Mandelic acid

Product Name: Mandelic acid
CAS No.: 611-71-2
Chemical Name: Mandelic acid
Synonyms: D-MANDELIC ACID;(R)-(-)-MANDELIC ACID;(R)-2-HYDROXY-2-PHENYLACETIC ACID;(R)-MANDELIC ACID;2-Hydroxy-2-phenylacetic acid;(R)-(-)-2-MANDELIC ACID;(-)-MANDELIC ACID;D-(-)-MANDELIC ACID;(-)-D-MANDELIC ACID;D-ALPHA-HYDROXYPHENYLACETIC ACID
CBNumber: CB9411418
Molecular Formula: C8H8O3
Formula Weight: 152.15
MOL File: 611-71-2.mol

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Mandelic acid Property

Melting point:: 131-133 °C(lit.)
alpha: -150 º (c=2.5, H2O)
Boiling point:: 214.6°C (rough estimate)
Density: 1.1677 (rough estimate)
refractive index: -153.5 ° (C=1, H2O)
Flash point:: >190℃
storage temp.: Store below +30°C.
solubility: 109.8g/l soluble
form: Crystalline Powder, Crystals or Flakes
pka: 3.37(at 25℃)
color: White to slightly yellow-beige
PH: 3.34(1 mM solution);2.75(10 mM solution);2.22(100 mM solution);
optical activity: [α]25/D 151°, c = 1 in ethanol
Water Solubility: It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol.
Sensitive: Light Sensitive
BRN: 2691094
Stability:: Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents.
InChIKey: IWYDHOAUDWTVEP-SSDOTTSWSA-N
LogP: 0.550 (est)
CAS DataBase Reference: 611-71-2(CAS DataBase Reference)
EPA Substance Registry System: Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (611-71-2)

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Safety

Hazard Codes: Xi
Risk Statements: 41-36/37/38
Safety Statements: 22-24/25-36-26-39-37/39
WGK Germany: 1
Hazard Note: Irritant/Light Sensitive
TSCA: Yes
HS Code: 29181980
Toxicity: LD50 orally in Rabbit: 5000 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.06914
Product name: (R)-(-)-Mandelic acid
Purity: for resolution of racemates for synthesis
Packaging: 25g
Price: $84.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.06914
Product name: (R)-(-)-Mandelic acid
Purity: for resolution of racemates for synthesis
Packaging: 100g
Price: $163
Updated: 2024/03/01

Sigma-Aldrich

Product number: 154210
Product name: (R)-(?)-Mandelic acid
Purity: ReagentPlus , ≥99%
Packaging: 5g
Price: $38.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 154210
Product name: (R)-(?)-Mandelic acid
Purity: ReagentPlus , ≥99%
Packaging: 25g
Price: $109
Updated: 2024/03/01

TCI Chemical

Product number: M0662
Product name: D-(-)-Mandelic Acid
Purity: >99.0%(GC)(T)
Packaging: 25g
Price: $56
Updated: 2024/03/01

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Mandelic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(R)-(-)-Mandelic acid, is used as a antiseptic ingredient particularly against urinary tract infections.Mandelic acid and its derivatives are used to apply the dual activities as an antibacterial agent and as an antiaging agent. It is used as an intermediate for the synthesis of target molecules for other applications.

Uses

(R)-(?)-Mandelic acid can be used:

As a chiral acid in the separation of diastereomeric salts for the synthesis of chiral pyridoindole based building block.
In the study of chiral acid selectivity of poly(3,4-ethylenedioxythiophene) (PEDOT) based chiral conducting?polymers.

Uses

Antiseptic (urinary).

Definition

ChEBI: (R)-mandelic acid is the (R)-enantiomer of mandelic acid. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a (R)-mandelate. It is an enantiomer of a (S)-mandelic acid.

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 2565, 1968 DOI: 10.1021/jo01270a105
Synthetic Communications, 18, p. 2141, 1988 DOI: 10.1080/00397918808068285

General Description

(R)-(-)-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (R,S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme.

Flammability and Explosibility

Non flammable

Purification Methods

Purify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]

Mandelic acid Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI)

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Mandelic acid Suppliers

Americas 1 Australia 1 Belgium 1 Canada 2 China 581 Europe 5 France 1 Germany 11 India 34 Japan 6 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 1 Ukraine 2 United Kingdom 12 United States 62 Global 727

-Shijiazhuang Hanhong Chemical Co., Ltd.

Tel: 0311-82576889 18203206564
Fax: 0311-82576889
Email: 18203206564@163.com
Country: China
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
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Nanjing Gold Pharmaceutical Technology Co. Ltd.

Tel: 025-84209270; 15905158493
Fax: 025-84209270
Email: wgp@nanjing-pharmaceutical.com
Country: China
ProdList: 63
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Nantong Jiaxingtai Biotechnology Co., Ltd.

Tel: 18795782766
Email: 769011731@qq.com
Country: China
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Shouguang Jiasheng Chemical Co., Ltd.

Tel: 0536-7971999 18232719690
Fax: 0536-7971999
Email: sgjiasheng@hotmail.com
Country: China
ProdList: 399
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Shanghai ideal Industrial Co., Ltd.

Tel: 021-58957966 18930537195
Fax: 021-60899437
Email: wouchina@126.com
Country: China
ProdList: 3033
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Beijing Hezhicheng Chemical Products Co., Ltd

Tel: 18311365218
Email: sales@toachem.com
Country: China
ProdList: 120
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Qingdao Baiyi Chemical Co., Ltd

Tel: 13953303907 13953303907
Email: 2338367690@qq.com
Country: China
ProdList: 446
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J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
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View Lastest Price from Mandelic acid manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Mandelic acid 611-71-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 1000 kg
Release date: 2024-04-08

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: Mandelic acid 611-71-2
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 99
Supply Ability: 20tons
Release date: 2024-02-06

Sigma Audley

Product: Mandelic acid 611-71-2
Price: US $35.00-25.00/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 200tons/year
Release date: 2024-03-15

611-71-2, Mandelic acidRelated Search:

Citric acid PHENYL VALERATE Hyaluronic acid 4-Chloromandelic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid Glycolic acid CHLOROPHOSPHONAZO III Phenylboronic acid 5-Pyrazolecarboxylic acid Ascoric Acid (S)-(+)-Mandelic acid 2-Chloromandelic acid Benactyzine Flurenol-butyl 3-Quinuclidinyl benzilate (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid Acetic anhydride

(R)-(-)-2-MANDELIC ACID

(R)-2-HYDROXY-2-PHENYLACETIC ACID

(R)-(-)-AMYGDALIC ACID

(R)-ALPHA-HYDROXYPHENYLACETIC ACID

R-(-)-ALPHA-HYDROXYPHENYLACETIC ACID

(R)-(-)-MANDELIC ACID

(R)-MANDELIC ACID

D-ALPHA-HYDROXYPHENYLACETIC ACID

D-A-HYDROXYPHENYLACETIC ACID

D-2-HYDROXY-PHENYLACETIC ACID

D-(-)-AMYGDALIC ACID

D-AMYGDALIC ACID

D-PHENYLGLYCOLIC ACID

(-)-D-MANDELIC ACID

D-(-)-MANDELIC ACID

D-MANDELIC ACID

L-2-hydroxy-2-phenylacetic acid

D(-)-MANDELIC ACID FOR RESOLUTION &

(R)-(-)-MANDELIC ACID, 99+%

(R)-(-)-MANDELIC ACID, 98% (99% EE/GLC)

(R)-(-)-MANDELIC ACID 99%

D-(-)-α-Hydroxybenzeneacetic acid

ALPHAR-HYDROXY-BENZENEACETIC ACID

(-)-MANDELIC ACID

D-Mandelic acid or R-(-)Mandelic acid

Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)-

(r)-(-)-à-hydroxyphenylacetic acid

D-mandelic acid(R-mandelic acid)

(R)-alpha-Hydrophenylacetic acid

D-(-)-Mandelic acid 98%

L-2-Hydroxy-2-phenylessigsure

D-minus-mandelic acid sigma grade

[R,(-)]-α-Hydroxybenzeneacetic acid

D-()-Mandelic acid,(R)-α-Hydroxyphenylacetic acid

(R)-(-)-Mandelic acid, ChiPros\(tm, 99+% ee 99+%

)-Mandel

(R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-Hydroxy(phenyl)ethanoic acid, D-(-)-Phenylglycolic acid

(R)-Alfa-hydroxyphenylacetic acid

(R)-()-Mandel

(R)-(-)-Mandelic acid, 99% 25GR

(R)-(-)-Mandelic acid, 98% e.e.

(R)-(-)-MANDELIC ACID FOR RESOLUTION OF

(R)-2-Phenylglycolic acid

(R)-alpha-Hydroxy-benzeneacetic acid

Sertraline EP IMpurity E

(R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-2-Hydroxy-2-phenylethanoic acid, D-(-)-Phenylglycolic acid

(R)-(-)-Mandelic acid, ChiPros 99+%, ee 99+%

D-MANDELIC ACID extrapure

(2R)-2-Hydroxy-2-phenylacetic acid

(R)-a-Hydroxybenzeneacetic acid

(R)-a-Hydroxyphenylacetic acid

D-2-Phenylglycolic acid

(R)-(-)-MANDELIC ACID: CHIPROS 99%, EE 99%

2-Hydroxy-2-phenylacetic acid

2-Phenylglycolic acid

a-Hydroxy-benzeneacetic acid

alpha-Hydroxyphenylacetic acid

Hydroxy(phenyl)acetic acid