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HEXOBARBITAL

Product Name
HEXOBARBITAL
CAS No.
56-29-1
Chemical Name
HEXOBARBITAL
Synonyms
EVIPAL;Dorico;Evipan;Toleran;Hexenal;Citodon;Citopan;Cyclopan;Narcosan;Sombulex
CBNumber
CB3744680
Molecular Formula
C12H16N2O3
Formula Weight
236.27
MOL File
56-29-1.mol
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HEXOBARBITAL Property

Melting point:
145-147°
Boiling point:
378.73°C (rough estimate)
Density 
1.1623 (rough estimate)
refractive index 
1.5460 (estimate)
Flash point:
11 °C
storage temp. 
2-8°C
pka
7.99±0.10(Predicted)
Water Solubility 
434.7mg/L(25 ºC)
EPA Substance Registry System
Hexobarbital (56-29-1)
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
22-39/23/24/25-23/24/25-11
Safety Statements 
36/37/39-45-36/37-16-7
RIDADR 
3249
WGK Germany 
3
RTECS 
CQ2625000
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H-013
Product name
Hexobarbital solution
Purity
1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$26.6
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0008991
Product name
HEXOBARBITAL
Purity
95.00%
Packaging
250G
Price
$4717.6
Updated
2021/12/16
AHH
Product number
MT-12878
Product name
Evipal
Purity
98%
Packaging
250g
Price
$428
Updated
2021/12/16
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HEXOBARBITAL Chemical Properties,Usage,Production

Description

Hexobarbital, 5-(cyclohexen-1- yl)-1,5-dimethylbarbituric acid,Mr 236.26. The acid forms colorless crystals that turn pink on exposure to light, mp 146 ?C. A 10 % aqueous solution of the sodium salt, Mr 258.25, has a pH of 11.5.

Chemical Properties

White crystals.

Uses

Medicine (sedative).

Definition

ChEBI: A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.

brand name

Cyclonal sodium;Cyclopan;Dorico soluble;Eviderm;Evipal sodium;Evipanl;Hexanal;Hexanastab oral.

World Health Organization (WHO)

Hexobarbital is a short-acting barbiturate. See WHO comment for barbiturates.

Clinical Use

Methohexital sodium is a short-acting anesthetic administered intravenously. It is very potent and has the shortest duration of action among the barbiturates used. A disturbing factor is that rather frequently it causes hiccups directly after injection. Patients are reported to recover rapidly from anesthesia. Abuse can lead to addiction.

Synthesis

Hexobarbital sodium is prepared by condensation of methyl(cyclohexen-1-yl)cyanoacetic ester with dicyanodiamide to 5-(cyclohexen- 1-yl)-5-methyl-2,6-diimino-3-cyanobarbituric acid, followed by methylation with dimethyl sulfate and hydrolysis with 25 % sulfuric acid .

HEXOBARBITAL Preparation Products And Raw materials

Raw materials

Preparation Products

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HEXOBARBITAL Suppliers

China 14 France 1 Germany 2 India 2 Switzerland 1 United Kingdom 5 United States 12 Global 37

56-29-1, HEXOBARBITALRelated Search:

DIHYDROTHYMINE 2-(1-CYCLOHEXENYL)ETHYLAMINE HEXOBARBITAL N,N,2,2-TETRAMETHYL-1,3-PROPANEDIAMINE N,N,2-TRIMETHYLPROPIONAMIDE 2,2,5-Trimethyl-4-hexenal dimethyl acetal CYCLOBARBITAL 2-ETHYL-2-HEXENAL,TRANS-2-ETHYL-2-HEXENAL TRANS-2-ETHYL-2-HEXENAL,2-ETHYL-2-HEXENAL 3-HEXENAL 2-PHENYL-5-METHYL-2-HEXENAL,5-METHYL-2-PHENYL-2-HEXENAL TRANS-2-HEXENAL,T2 HEXENAL 2-HEXENAL DIETHYL ACETAL,T2 HEXENAL DIETHYL ACETAL,TRANS-2-HEXENAL DIETHYL ACETAL trans-2-Hexenal propyleneglycol acetal 2-ISOPROPYL-5-METHYL-2-HEXENAL CIS-3-HEXENAL 2,2,5-Trimethyl-4-hexenal CIS-3-HEXENAL ACETAL

  • 5-[1-CYCLOHEXENYL]-1,5-DIMETHYLBARBITURIC ACID
  • LABOTEST-BB LT00244803
  • EVIPAL
  • HEXOBARBITAL
  • 1,5-Dimethyl-5-(1-cyclohexenyl)barbituric acid
  • 1,5-dimethyl-5-(1-cyclohexenyl)barbituricacid
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-cyclohexen-1-yl)-1,5-dimethyl-
  • Cyclopan
  • Dorico
  • Enhexymal
  • Esobarbitale
  • Evipan
  • Hexabarbital
  • Hexanastab oral
  • 5-(1-Cyclohexenyl)-1,5-dimethylbarbituric acid, Evipal
  • Toleran
  • 5-cyclohexen-1-yl-1,5-dimethyl-1,3-diazinane-2,4,6-trione
  • Hexobarbital CIII (500 mg)
  • Hexobarbital solution
  • 5-(1-Cyclohexen-1-yl)-1,5-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
  • 5-(1-Cyclohexen-1-yl)-1,5-dimethylbarbituric acid
  • 5-(1-cyclohexen-1-yl)-1,5-dimethyl-barbituricaci
  • 5-(1-cyclohexen-1-yl)-1,5-dimethylbarbituricacid
  • 5-(1-Cyclohexene-1-yl)-1,5-dimethylbarbituricacid
  • 5-(1-Cyclohexenyl-1)-1-methyl-5-methylbarbituric acid
  • 5-(1-cyclohexenyl-1)-1-methyl-5-methylbarbituricacid
  • 5-(Cyclohexen-1-yl)-1,5-dimethylbarbituric acid
  • 5-(Cyclohexen-1-yl)-1,5-dimethylbarbitursaeure
  • 5-(delta-1,2-cyclohexenyl)-5-methyl-N-methyl-barbitursaeure
  • hexanastaboral
  • Hexenal
  • Hexenal (barbiturate)
  • hexenal(barbiturate)
  • hexobarbital--deascheduleiiiitem
  • Hexobarbitone
  • Methexenyl
  • Methylhexabarbital
  • Methylhexabital
  • Narcosan
  • N-Methyl-5-cyclohexenyl-5-methylbarbituric acid
  • n-methyl-5-cyclohexenyl-5-methylbarbituricacid
  • Noctivane
  • Sombucaps
  • Sombulex
  • Somnalert
  • 5-(cyclohex-1-enyl)-1,5-dimethylbarbituric acid
  • hexobarbital methanol solution
  • Cyclohexemal
  • Hexobarbital (base and/or unspecified salts)
  • 6(1h,3h,5h)-pyrimidinetrione,5-(1-cyclohexen-1-yl)-1,5-dimethyl-4
  • Barbidorm
  • Barbituric acid, 5-(1-cyclohexen-1-yl)-1,5-dimethyl-
  • Citodon
  • Citopan
  • component of Percobarb
  • Cyclonal
  • Hexobarbital Solution, 100ppm
  • Hexobarbital CIII (1307003)