ASTRAGALIN
Overview source- Product Name
- ASTRAGALIN
- CAS No.
- 480-10-4
- Chemical Name
- ASTRAGALIN
- Synonyms
- KAEMPFEROL-3-O-GLUCOSIDE;astragaline;Kaempferol 3-O-β-D-glucopyranoside;KAEMPFEROL-3-GLUCOSIDE;k5;Astragalin ,98%;kaempferol 3-O-beta-D-glucoside;Kaempferol 3-β-D-glucopyranoside;KAEMPFEROL-3-O-BETA-D-GLUCOPYRANOSIDE;5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
- CBNumber
- CB3732744
- Molecular Formula
- C21H20O11
- Formula Weight
- 448.38
- MOL File
- 480-10-4.mol
ASTRAGALIN Property
- Melting point:
- 223-229°C
- Boiling point:
- 823.2±65.0 °C(Predicted)
- Density
- 1.79±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
- pka
- 6.20±0.40(Predicted)
- form
- Solid
- color
- Yellow
- biological source
- mouse
- InChIKey
- JPUKWEQWGBDDQB-QSOFNFLRSA-N
- SMILES
- O=C1C(=C(C2C=CC(O)=CC=2)OC2=CC(O)=CC(O)=C12)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:21,22,23,25,27,r|
- LogP
- 1.950 (est)
- CAS DataBase Reference
- 480-10-4(CAS DataBase Reference)
Safety
- Safety Statements
- 22
- WGK Germany
- 3
- RTECS
- DJ3080000
- HS Code
- 29389090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SAB5300267
- Product name
- Monoclonal Anti-Cytokeratin 5 antibody produced in mouse
- Purity
- clone 2C2, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $541
- Updated
- 2025/07/31
- Product number
- PHL89237
- Product name
- Kaempferol 3-glucoside
- Purity
- phyproof<SUP>®</SUP> Reference Substance
- Packaging
- 10 mg
- Price
- $549
- Updated
- 2025/07/31
- Product number
- 04500585
- Product name
- Kaempferol 3-glucoside
- Purity
- primary pharmaceutical reference standard
- Packaging
- 10mg
- Price
- $515
- Updated
- 2025/07/31
- Product number
- SAB5300265
- Product name
- Monoclonal Anti-Cytokeratin 5 antibody produced in mouse
- Purity
- clone 1E1, ascites fluid
- Packaging
- 100μL
- Price
- $466
- Updated
- 2022/05/15
- Product number
- 68437
- Product name
- Kaempferol 3-glucoside
- Purity
- analytical standard
- Packaging
- 5MG
- Price
- $568
- Updated
- 2022/05/15
ASTRAGALIN Chemical Properties,Usage,Production
Overview
Astragalin is a chemical compound. It can be isolated from Phytolacca americana (the American pokeweed) or in the methanolic extract of fronds of the fern Phegopteris connectilis.t is also found in wine.
source
Astragalin belongs to the class of organic compounds known as flavonoid-3-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C3-position. Astragalin exists as a solid, slightly soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, astragalin is primarily located in the cytoplasm. Astragalin can be converted into astragalin heptaacetate and 2''-acetylastragalin. Outside of the human body, astragalin can be found in a number of food items such as tamarind, american cranberry, chickpea, and bilberry. This makes astragalin a potential biomarker for the consumption of these food products.
Chemical Properties
Yellow solid powder
Uses
Astragaline is found in Erica multiflora leaf extract, which is used for mitigating high-?fat and high-?fructose diet (HFFD)?-?induced metabolic syndrome.
Definition
ChEBI: A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage.
Biological Activity
Similar kaempferol glycosides reduce food intake and corresponding weight gain in Wistar rats.The glucoside was not tested.
in vivo
Astragalin (25, 50, and 75 mg/kg; p.o.; once every two days; 25 d) reduces the tumor volumes, tumor weight and tumor formation rates and decreases expression of p-NFκB and p-iκκα in nude mouse model?with human colon cancer[1].
| Animal Model: | Male BALB/c nude mice (4-week-old) with HCT116 cells (s.c.)[1] |
| Dosage: | 0 mg/kg, 25 mg/kg, 50 mg/kg, 75 mg/kg |
| Administration: | Oral gavage; once every two days; for 25 days |
| Result: | Resulted tumor inhibition rates of 17.43%, 34.89% (p?< 0.01), and 67.06% with 25 mg/kg, 50 mg/kg, 75 mg/kg dose administration. Showed no effect on mouse weight. |
IC 50
p65
ASTRAGALIN Preparation Products And Raw materials
Raw materials
Preparation Products
ASTRAGALIN Suppliers
- Tel
- --
- Fax
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- Country
- India
- ProdList
- 2
- Advantage
- 58
View Lastest Price from ASTRAGALIN manufacturers
- Product
- ASTRAGALIN 480-10-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100 MT
- Release date
- 2024-11-14
- Product
- Astragalin 480-10-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-09-01
- Product
- Astragaline 480-10-4
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-12-03