ChemicalBook > CAS DataBase List > BOC-TRANS-4-AMINOCYCLOHEXANOL

BOC-TRANS-4-AMINOCYCLOHEXANOL

Product Name
BOC-TRANS-4-AMINOCYCLOHEXANOL
CAS No.
111300-06-2
Chemical Name
BOC-TRANS-4-AMINOCYCLOHEXANOL
Synonyms
104582;tert-butyl (1r;BOC-TRANS-4-AMINOCYCLOHEXANOL;TRANS-4-BOC-AMINOCYCLOHEXANOL;Trans-4-n-boc-aminocylohexanol;TRANS-4-N-BOC-AMINOCYCLOHEXANOL;TRANS-N-4-BOC-AMINOCYCLOHEXANOL;TRANS-N-BOC-4-AMINO-CYCLOHEXANOL;TRANS-4-BOC-AMINO-1-CYCLOHEXANOL;4r)-4-hydroxycyclohexylcarbaMate
CBNumber
CB3708479
Molecular Formula
C11H21NO3
Formula Weight
215.29
MOL File
111300-06-2.mol
More
Less

BOC-TRANS-4-AMINOCYCLOHEXANOL Property

Melting point:
172-173°C
Boiling point:
337.7±31.0 °C(Predicted)
Density 
1.06±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform. Ethyl Acetate
form 
powder to crystal
pka
12.36±0.40(Predicted)
color 
White to Almost white
InChIKey
DQARDWKWPIRJEH-KYZUINATSA-N
CAS DataBase Reference
111300-06-2(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
Hazard Note 
Irritant
HS Code 
2906190090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
B3564
Product name
trans-4-(tert-Butoxycarbonylamino)cyclohexanol
Purity
>98.0%(GC)(N)
Packaging
1g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
B3564
Product name
trans-4-(tert-Butoxycarbonylamino)cyclohexanol
Purity
>98.0%(GC)(N)
Packaging
5g
Price
$84
Updated
2025/07/31
TRC
Product number
B617685
Product name
trans-4-(Boc-amino)cyclohexanol
Packaging
25g
Price
$240
Updated
2021/12/16
TRC
Product number
B617685
Product name
trans-4-(Boc-amino)cyclohexanol
Packaging
100g
Price
$725
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0032478
Product name
TRANS-4-BOC-AMINOCYCLOHEXANOL
Purity
95.00%
Packaging
5G
Price
$942.85
Updated
2021/12/16
More
Less

BOC-TRANS-4-AMINOCYCLOHEXANOL Chemical Properties,Usage,Production

Uses

trans-4-(Boc-amino)cyclohexanol is an intermediate in the synthesis of potent activators of Heme-regulated inhibitor kinase.

Synthesis

24424-99-5

50910-54-8

111300-06-2

Step 1: trans-4-Aminocyclohexanol hydrochloride (5.0 g, 33 mmol) was dissolved in 1,4-dioxane (100 mL) and the resulting solution was cooled to 0 °C. Aqueous sodium hydroxide solution (40 mL, 1 N) was slowly added and the reaction mixture was stirred for 15 minutes. Subsequently, di-tert-butyl dicarbonate (7.9 g, 36 mmol) pre-dissolved in 1,4-dioxane (65 mL) was added. The reaction mixture was stirred at room temperature for 14 hours. Upon completion of the reaction, the reaction mixture was neutralized with 1 N hydrochloric acid and extracted with ethyl acetate. The organic phase was washed sequentially with 1 N hydrochloric acid, water and saturated saline, dried over anhydrous sodium sulfate, filtered and concentrated in vacuum to give the white solid product trans-4-BOC-aminocyclohexanol (7.0 g, 100% yield). Mass spectrometry analysis showed (M + H)+ = 216.15.

References

[1] Patent: US2005/54626, 2005, A1. Location in patent: Page/Page column 47
[2] Heterocycles, 2002, vol. 58, p. 471 - 504
[3] Patent: WO2007/67629, 2007, A1. Location in patent: Page/Page column 63

BOC-TRANS-4-AMINOCYCLOHEXANOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

BOC-TRANS-4-AMINOCYCLOHEXANOL Suppliers

Americas 1 Canada 1 China 152 Europe 1 Germany 2 India 7 Japan 1 United Kingdom 8 United States 30 Global 203
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd.
Tel
010-81520996 13439320863
Fax
010-81520996
Email
hengpugao@126.com
Country
China
ProdList
159
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Goodee Pharma Co., Ltd.
Tel
0512-62956210
Email
yongyan@goodeepharma.com
Country
China
ProdList
132
Advantage
60
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 18982182443
Email
yangli@happysyn.com
Country
China
ProdList
2151
Advantage
55
Beijing Yisiyan Technology Research Center
Tel
010-56645598 13366904824
Fax
01062230033
Email
bjkaida@163.com
Country
China
ProdList
1618
Advantage
59
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
15928766785 15928766785
Fax
QQ961458712
Email
wupengcheng@astatech.cn
Country
China
ProdList
1987
Advantage
55
Wuhan HengHeDa Pharm Co., Ltd.
Tel
027-84888681 18086046872
Fax
027-84888682
Email
hhdpharm@hotmail.com
Country
China
ProdList
105
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Shanghai Hekang Biotechnology Co., Ltd.
Tel
18939837085
Fax
2880152141(QQ)
Email
youchemicals@gmail.com
Country
China
ProdList
1839
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
2598
Advantage
60
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9979
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Hangzhou Milestone Pharmtech Co., Ltd.
Tel
0571-82896630 18969958410
Email
sales_hz@milestonepharmtech.com
Country
China
ProdList
4894
Advantage
55
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
SanoChem (Chengdu) Tech. Co., Ltd.
Tel
28-87999436 02887999436
Fax
QQ:2746983436
Email
sales@sano-chem.com
Country
China
ProdList
3795
Advantage
55
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
ShangHai Wisacheam Pharmaceutical Co., Ltd.
Tel
13817485796
Fax
QQ:895624079
Email
tim@wisacheampharm.com
Country
China
ProdList
3592
Advantage
58
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.
Tel
027-65388397 18164111589
Fax
027-65388397
Email
3321478047@qq.com
Country
China
ProdList
2007
Advantage
55
Nanjing River Chemical Co., Ltd.
Tel
13951936332 18305166317
Fax
-
Email
info@serpharm.com
Country
China
ProdList
493
Advantage
55
BTC Pharmaceutical CO. Ltd
Tel
15716293042 18862996710
Fax
0513-68015394
Email
15050603958@163.com
Country
China
ProdList
695
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
More
Less

View Lastest Price from BOC-TRANS-4-AMINOCYCLOHEXANOL manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
BOC-TRANS-4-AMINOCYCLOHEXANOL 111300-06-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
BOC-TRANS-4-AMINOCYCLOHEXANOL 111300-06-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kgs
Release date
2020-01-02

111300-06-2, BOC-TRANS-4-AMINOCYCLOHEXANOLRelated Search:

Carbamic acid, 3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester, tert-butyl 1H-pyrrol-2-ylcarbamate 2-(BOC-AMINO)-3-METHYLPYRIDINE tert-butyl (3-fluoropropyl)(2-hydroxyethyl)carbamate tert-butyl (3-formyl-4-hydroxyphenyl)carbamate TRANS-(4-HYDROXY-CYCLOHEXYLMETHYL)-CARBAMIC ACID TERT-BUTYL ESTER CarbaMic acid,[trans-4-[[[(1,1-diMethylethoxy)carbonyl]aMino]Methyl]cyclohexyl]-, phenylMethyl ester Cyclohexanol N-(3-AMino[1,1'-biphenyl]-4-yl)-carbaMic Acid tert-Butyl Ester tert-butyl (2-bromo-3-fluorophenyl)carbamate tert-Butyl(3-formylbicyclo[1.1.1]pentan-1-yl)carbamate tert-butyl (3-(hydroxymethyl)bicyclo[1.1.1]pentan-1-yl)carbamate tert-butyl (2,2,3,3-tetramethylcyclopropyl)carbamate tert-butyl (3,5-dibromopyrazin-2-yl)carbamate Methyl trans-4-(tert-butoxycarbonylamino)cyclohexanecarboxylate BOC-1,4-TRANS-ACHC-OH TERT-BUTYL TRANS-4-FORMYLCYCLOHEXYLCARBAMATE 4-Aminocyclohexanol

  • BOC-TRANS-4-AMINOCYCLOHEXANOL
  • TERT-BUTYL TRANS-4-HYDROXYCYCLOHEXYLCARBAMATE
  • N-T-BOC-TRANS-4-AMINO CYCLOHEXANOL
  • TRANS-4-N-BOC-AMINOCYCLOHEXANOL
  • TRANS-(4-HYDROXY-CYCLOHEXYL)-CARBAMIC ACID TERT-BUTYL ESTER
  • TRANS-4-BOC-AMINO-1-CYCLOHEXANOL
  • TRANS-4-BOC-AMINOCYCLOHEXANOL
  • TRANS-T-BUTYL-4-HYDROXYCYCLOHEXYLCARBAMATE
  • TRANS-N-BOC-4-AMINO-CYCLOHEXANOL
  • TRANS-N-4-BOC-AMINOCYCLOHEXANOL
  • trans-4-Aminocyclohexanol, N-BOC protected
  • trans-tert-Butyl-4-hydroxycyclohexylcarbamate
  • Boc-trans-4-aminocyclohexanol/CH63857
  • Boc-trans-4-aminocyclohexanol/CH85402
  • trans-4-Aminocyclohexanol, N-BOC protected 98%
  • trans-4-(tert-Butoxycarbonylamino)cyclohexanol
  • tert-butyl ((1r,4r)-4-hydroxycyclohexyl)carbaMate
  • 104582
  • tert-Butyl (trans-4-hydroxycyclohex-1-yl)carbamate, trans-4-[(tert-Butoxycarbonyl)amino]cyclohexan-1-ol
  • trans-4-Aminocyclohexan-1-ol, N-BOC protected 98%
  • CarbaMic acid, N-(trans-4-hydroxycyclohexyl)-, 1,1-diMethylethyl ester
  • N-(trans-4-Hydroxy-cyclohexyl)-carbamic acid tert-butyl ester
  • trans-4-Aminocyclohexan-1-ol,N-BOCprotected98%
  • <i>trans</i>-4-(<i>tert</i>-Butoxycarbonylamino)cyclohexanol
  • 4r)-4-hydroxycyclohexylcarbaMate
  • tert-butyl (1r
  • trans-4-(tert-Butoxycarbonylamino)cyclohexanol &gt
  • tert-butyl(trans-4-hydroxcyclohexyl)carbamate
  • trans-N-4-Boc-aminocyclohexanol, 98%
  • trans-4-Aminocyclohexan-1-ol, N-BOC protected
  • Trans-4-n-boc-aminocylohexanol
  • 111300-06-2
  • 11300-06-2
  • pharmacetical
  • API intermediates
  • pharmaceutical