(R)-(-)-2-Chloromandelic acid

Product Name: (R)-(-)-2-Chloromandelic acid
CAS No.: 52950-18-2
Chemical Name: (R)-(-)-2-Chloromandelic acid
Synonyms: (R)-2-(2-Chlorophenyl)-2-hydroxyacetic acid;(R)-2-CHLOROMANDELIC ACID;L-2-Chloromandelic;R-Chloromadelic acid;(R)-(-)-2-Chloromand;(R-chloromandelicacid);2-CHLORO-D-MANDELIC ACID;(R)-(-)-2-Chloromandelic;(-)-2-Chloromandelic acid;2-CHLORO-MANDELIC ACID (R)
CBNumber: CB3715688
Molecular Formula: C8H7ClO3
Formula Weight: 186.59
MOL File: 52950-18-2.mol

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(R)-(-)-2-Chloromandelic acid Property

Melting point:: 119-121 °C(lit.)
alpha: -125 º (c=3, H2O)
Boiling point:: 266.91°C (rough estimate)
Density: 1.48
vapor pressure: 0Pa at 25℃
refractive index: -124.5 ° (C=3, H2O)
storage temp.: Sealed in dry,Room Temperature
solubility: Methanol
pka: 3.30±0.10(Predicted)
form: Solid
color: Off-White
optical activity: [α]23/D 126°, c = 3 in H2O
BRN: 2693370
LogP: 1.51 at 23℃
Surface tension: 48.7mN/m at 1g/L and 20℃
CAS DataBase Reference: 52950-18-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,C
Risk Statements: 36/37/38-43-41
Safety Statements: 37/39-26-24/25-36-36/37/39
WGK Germany: 3
HS Code: 29181990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 727067
Product name: (R)-(?)-2-Chloromandelic acid
Purity: ChiPros
Packaging: 5g
Price: $76
Updated: 2023/06/20

Sigma-Aldrich

Product number: 478873
Product name: (R)-(?)-2-Chloromandelic acid
Purity: 99%
Packaging: 500mg
Price: $154
Updated: 2023/06/20

TCI Chemical

Product number: C1663
Product name: 2-Chloro-D-mandelic Acid
Purity: >98.0%(T)
Packaging: 1g
Price: $21
Updated: 2025/07/31

TCI Chemical

Product number: C1663
Product name: 2-Chloro-D-mandelic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $59
Updated: 2025/07/31

Sigma-Aldrich

Product number: 727067
Product name: (R)-(?)-2-Chloromandelic acid
Purity: ChiPros
Packaging: 25g
Price: $263
Updated: 2024/03/01

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(R)-(-)-2-Chloromandelic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Clopidogrel intermediate.

Synthesis

74-90-8

89-98-5

10421-85-9

52923-20-3

First, 150 mL of toluene was added to a flask equipped with a stirrer and an internal thermometer. Under constant stirring, 0.09 g (0.08 x 10^-3 mol) of the (R,R)-VO salen complex of Example 1 and 21.1 g (0.15 mol) of freshly prepared 2-chlorobenzaldehyde were added sequentially. Subsequently, 10.1 g (0.375 mol) of hydrocyanic acid was added all at once. The resulting dark green homogeneous solution was stirred for 24 h at room temperature in a closed apparatus. The conversion was analyzed by gas chromatography (GC) to be 98% and the enantiomeric excess (ee) value of (S)-2-chloromandelate cyanohydrin was 73%.

References

[1] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
[2] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
[3] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
[4] Patent: US2004/236129, 2004, A1. Location in patent: Page 4
[5] Patent: US2004/236129, 2004, A1. Location in patent: Page 4

(R)-(-)-2-Chloromandelic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(-)-2-Chloromandelic acid Suppliers

Americas 1 Belgium 1 Canada 3 China 242 Europe 4 France 1 Germany 10 India 7 Japan 5 Singapore 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 2 United Kingdom 16 United States 46 Global 343

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View Lastest Price from (R)-(-)-2-Chloromandelic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (R)-(-)-2-Chloromandelic acid 52950-18-2
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%min
Supply Ability: 500kg
Release date: 2021-11-03

Hebei Chuanghai Biotechnology Co., Ltd

Product: (R)-(-)-2-Chloromandelic acid 52950-18-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-22

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-(-)-2-Chloromandelic acid 52950-18-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-14

52950-18-2, (R)-(-)-2-Chloromandelic acidRelated Search:

(S)-(+)-Mandelic acid Folic acid Ethyl 2-(Chlorosulfonyl)acetate 2-Chlorobenzyl chloride (S)-Amlodipine 2-Chloroaniline 2-Methylbenzyl chloride Mandelic acid alpha-Chloro-o-fluorotoluene Levetiracetam L-Menthol PALMITOLEIC ACID Citric acid Ascoric Acid P-CHLOROMANDELIC ACID,4-Chloromandelic acid,D/L-4'-CHLOROMANDELIC ACID,4-Chloromandelic acid, Pract. 2-Aminobenzylchloride o-chloromandelic acid,DL-2-CHLOROMANDELIC ACID,2-CHLOROMANDELIC ACID (R)-(-)-3-CHLOROMANDELIC ACID,(R)-3-CHLOROMANDELIC ACID

2-CHLORO-D-MANDELIC ACID

2-CHLORO-MANDELIC ACID (R)

(R)-(2-CHLORO-PHENYL)-HYDROXY-ACETIC ACID

(R)-(-)-2-CHLOROMANDELIC ACID

(R)-2-CHLOROMANDELIC ACID

(R)-2-CHLORO-ALPHA-HYDROXYPHENYLACETIC ACID

(R-chloromandelicacid)

(R)-ORTHO-CHLOROMANDELIC ACID

L-2-Chloromandelic

R-Chloromadelic acid

(R)-(-)-2-CHLOROMANDELIC ACID: CHIPROS 99%, EE 99%

(R)-(-)-2-CHLOROMANDELIC ACID 99%

(R )-(-)-2-chloromandellic acid

(R)-(-)-2-Chloromandelic acid, ChiPros 99+%, ee 99+%

(-)-o-Chloro-D-mandelic acid

(2R)-2-(2-Chlorophenyl)-2-hydroxyacetic acid

(R)-2-(2-Chlorophenyl)-2-hydroxyacetic acid

(R)-2-Hydroxy-2-(2-chlorophenyl)acetic acid

(R)-α-Hydroxy-2-chlorobenzeneacetic acid

[R,(-)]-o-Chloro-α-hydroxybenzeneacetic acid

(r)-2-chloro-à-hydroxyphenylacetic acid

(R)-(-)-2-Chloromandelic acid,99%

Benzeneacetic acid, 2-chloro-.alpha.-hydroxy-, (.alpha.R)-

(R)-(-)-2-Chloromandelic acid ,99% [ee 95%]

R-(-)-2-Chloromandelic acid ,98%

(R)-(-)-2-Chloromand

D-2-Chloromandelic Acid,99%e.e.

2-Chloro-D-mandelic Acid &gt

Benzeneacetic acid, 2-chloro-α-hydroxy-, (αR)-

(R)-(-)-2-ChloroMandelic acidr

TIANFU-CHEM (R)-(-)-2-Chloromandelic acid

R(-) -o-chlormandelic acid

(R)-(-)-2-Chloromandelic

(-)-2-Chloromandelic acid

R (-) - o-chloromandelic acid

R-(-)-chloro phenyl glycollic acid

(2R)-2-(2-chlorophenyl)-2-hydroxyethanoic acid

(<i>R</i>)-(?)-2-Chloromandelic acid

(R)-2-Chloro-2-phenylglycolicacid

52950-18-2

C8H7ClO3

Organic Building Blocks

Chiral Building Blocks

Asymmetric Synthesis

Carboxylic Acids

FINE Chemical & INTERMEDIATES

Carboxylic Acids

Chiral Building Blocks

Organic Building Blocks

chiral

API intermediates