Glycylglycine

Product Name: Glycylglycine
CAS No.: 556-50-3
Chemical Name: Glycylglycine
Synonyms: GLY-GLY;H-GLY-GLY-OH;DIGLYCINE;GLY-GLY-OH;N-GLYCYLGLYCINE;2-(2-aMinoacetaMido)acetic acid;2-[(2-Aminoacetyl)amino]acetic acid;Gly2;y-GL;Gly-Gl
CBNumber: CB3704259
Molecular Formula: C4H8N2O3
Formula Weight: 132.12
MOL File: 556-50-3.mol

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Glycylglycine Property

Melting point:: 220-240 °C (dec.)
Boiling point:: 267.18°C (rough estimate)
Density: 1.5851 (rough estimate)
vapor pressure: 0.058Pa at 20-50℃
refractive index: 1.4880 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: H₂O: 1 M at 20 °C, clear, colorless
pka: 3.139(at 25℃)
form: Solid
color: White
PH: 4.5-6.0 (20℃, 1M in H2O)
PH Range: 7.5 - 8.9
biological source: synthetic
Water Solubility: SOLUBLE IN HOT WATER
λmax: λ: 260 nm Amax: 0.075
λ: 280 nm Amax: 0.072
Merck: 14,4503
BRN: 1765223
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: YMAWOPBAYDPSLA-UHFFFAOYSA-N
LogP: -0.92 at 25℃ and pH6
CAS DataBase Reference: 556-50-3(CAS DataBase Reference)
NIST Chemistry Reference: N-Glycylglycine(556-50-3)
EPA Substance Registry System: Glycylglycine (556-50-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 24/25-26
WGK Germany: 3
F: 10
TSCA: Yes
HS Code: 29241900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 50199
Product name: Gly-Gly
Purity: BioUltra, ≥99.5% (NT)
Packaging: 10g
Price: $80.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 50199
Product name: Gly-Gly
Purity: BioUltra, ≥99.5% (NT)
Packaging: 50g
Price: $303
Updated: 2024/03/01

TCI Chemical

Product number: G0124
Product name: Glycylglycine
Purity: >99.0%(T)
Packaging: 25g
Price: $41
Updated: 2024/03/01

TCI Chemical

Product number: G0124
Product name: Glycylglycine
Purity: >99.0%(T)
Packaging: 100g
Price: $124
Updated: 2024/03/01

Alfa Aesar

Product number: A10523
Product name: Glycylglycine, 99%
Packaging: 25g
Price: $53.1
Updated: 2024/03/01

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Glycylglycine Chemical Properties,Usage,Production

Chemical Properties

White crystals

Uses

Glycylglycine is as a buffering reagent and also used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptides. It is also employed as a practical buffer with a buffering range of 7.5 - 8.9 (at 25°C). Valuable agent for experiments investigating peptide transport and absorption.

Definition

ChEBI: A dipeptide formed from glycine residues.

Synthesis Reference(s)

Journal of the American Chemical Society, 75, p. 5323, 1953 DOI: 10.1021/ja01117a053

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid. Diglycine is known to catalyze the formation of homo- and hetero dipeptides more efficiently than glycine.

Purification Methods

Crystallise glycylglycine from aqueous 50% EtOH or water at 50-60o by addition of EtOH. Dry it at 110o. It sublimes at 190-200o/0.3mm with 30% recovery [Gross & Gradsky J Am Chem Soc 77 1678 1955, King J Am Chem Soc 79 6153 1957]. [Beilstein 4 IV 2459.]

Glycylglycine Preparation Products And Raw materials

Raw materials

Ethylenediamine

Preparation Products

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Glycylglycine Suppliers

Americas 1 Belgium 3 Canada 3 China 408 Europe 5 France 2 Germany 8 India 32 Japan 11 Poland 1 Slovakia 1 Switzerland 10 United Kingdom 17 United States 74 USA 1 Global 577

Melford Laboratories Ltd.

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CARBONE SCIENTIFIC CO.,LTD

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MOLEKULA Ltd.

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ETA SCIENTIFIC Co.,Ltd

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VWR International

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View Lastest Price from Glycylglycine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Gly-Gly-OH 556-50-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-01-17

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Glycylglycine 556-50-3
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-12-04

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: Glycylglycine 556-50-3
Price: US $999.00-800.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-22

556-50-3, GlycylglycineRelated Search:

N-(Carboxymethyl)-N-(phosphonomethyl)-glycine Glutathione Glycine 9,9-Bis(4-hydroxyphenyl)fluorene Benzyl salicylate Bisphenol TMC Salicylanilide GLYCYL-L-PHENYLALANINE Copper Peptide Benzyl glycinate p-toluenesulfonate Copper glycinate Glycine tert butyl ester hydrochloride Glycinamide hydrochloride Glycine ethyl ester hydrochloride GLYCYL-L-PROLINE H-GLY-D-GLN-OH Glycyl-L-valine GLYCYL-DL-PHENYLALANINE

(2-Amino-acetylamino)-aceticacid

[(Aminoacetyl)amino]acetic acid

DIGLYCINE

GLYCYLGLYCINE

GLY-GLY-OH

GLY-GLY

H-GLY-GLY-OH

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Gycylglycine

Diglycine, Glycyl-glycine

2-[(2-Aminoacetyl)amino]acetic acid

L-Gly-L-Gly-OH

N-(Aminoacetyl)glycine

Diglycine N-Glycylglycine

Glycine,glycyl-

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Glycinedipeptide

Glycylglycin

Glycyl-glycin

GLYCYLGLYCINE (STD OF FISHER)

2-[(2-ammonio-1-oxoethyl)amino]acetate

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Glycylglycine ,98.5%

Glycylgycine

Glycylglyine

2-(Aminoacetamido)aceticacid

n-glycyl-glycin

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Glycylglycine, 99+% 25GR

H-Gly-Gly-OH Diglycine

Gly-Gl

2-(2-aMinoacetaMido)acetic acid

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Glycylgcine

Double GSH

GLY-GLY, BIOPERFORMANCE CERTIFIED, C

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Diglycocoll

Gly2

Glycine dipeptide

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Glycylglycine Buffer salt