Ethyl methyldopate hydrochloride

Product Name: Ethyl methyldopate hydrochloride
CAS No.: 2508-79-4
Chemical Name: Ethyl methyldopate hydrochloride
Synonyms: METHYLDOPATE HCL;METHYLDOPAETHYLHCL;Ethyl ester hydrochloride;METHYLDOPATE HYDROCHLORIDE;QSRVZCCJDKYRRF-YDALLXLXSA-N;Aldomet Ester hydrochloride;methyldopa ethyl hydrochloride;Ethyl methyldopa hydrochloride;ethyl methyldopate hydrochloride;Methyldopate Hydrochloride (200 mg)
CBNumber: CB3746806
Molecular Formula: C12H17NO4.ClH
Formula Weight: 275.73
MOL File: 2508-79-4.mol

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Ethyl methyldopate hydrochloride Property

storage temp.: 2-8°C
form: crystalline powder

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Safety

HS Code: 2922504500

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0006819
Product name: METHYLDOPATE HYDROCHLORIDE
Purity: 95.00%
Packaging: 10MG
Price: $255.15
Updated: 2021/12/16

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Ethyl methyldopate hydrochloride Chemical Properties,Usage,Production

Uses

Ethyl methyldopate hydrochloride is Antihypertensive.

brand name

Aldomet (Merck).

General Description

Methyldopatehydrochloride, L-3-(3,4-dihydroxyphenyl)-2-methylalanineethyl ester hydrochloride (Aldomet ester hydrochloride), α-methyldopa, lowers blood pressure by inhibitingthe outflow of sympathetic vasoconstrictor impulses fromthe brain. Early studies had suggested that the hypotensiveaction of α-methyldopa was a result of the peripheral propertiesof the drug as a decarboxylase inhibitor or a falsetransmitter.

Clinical Use

Ethyl methyldopate hydrochloride is used as a step 2 agent and is recommendedfor patients with high blood pressure who are not responsiveto diuretic therapy alone. Ethyl methyldopate hydrochloride, suitable for oral use,is a zwitterion and is not soluble enough for parenteral use.The problem was solved by making the ester, leaving theamine free to form the water-soluble hydrochloride salt. It issupplied as a stable, buffered solution, protected with antioxidantsand chelating agents.

in vivo

Methyldopate is hydrolysed in vivo to methyldopa^[2].

IC 50

α adrenergic receptor

Ethyl methyldopate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl methyldopate hydrochloride Suppliers

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