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URSODEOXYCHOLIC-2,2,4,4-D4 ACID

Product Name
URSODEOXYCHOLIC-2,2,4,4-D4 ACID
CAS No.
347841-46-7
Chemical Name
URSODEOXYCHOLIC-2,2,4,4-D4 ACID
Synonyms
Ursodeoxycholic-d4 Acid;2H4]-Ursodeoxycholic Acid;URSODEOXYCHOLIC-2,2,4,4-D4 ACID;Urosodeoxycholic Acid Impurity 28;Ursodeoxycholic acid-[d4] (Solution);Ursodiol-d4 (Ursodeoxycholic Acid-d4);Ursodeoxycholic Acid-2,2,4,4-d4 (Major);Ursodeoxycholic Acid-d4 MaxSpec? Standard;*Dronedarone Impurity 37 ( Tributylamine);URSODEOXYCHOLICACID(2,2,4,4-D4) IN METHANOL
CBNumber
CB3755802
Molecular Formula
C24H40O4
Formula Weight
392.58
MOL File
347841-46-7.mol
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URSODEOXYCHOLIC-2,2,4,4-D4 ACID Property

storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly),
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21892
Product name
Ursodeoxycholic Acid-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
500μg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
21892
Product name
Ursodeoxycholic Acid-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
1mg
Price
$138
Updated
2024/03/01
Cayman Chemical
Product number
21892
Product name
Ursodeoxycholic Acid-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
5mg
Price
$575
Updated
2024/03/01
Medical Isotopes, Inc.
Product number
D2127
Product name
Ursodeoxycholic-2,2,4,4-d4acid
Packaging
5mg
Price
$590
Updated
2021/12/16
IsoSciences
Product number
13102
Product name
UrsodeoxycholicAcid-[d4]
Purity
≥95%
Packaging
50mg
Price
$288
Updated
2021/12/16
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URSODEOXYCHOLIC-2,2,4,4-D4 ACID Chemical Properties,Usage,Production

Description

Ursodeoxycholic acid-d4 (UDCA-d4) is intended for use as an internal standard for the quantification of UDCA (Item No. 15121) by GC- or LC-MS. UDCA is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.

Uses

Ursodeoxycholic Acid-d4 is a deuterated form of Ursodeoxcholic Acid (U850000), which is used as an anticholelithogenic. Ursodeoxcholic Acid is an epimer with Chenodiol with respect to the hydroxyl group at C7. Ursodeoxycholic Acid-d4 was used as an internal standard for rapid quantification of bile acids by liquid chromatography-tandem mass spectrometry.

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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URSODEOXYCHOLIC-2,2,4,4-D4 ACID Suppliers

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347841-46-7, URSODEOXYCHOLIC-2,2,4,4-D4 ACIDRelated Search:

URSODEOXYCHOLIC ACID ACYL-B-D-GLUCURONIDE Glycoursodeoxycholic Acid URSODEOXYCHOLIC ACID-24-13C Ursodeoxycholic acid Ursodeoxycholic Acid-d5 Ursodeoxycholic Acid Methyl Ester-d5 Taurolithocholic-d4 Acid (3α,5β,7β)- 3,7,22-Trihydroxycholan-24-oic Acid α-Muricholic Acid (3b,5b,7a,12a)-3,7,12-trihydroxy-Cholan-24-oic acid (4R)-4-[(3S,5S,7S,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(3S,5R,8S,9S,10S,12S,13R,14S)-1,3,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Ursodeocycholic Acid-[d4]-3-Sulfate Sodium Salt Ursodeocycholic Acid-3-Sulfate Sodium Salt (3a,5b,7a,12b)-3,7,12-trihydroxy-Cholan-24-oic acid 3,7-DIKETO-5BETA-CHOLAN-24-OIC ACID LITHOCHOLIC ACID 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid

  • URSODEOXYCHOLIC-2,2,4,4-D4 ACID
  • Ursodeoxycholic-d4 Acid
  • (4R)-4-[(3R,5R,7S,8R,9S,10S,13R,14S,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
  • (4R)-4-[(3R,5R,7S,8R,9S,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
  • Ursodiol-d4 (Ursodeoxycholic Acid-d4)
  • URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
  • Ursodeoxycholic acid-[d4] (Solution)
  • URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 95% CHEMICAL PURITY
  • Ursodeoxycholic Acid-d4 MaxSpec? Standard
  • Ursodeoxycholic Acid-2,2,4,4-d4 (Major)
  • (4R)-4-[(3R,5S,7S,8R,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
  • 2H4]-Ursodeoxycholic Acid
  • Urosodeoxycholic Acid Impurity 28
  • URSODEOXYCHOLICACID(2,2,4,4-D4) IN METHANOL
  • *Dronedarone Impurity 37 ( Tributylamine)
  • 347841-46-7
  • C24H36D4O4
  • Bile Acids - 13C & 2H