2-Methylaziridine Property

Melting point:

-65°C

Boiling point:

66°C

Density 

0.8

refractive index 

1.4125

Flash point:

-4°C

storage temp. 

-20°C

solubility 

soluble in No data available

pka

pK1:8.18(+1) (25°C)

form 

Flammable liquid

Water Solubility 

miscible

Stability:

Unstable - readily polymerises in the absence of an inhibitor. May polymerize vigorously or explosively in the presence of acids. Flammable. Incompatible with acids, oxidizing agents, quinones, carbonyl compounds, sulfonyl halides, some types of plastic, water.

CAS DataBase Reference

75-55-8(CAS DataBase Reference)

NIST Chemistry Reference

Aziridine, 2-methyl-(75-55-8)

IARC

2B (Vol. 9, Sup 7, 71) 1999

EPA Substance Registry System

Propyleneimine (75-55-8)

Safety

Hazard Codes 

F;T+;N,T,F,N,T+,Xn

Risk Statements 

45-11-26/27/28-41-51/53-35-48/20/22-40-36/38-20/22-63-48/22-38-22

Safety Statements 

53-45-61-36/37/39-28-26-36/37

RIDADR 

1921

OEB

B

OEL

TWA: 2 ppm (5 mg/m3) [skin]

RTECS 

CM8050000

HazardClass 

3.1

PackingGroup 

I

Hazardous Substances Data

75-55-8(Hazardous Substances Data)

IDLA

100 ppm

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H300Fatal if swallowed

H310Fatal in contact with skin

H318Causes serious eye damage

H330Fatal if inhaled

H350May cause cancer

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

2-Methylaziridine Chemical Properties,Usage,Production

Chemical Properties

colourless oily fuming liquid

Chemical Properties

Propyleneimine is a fuming, colorless, oily liquid with a strong ammonia-like odor.

Uses

Intermediate in production of polymers, coatings, adhesives, textiles, and paper finishes.

Uses

The renal papillary toxin.

Definition

ChEBI: 2-Methylaziridine is a member of aziridines.

General Description

A clear colorless liquid with an ammonia-like odor. Flash point 25°F. Toxic by ingestion, inhalation and through skin absorption. Less dense than water. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Under prolonged exposure to fire or heat the containers may rupture violently and rocket. Used as an organic intermediate.

Air & Water Reactions

Highly flammable. Soluble in water. Reacts slowly and non hazardously with water to form propanolamine or methylethanolamine.

Reactivity Profile

PROPYLENEIMINE, [INHIBITED] is subject to violent polymerization on contact with an acid. (The inhibitor is intended to prevent polymerization). Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Hazard

Flammable, dangerous fire risk. Toxic by ingestion, inhalation, and skin absorption. Upper respiratory tract irritant and kidney damage. Possi- ble carcinogen.

Health Hazard

Toxic after acute exposure. Can severely irritate eyes, skin, and lungs.

Fire Hazard

Chemical is extremely flammable; vapors are heavier than air. Toxic oxides of nitrogen are produced during combustion. Avoid acids, strong oxidizers. Thermally unstable. Hazardous polymerization may occur. Contact with acid promotes violent polymerization.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Poison by ingestion and skin contact. Moderately toxic by inhalation. Mutation data reported. Severe eye irritant. Implicated as a brain carcinogen. A flammable liquid and very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. Polymerizes explosively on exposure to acids or acid fumes. A storage hazard. When heated to decomposition it emits toxic fumes of NOx.

Potential Exposure

Propyleneimine is used in the modifi- cation of latex surface coating resins; in the production of polymers for use in the paper and textile industries as coat- ings and adhesives.

Carcinogenicity

2-Methylaziridine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN1921 Propyleneimine, stabilized, Hazard Class: 3; Labels: 3-Flammable liquid, 6.1-Poisonous materials.

Incompatibilities

Vapors or liquid form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, water, carbonyl compounds; quinones, sulfonyl halides. May explode in heat. Subject to violent polymerization in contact with acids. Hydrolyzes in water to form methylethanolamine.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Controlled incineration (incinerator equipped with a scrubber or thermal unit to reduce nitrogen oxides emissions).