging
50g
Price
$325
Updated
2025/07/31
TCI Chemical
Product number
G0124
Product name
Glycylglycine
Purity
>99.0%(T)
Packaging
25g
Price
$41
Updated
2025/07/31
TCI Chemical
Product number
G0124
Product name
Glycylglycine
Purity
>99.0%(T)
Packaging
100g
Price
$124
Updated
2025/07/31
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Glycylglycine Chemical Properties,Usage,Production

Chemical Properties

White crystals

Uses

Glycylglycine is as a buffering reagent and also used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptides. It is also employed as a practical buffer with a buffering range of 7.5 - 8.9 (at 25°C). Valuable agent for experiments investigating peptide transport and absorption.

Definition

ChEBI: A dipeptide formed from glycine residues.

Synthesis Reference(s)

Journal of the American Chemical Society, 75, p. 5323, 1953 DOI: 10.1021/ja01117a053

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid. Diglycine is known to catalyze the formation of homo- and hetero dipeptides more efficiently than glycine.

Purification Methods

Crystallise glycylglycine from aqueous 50% EtOH or water at 50-60o by addition of EtOH. Dry it at 110o. It sublimes at 190-200o/0.3mm with 30% recovery [Gross & Gradsky J Am Chem Soc 77 1678 1955, King J Am Chem Soc 79 6153 1957]. [Beilstein 4 IV 2459.]

Glycylglycine Preparation Products And Raw materials

Raw materials

Preparation Products

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Glycylglycine Suppliers

Chengdu Baishixing Science and Technology Industry Co.,Ltd
Tel
13668201230
Fax
028-88530181
Email
yuanjun@cd-bsx.com
Country
China
ProdList
94
Advantage
55
Sichuan Tongsheng Amino acids Co.,Ltd.
Tel
0838-2274206 13908101207
Fax
+86-838-2274207
Email
sales@biots.cn
Country
China
ProdList
256
Advantage
66
Aobolihui
Tel
0917-18691729 18691729963
Email
2553382659@qq.com
Country
China
ProdList
4739
Advantage
58
Shanghai Yikefan Biotechnology Co., LTD
Tel
18221419461; 18221419461
Email
sales@yikefan.com
Country
China
ProdList
612
Advantage
58
Gansu Province Baishixing Pharmaceutical Co.,Ltd
Tel
13668201230
Email
1437493064@qq.com
Country
China
ProdList
59
Advantage
58
SHANGHAI YUANJU BIO-TECH CO., LTD
Tel
62750277 15618798178
Email
362310313@qq.com
Country
China
ProdList
469
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 13451648594
Email
mkt@yacoo.com.cn
Country
China
ProdList
4574
Advantage
58
Guangdong Ymarl Biotechnology Co., Ltd.
Tel
13482530519
Email
zhn2812@163.com
Country
China
ProdList
135
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
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View Lastest Price from Glycylglycine manufacturers

Chengdu Shengnuo Biopharm Co.,Ltd
Product
Dipeptide-15 556-50-3
Price
US $500.00-500.00/kg
Min. Order
1kg
Purity
≥99.00%
Supply Ability
1000000
Release date
2025-10-10
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Glycylglycine 556-50-3
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000kg/month
Release date
2021-07-06
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Glycylglycine 556-50-3
Price
US $999.00-800.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-22

556-50-3, GlycylglycineRelated Search:


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