ChemicalBook > CAS DataBase List > Glycylglycine

Glycylglycine

Product Name
Glycylglycine
CAS No.
556-50-3
Chemical Name
Glycylglycine
Synonyms
GLY-GLY;H-GLY-GLY-OH;DIGLYCINE;GLY-GLY-OH;N-GLYCYLGLYCINE;2-(2-aMinoacetaMido)acetic acid;2-[(2-Aminoacetyl)amino]acetic acid;Gly2;y-GL;Gly-Gl
CBNumber
CB3704259
Molecular Formula
C4H8N2O3
Formula Weight
132.12
MOL File
556-50-3.mol
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Glycylglycine Property

Melting point:
220-240 °C (dec.)
Boiling point:
267.18°C (rough estimate)
Density 
1.5851 (rough estimate)
vapor pressure 
0.058Pa at 20-50℃
refractive index 
1.4880 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: 1 M at 20 °C, clear, colorless
pka
3.139(at 25℃)
form 
Solid
color 
White
PH
4.5-6.0 (20℃, 1M in H2O)
PH Range
7.5 - 8.9
Water Solubility 
SOLUBLE IN HOT WATER
λmax
λ: 260 nm Amax: 0.075
λ: 280 nm Amax: 0.072
Merck 
14,4503
BRN 
1765223
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
YMAWOPBAYDPSLA-UHFFFAOYSA-N
LogP
-0.92 at 25℃ and pH6
CAS DataBase Reference
556-50-3(CAS DataBase Reference)
NIST Chemistry Reference
N-Glycylglycine(556-50-3)
EPA Substance Registry System
Glycylglycine (556-50-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
24/25-26
WGK Germany 
3
F 
10
TSCA 
Yes
HS Code 
29241900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
50199
Product name
Gly-Gly
Purity
BioUltra, ≥99.5% (NT)
Packaging
10g
Price
$80.1
Updated
2024/03/01
Sigma-Aldrich
Product number
50199
Product name
Gly-Gly
Purity
BioUltra, ≥99.5% (NT)
Packaging
50g
Price
$303
Updated
2024/03/01
TCI Chemical
Product number
G0124
Product name
Glycylglycine
Purity
>99.0%(T)
Packaging
25g
Price
$41
Updated
2024/03/01
TCI Chemical
Product number
G0124
Product name
Glycylglycine
Purity
>99.0%(T)
Packaging
100g
Price
$124
Updated
2024/03/01
Alfa Aesar
Product number
A10523
Product name
Glycylglycine, 99%
Packaging
25g
Price
$53.1
Updated
2024/03/01
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Glycylglycine Chemical Properties,Usage,Production

Chemical Properties

White crystals

Uses

Glycylglycine is as a buffering reagent and also used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptides. It is also employed as a practical buffer with a buffering range of 7.5 - 8.9 (at 25°C). Valuable agent for experiments investigating peptide transport and absorption.

Definition

ChEBI: A dipeptide formed from glycine residues.

Synthesis Reference(s)

Journal of the American Chemical Society, 75, p. 5323, 1953 DOI: 10.1021/ja01117a053

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid. Diglycine is known to catalyze the formation of homo- and hetero dipeptides more efficiently than glycine.

Purification Methods

Crystallise glycylglycine from aqueous 50% EtOH or water at 50-60o by addition of EtOH. Dry it at 110o. It sublimes at 190-200o/0.3mm with 30% recovery [Gross & Gradsky J Am Chem Soc 77 1678 1955, King J Am Chem Soc 79 6153 1957]. [Beilstein 4 IV 2459.]

Glycylglycine Preparation Products And Raw materials

Raw materials

Ethylenediamine

Preparation Products

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View Lastest Price from Glycylglycine manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Glycylglycine 556-50-3
Price
US $999.00-800.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Glycylglycine 556-50-3
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000kg/month
Release date
2021-07-06
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Gly-Gly-OH 556-50-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-01-17

556-50-3, GlycylglycineRelated Search:

N-(Carboxymethyl)-N-(phosphonomethyl)-glycine Glutathione Glycine 9,9-Bis(4-hydroxyphenyl)fluorene Benzyl salicylate Bisphenol TMC Salicylanilide GLYCYL-L-PHENYLALANINE Copper Peptide Benzyl glycinate p-toluenesulfonate Copper glycinate Glycine tert butyl ester hydrochloride Glycinamide hydrochloride Glycine ethyl ester hydrochloride GLYCYL-L-PROLINE H-GLY-D-GLN-OH Glycyl-L-valine GLYCYL-DL-PHENYLALANINE

  • (2-Amino-acetylamino)-aceticacid
  • [(Aminoacetyl)amino]acetic acid
  • DIGLYCINE
  • GLYCYLGLYCINE
  • GLY-GLY-OH
  • GLY-GLY
  • H-GLY-GLY-OH
  • Glycylglycine, Free Base
  • gly-gly free base
  • GLY-GLY, BIOTECHNOLOGY PREFORMANCE CERTI FIED
  • GLY-GLY FREE BASE SIGMAULTRA
  • Glycylglycine (Chemalog Grade)
  • GlycylGlycineForBiochemistry
  • GlycylglycineA.R.
  • G-132Glycyl-Glycine
  • Gly-Gly(Glycylglycine)
  • Diglycime
  • GLYCYLGLYCINE,BIOLOGICALBUFFER
  • GLYCYLGLYCINE,ULTRAPURE
  • GLYCYLGLYCINE (GLY-GLY)
  • Glycyglycine
  • Glycylglycine,98%
  • Glycylglycine, 99+%
  • GLYCYL GLYCINE extrapure
  • Gycylglycine
  • Diglycine, Glycyl-glycine
  • 2-[(2-Aminoacetyl)amino]acetic acid
  • L-Gly-L-Gly-OH
  • N-(Aminoacetyl)glycine
  • Diglycine N-Glycylglycine
  • Glycine,glycyl-
  • Glycine,N-glycyl-
  • Glycinedipeptide
  • Glycylglycin
  • Glycyl-glycin
  • GLYCYLGLYCINE (STD OF FISHER)
  • 2-[(2-ammonio-1-oxoethyl)amino]acetate
  • N-GLYCYLGLYCINE
  • Glycylglycine ,98.5%
  • Glycylgycine
  • Glycylglyine
  • 2-(Aminoacetamido)aceticacid
  • n-glycyl-glycin
  • Glycylglycine, 99+% 100GR
  • Glycylglycine, 99+% 25GR
  • H-Gly-Gly-OH Diglycine
  • Gly-Gl
  • 2-(2-aMinoacetaMido)acetic acid
  • Gly-Gly Vetec(TM) reagent grade, 99%
  • Glycylgcine
  • Double GSH
  • GLY-GLY, BIOPERFORMANCE CERTIFIED, C
  • Gly-Gly≥ 99% (Titration)
  • Diglycocoll
  • Gly2
  • Glycine dipeptide
  • Glycine, N-glycyl-
  • Glycylglycine Buffer salt