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SHIONONE

Uses

Product Name: SHIONONE
CAS No.: 10376-48-4
Chemical Name: SHIONONE
Synonyms: Shionon;SHIONONE;Shionone ,98%;21-Shionen-3-one;18,19-Seco-D:A-friedolup-19-en-3-one;Shionone, 98%, from Aster tataricus L. f.;2(1H)-Chrysenone,hexadecahydro-1,4b,6a,8,10a,12a-;hexamethyl-8-(4-methyl-3-pentenyl)-,(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-;3β,5,8,17aβ-Tetramethyl-3-(4-methyl-3-pentenyl)-D-homo-5α-androstan-17-one;(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-Hexadecahydro-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methyl-3-penten-1-yl)-2(1H)-chrysenone
CBNumber: CB4100234
Molecular Formula: C30H50O
Formula Weight: 426.72
MOL File: 10376-48-4.mol

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SHIONONE Property

Melting point:: 161-162°
alpha: D26.5 -56.1° (c = 1.07 in chloroform)
Boiling point:: 485.6±14.0 °C(Predicted)
Density: 0.941±0.06 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
color: White to off-white
optical activity: -56.126.5 (c 1.07, CHCl3)
LogP: 10.401 (est)

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Safety

Safety Statements: 24/25
HS Code: 29143990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S357700
Product name: Shionone
Packaging: 10mg
Price: $130
Updated: 2021/12/16

Usbiological

Product number: 300969
Product name: Shionone
Packaging: 20mg
Price: $581
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 72324
Product name: Shionone
Packaging: 100mg
Price: $1460
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594300
Product name: Shionone
Packaging: 20mg
Price: $340
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0000590
Product name: SHIONONE
Purity: 95.00%
Packaging: 5MG
Price: $496.97
Updated: 2021/12/16

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SHIONONE Chemical Properties,Usage,Production

Uses

Shionone is an effective inhibitor of human neutrophil elastase which may be used as a treatment for inflammatory lung diseases including H1N1 and SARS virus infections.

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Aster tataricus.

Uses

Shionone is an effective inhibitor of human neutrophil elastase which may be used as a treatment for inflammatory lung diseases including H1N1 and SARS virus infections.

Definition

ChEBI: A tetracyclic triterpenoid that is perhydrochrysene which is substituted by methyl groups at positions 1, 4bbeta, 6aalpha, 8beta, 10abeta and 12a positions, by a 4-methylpent-3-enyl group t the 8alpha position, and with an oxo group at position 2.

in vivo

Shionone (orally administration; 80 mg/kg; 3 days; once daily) shows the trend of enhancing sputum secreting, but has no effect on ammonia-induced cough and reduces xylene-induced ear edema^[1].

Animal Model:	ICR male mice^[1]
Dosage:	80 mg/kg
Administration:	Orally administration; 3 days; once daily
Result:	Reduced the ear edema for 11.3% by use shionone.

target

ERK | IkB | NOS | IKK

SHIONONE Preparation Products And Raw materials

Raw materials

Preparation Products

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SHIONONE Suppliers

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View Lastest Price from SHIONONE manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Shionone 10376-48-4
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-28

Career Henan Chemical Co

Product: SHIONONE 10376-48-4
Price: US $1.00/kg
Min. Order: 1 mg
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-25

10376-48-4, SHIONONERelated Search:

PURPURIN FRIEDELAN-3BETA-OL 5,7-Dihydrox -4'-methoxyisoflavone ASTRAGALIN roburic acid Madecassoside Pachymic acid Terrestrosin D Carboxyatractyloside Terrestrosin K dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate Madecassic acid taxusin Perillartine (-)-PERILLALDEHYDE Jaceosidin Paclitaxel Pterostilbene

SHIONONE

2(1H)-Chrysenone,hexadecahydro-1,4b,6a,8,10a,12a-

hexamethyl-8-(4-methyl-3-pentenyl)-,(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-

18,19-Seco-D:A-friedolup-19-en-3-one

3β,5,8,17aβ-Tetramethyl-3-(4-methyl-3-pentenyl)-D-homo-5α-androstan-17-one

Shionone ,98%

21-Shionen-3-one

Shionone, 98%, from Aster tataricus L. f.

Shionon

2(1H)-Chrysenone, hexadecahydro-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methyl-3-penten-1-yl)-, (1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-

(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methylpent-3-enyl)-1,3,4,4a,5,6,7,9,10,10b,11,12-dodecahydrochrysen-2-one

(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-Hexadecahydro-1,4b,6a,8,10a,12a-hexamethyl-8-(4-methyl-3-penten-1-yl)-2(1H)-chrysenone

10376-48-4

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract