ChemicalBook > CAS DataBase List > ASTRAGALIN

ASTRAGALIN

Overview source

Product Name: ASTRAGALIN
CAS No.: 480-10-4
Chemical Name: ASTRAGALIN
Synonyms: KAEMPFEROL-3-O-GLUCOSIDE;astragaline;Kaempferol 3-O-β-D-glucopyranoside;KAEMPFEROL-3-GLUCOSIDE;k5;Astragalin ,98%;kaempferol 3-O-beta-D-glucoside;Kaempferol 3-β-D-glucopyranoside;KAEMPFEROL-3-O-BETA-D-GLUCOPYRANOSIDE;5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
CBNumber: CB3732744
Molecular Formula: C21H20O11
Formula Weight: 448.38
MOL File: 480-10-4.mol

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ASTRAGALIN Property

Melting point:: 223-229°C
Boiling point:: 823.2±65.0 °C(Predicted)
Density: 1.79±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
pka: 6.20±0.40(Predicted)
form: Solid
color: Yellow
biological source: mouse
InChIKey: JPUKWEQWGBDDQB-QSOFNFLRSA-N
SMILES: O=C1C(=C(C2C=CC(O)=CC=2)OC2=CC(O)=CC(O)=C12)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:21,22,23,25,27,r|
LogP: 1.950 (est)
CAS DataBase Reference: 480-10-4(CAS DataBase Reference)

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Safety

Safety Statements: 22
WGK Germany: 3
RTECS: DJ3080000
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SAB5300267
Product name: Monoclonal Anti-Cytokeratin 5 antibody produced in mouse
Purity: clone 2C2, purified immunoglobulin, buffered aqueous solution
Packaging: 100μg
Price: $541
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHL89237
Product name: Kaempferol 3-glucoside
Purity: phyproof<SUP>®</SUP> Reference Substance
Packaging: 10 mg
Price: $549
Updated: 2025/07/31

Sigma-Aldrich

Product number: 04500585
Product name: Kaempferol 3-glucoside
Purity: primary pharmaceutical reference standard
Packaging: 10mg
Price: $515
Updated: 2025/07/31

Sigma-Aldrich

Product number: SAB5300265
Product name: Monoclonal Anti-Cytokeratin 5 antibody produced in mouse
Purity: clone 1E1, ascites fluid
Packaging: 100μL
Price: $466
Updated: 2022/05/15

Sigma-Aldrich

Product number: 68437
Product name: Kaempferol 3-glucoside
Purity: analytical standard
Packaging: 5MG
Price: $568
Updated: 2022/05/15

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ASTRAGALIN Chemical Properties,Usage,Production

Overview

Astragalin is a chemical compound. It can be isolated from Phytolacca americana (the American pokeweed) or in the methanolic extract of fronds of the fern Phegopteris connectilis.t is also found in wine.

source

Astragalin belongs to the class of organic compounds known as flavonoid-3-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C3-position. Astragalin exists as a solid, slightly soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, astragalin is primarily located in the cytoplasm. Astragalin can be converted into astragalin heptaacetate and 2''-acetylastragalin. Outside of the human body, astragalin can be found in a number of food items such as tamarind, american cranberry, chickpea, and bilberry. This makes astragalin a potential biomarker for the consumption of these food products.

Chemical Properties

Yellow solid powder

Uses

Astragaline is found in Erica multiflora leaf extract, which is used for mitigating high-?fat and high-?fructose diet (HFFD)?-?induced metabolic syndrome.

Definition

ChEBI: A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage.

Biological Activity

Similar kaempferol glycosides reduce food intake and corresponding weight gain in Wistar rats.The glucoside was not tested.

in vivo

Astragalin (25, 50, and 75 mg/kg; p.o.; once every two days; 25 d) reduces the tumor volumes, tumor weight and tumor formation rates and decreases expression of p-NFκB and p-iκκα in nude mouse model?with human colon cancer^[1].

Animal Model:	Male BALB/c nude mice (4-week-old) with HCT116 cells (s.c.)^[1]
Dosage:	0 mg/kg, 25 mg/kg, 50 mg/kg, 75 mg/kg
Administration:	Oral gavage; once every two days; for 25 days
Result:	Resulted tumor inhibition rates of 17.43%, 34.89% (p?< 0.01), and 67.06% with 25 mg/kg, 50 mg/kg, 75 mg/kg dose administration. Showed no effect on mouse weight.

IC 50

p65

ASTRAGALIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ASTRAGALIN manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: ASTRAGALIN 480-10-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 MT
Release date: 2024-11-14

Shaanxi Haibo Biotechnology Co., Ltd

Product: Astragalin 480-10-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-09-01

Shanghai Standard Technology Co., Ltd.

Product: Astragaline 480-10-4
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-03

480-10-4, ASTRAGALINRelated Search:

Jaceosidin Pterostilbene SHIONONE taxusin Perillartine (-)-PERILLALDEHYDE Palmitic acid HYPOCRELLIN B Chonglou Saponin II Paclitaxel Rutin ISORHAMNETIN-3-RUTINOSIDE QUERCETIN-3-O-BETA-D-GLUCOPYRANOSYL-6''-ACETATE TILIROSIDE ASTRAGALIN ASTRAGALIN(KAEMPFEROL-3-O-GLUCOSIDE)(P) Astragalin Astragaloside II Kaempferol

KAEMPFEROL-3-O-BETA-D-GLUCOPYRANOSIDE

KAEMPFEROL-3-O-GLUCOSIDE

KAEMPFEROL-3-GLUCOSIDE

ASTRAGALIN

4h-1-benzopyran-4-one,3-(beta-d-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyp

astragaline

3-(β-D-Glucopyranosyloxy)-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Kaempferol 3-β-D-glucopyranoside

EBS2

KRT5

KRT5A

Monoclonal Anti-Cytokeratin 5 antibody produced in mouse

58 kDa cytokeratin

Anti-Keratin 5, C-Terminal antibody produced in rabbit

Cytokeratin-5

Keratin type II cytoskeletal 5

kaempferol 3-O-beta-D-glucoside

kaempferol-3-beta-glucopyranoside

kaempferol-3-beta-monoglucoside

kaempferol-3-d-glucoside

KAEMPFEROL-3-O-GLUCOSIDE WITH HPLC

Kaempferol-3-glucoside 97%

ASTRAGALIN hplc

5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

Astragalin ,98%

3-GlucosylkaeMpferol

4',5,7-Trihydroxyflavone 3-β-D-glucopyranoside

KaeMpferol 3-O-glucopyranoside

Kaempferol 3-β-glucopyranoside

Kaempferol 3-β-monoglucoside

5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-4-one

ASTRAGALIN;KAEMPFEROL 3-Β-D-GLUCOPYRANOSIDE

Kaempferol-3-O-Glucoside (Astragaline)

4H-1-Benzopyran-4-one, 3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-

Kaempferol 3-beta-D-glucopyranoside >=97.0% (HPLC)

Kaempferol 3-O-β-D-glucopyranoside

5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

TIANFU-CHEM - ASTRAGALIN

Kaempferol 3-O-glucopyranoside（Astragalin ）

kaempferol-3-O-β-D-glucoside

Kaempferol-3-beta-D-glucopyranoside

Kaempferol 3-glucoside-RM

2,4-Dichlorobenzyl Alcohol Impurity 6 (2,4-Dichlorobenzyl Alcohol EP Impurity F)

Astragalin, 10 mM in DMSO

Kaempferol 3-β-<sc>D</sc>-glucopyranoside

DDD1

480-10-4

48061064

480104

Flavonoids

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

chemical reagent

pharmaceutical intermediate

phytochemical

Tetra-substituted Flavones