ChemicalBook > CAS DataBase List > SHIONONE
SHIONONE
Uses- Product Name
- SHIONONE
- CAS No.
- 10376-48-4
- Chemical Name
- SHIONONE
- Synonyms
- Shionon;SHIONONE;Shionone ,98%;21-Shionen-3-one;18,19-Seco-D:A-friedolup-19-en-3-one;Shionone, 98%, from Aster tataricus L. f.;2(1H)-Chrysenone,hexadecahydro-1,4b,6a,8,10a,12a-;hexamethyl-8-(4-methyl-3-pentenyl)-,(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-;3β,5,8,17aβ-Tetramethyl-3-(4-methyl-3-pentenyl)-D-homo-5α-androstan-17-one;(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-Hexadecahydro-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methyl-3-penten-1-yl)-2(1H)-chrysenone
- CBNumber
- CB4100234
- Molecular Formula
- C30H50O
- Formula Weight
- 426.72
- MOL File
- 10376-48-4.mol
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SHIONONE Property
- Melting point:
- 161-162°
- alpha
- D26.5 -56.1° (c = 1.07 in chloroform)
- Boiling point:
- 485.6±14.0 °C(Predicted)
- Density
- 0.941±0.06 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- color
- White to off-white
- optical activity
- -56.126.5 (c 1.07, CHCl3)
- LogP
- 10.401 (est)
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Safety
- Safety Statements
- 24/25
- HS Code
- 29143990
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N-Bromosuccinimide Price
TRC
- Product number
- S357700
- Product name
- Shionone
- Packaging
- 10mg
- Price
- $130
- Updated
- 2021/12/16
Usbiological
- Product number
- 300969
- Product name
- Shionone
- Packaging
- 20mg
- Price
- $581
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 72324
- Product name
- Shionone
- Packaging
- 100mg
- Price
- $1460
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb594300
- Product name
- Shionone
- Packaging
- 20mg
- Price
- $340
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PXT0000590
- Product name
- SHIONONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.97
- Updated
- 2021/12/16
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SHIONONE Chemical Properties,Usage,Production
Uses
Shionone is an effective inhibitor of human neutrophil elastase which may be used as a treatment for inflammatory lung diseases including H1N1 and SARS virus infections.
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Aster tataricus.
Uses
Shionone is an effective inhibitor of human neutrophil elastase which may be used as a treatment for inflammatory lung diseases including H1N1 and SARS virus infections.
Definition
ChEBI: A tetracyclic triterpenoid that is perhydrochrysene which is substituted by methyl groups at positions 1, 4bbeta, 6aalpha, 8beta, 10abeta and 12a positions, by a 4-methylpent-3-enyl group t the 8alpha position, and with an oxo group at position 2.
in vivo
Shionone (orally administration; 80 mg/kg; 3 days; once daily) shows the trend of enhancing sputum secreting, but has no effect on ammonia-induced cough and reduces xylene-induced ear edema[1].
| Animal Model: | ICR male mice[1] |
| Dosage: | 80 mg/kg |
| Administration: | Orally administration; 3 days; once daily |
| Result: | Reduced the ear edema for 11.3% by use shionone. |
target
ERK | IkB | NOS | IKK
SHIONONE Preparation Products And Raw materials
Raw materials
Preparation Products
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SHIONONE Suppliers
- Tel
- +86-21-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
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- 6003
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- 61
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- 400-6009262 16621234537
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- 021-64823266
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- China
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- 0871-65217109 13211707573;
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- 0871-65215563
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- China
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- 4008-755-333 18080918076
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- 028-86757656
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- China
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- +86-28-82633165
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- China
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- +86-21-65211385-8001 36031160
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- China
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- China
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- 021-021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
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- 7783
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- Tel
- 028-82610909 13388174823
- Fax
- 8171-1798
- scglp@glp-china.com
- Country
- China
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- 1064
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View Lastest Price from SHIONONE manufacturers
Shanghai Standard Technology Co., Ltd.
- Product
- Shionone 10376-48-4
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-10-28
Career Henan Chemical Co
- Product
- SHIONONE 10376-48-4
- Price
- US $1.00/kg
- Min. Order
- 1 mg
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-25
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