TOFISOPAM

Product Name: TOFISOPAM
CAS No.: 22345-47-7
Chemical Name: TOFISOPAM
Synonyms: SERIEL;Tosopam;EGYT 341;TOFISOPAM;tofizopam;grandaxin;Tofisopam, >=99%;TOFISOPAM 22345-47-7;7-CHLORO-1-METHYL-5-PHENYL-1,5-BENZODIAZEPINE-2,4-DIONE;-5-ethyl-7,8-dimethoxy-4-methyl-5H-benzo[d][1,2]diazepine
CBNumber: CB3738807
Molecular Formula: C22H26N2O4
Formula Weight: 382.45
MOL File: 22345-47-7.mol

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TOFISOPAM Property

Melting point:: 155-159°C
Boiling point:: 509.61°C (rough estimate)
Density: 1.2098 (rough estimate)
refractive index: 1.6500 (estimate)
solubility: DMSO: ~14 mg/mL
form: solid
pka: 7.29±0.40(Predicted)
color: white
λmax: 310nm(MeOH)(lit.)
Merck: 14,9503
Stability:: Hygroscopic

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-50
Safety Statements: 60-61
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: DE9540000
HS Code: 2933.99.8290
HazardClass: 6.1(b)
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T8200
Product name: Tofisopam
Purity: ≥98% (HPLC), solid
Packaging: 10mg
Price: $176
Updated: 2024/03/01

Sigma-Aldrich

Product number: T8200
Product name: Tofisopam
Purity: ≥98% (HPLC), solid
Packaging: 50mg
Price: $558
Updated: 2024/03/01

TCI Chemical

Product number: T3509
Product name: Tofisopam
Purity: >98.0%(HPLC)
Packaging: 50mg
Price: $84
Updated: 2024/03/01

TCI Chemical

Product number: T3509
Product name: Tofisopam
Purity: >98.0%(HPLC)
Packaging: 250mg
Price: $253
Updated: 2024/03/01

Cayman Chemical

Product number: 22026
Product name: Tofisopam
Purity: ≥95%
Packaging: 1mg
Price: $73
Updated: 2024/03/01

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TOFISOPAM Chemical Properties,Usage,Production

Originator

Grandaxine,Ozothine,France,1975

Uses

Tofisopam is a reagent used in preparation of allosteric ligands for pharmacological dark receptors GPR68 and GPR65. An anticonvulsant.

Definition

ChEBI: Tofisopam is an organic molecular entity.

Manufacturing Process

A mixture of 38.6 g (0.1 mol) of 3,4,3',4'-tetramethoxy-6-(α-acetopropyl)- benzophenone, 5.5 g (0.11 mol) of 100% hydrazine hydrate or 3.52 g (0.11 mol) of hydrazine, and 500 ml of absolute ethanol is boiled for 5 hours. After adding 100 ml of benzene, 400 ml of solvent mixture is distilled off from the reaction mixture by slow boiling for 3 hours. After cooling for 8 hours, 19 g of 5H-2,3-benzodiazepine derivative are separated from the residue as small, white crystals. The melting point is 133°C to 136°C (after recrystallizing from absolute ethanol, 136°C)

Therapeutic Function

Tranquilizer

TOFISOPAM Preparation Products And Raw materials

Raw materials

Preparation Products

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TOFISOPAM Suppliers

China 79 Germany 2 India 9 Italy 1 Japan 2 Switzerland 1 United Kingdom 2 United States 10 USA 1 Global 107

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

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ProdList: 38632
Advantage: 58

Cayman Chemical Company

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Country: United States
ProdList: 6213
Advantage: 81

United States Biological

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ProdList: 6214
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Riedel-de Haen AG

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ProdList: 6773
Advantage: 87

TCI America

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Country: United States
ProdList: 6909
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Matrix Scientific

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Country: United States
ProdList: 6632
Advantage: 80

Waterstone Technology, LLC

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Country: United States
ProdList: 6786
Advantage: 30

2A PharmaChem USA

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Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

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Country: United States
ProdList: 6718
Advantage: 47

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View Lastest Price from TOFISOPAM manufacturers

Shijiazhuang tongyang Import and Export Co., LTD

Product: TOFISOPAM 22345-47-7
Price: US $10.00/KG
Min. Order: 1g
Purity: 99
Supply Ability: 100kg/kg
Release date: 2021-08-10

Cangzhou Wanyou New Material Technology Co.,Ltd

Product: TOFISOPAM 22345-47-7 22345-47-7
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 300 Ton/Tons per Month china raw material pharmaceutical Tofisopam
Release date: 2019-04-22

Career Henan Chemical Co

Product: TOFISOPAM 22345-47-7
Price: US $14.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 50KG
Release date: 2018-07-23

22345-47-7, TOFISOPAMRelated Search:

3-[2-(3,4-dimethoxybenzoyl)-4,5-dimethoxyphenyl]pentan-2-one Toffee-related impurities (S)-Tofisopam (R)-Tofisopam ACETONE AZINE Acetophenone, 3-hydroxy-, hydrazone (6CI,7CI,8CI) TOFISOPAM

TOFISOPAM

7,8-DIMETHOXY-1-(3,4-DIMETHOXYPHENYL)-5-ETHYL-4-METHYL-5H-2,3-BENZODIAZEPINE

1-(3,4-Dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-benzo[d][1,2]diazepine

Tosopam

TOFISOPAM 22345-47-7

1-(3,4-Dimethoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine

5H-2,3-Benzodiazepine, 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl- (8CI, 9CI)

tofizopam

7-CHLORO-1-METHYL-5-PHENYL-1,5-BENZODIAZEPINE-2,4-DIONE

EGYT 341, Seriel, 7,8-Dimethoxy-1-(3,4-dimethoxyphenyl)-5-ethyl-4-methyl-5H-2,3-benzodiazepine

EGYT 341

1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine

1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-3-benzodiazepine

grandaxin

Tofisopam, >=99%

-5-ethyl-7,8-dimethoxy-4-methyl-5H-benzo[d][1,2]diazepine

SERIEL

1-[3,4-Bis(methyloxy)phenyl]-5-ethyl-4-methyl-7,8-bis(methyloxy)-5H-2,3-benzodiazepine

1-(3,4-DiMethoxyphenyl)-5-ethyl-7,8-diMethoxy-4-Methyl-5H-2,3-benzodiazepine (TofisopaM)

5H-2,3-Benzodiazepine, 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-

TofisopamQ: What is Tofisopam Q: What is the CAS Number of Tofisopam Q: What is the storage condition of Tofisopam Q: What are the applications of Tofisopam

22345-47-7

C22H26N2O4