7-CHLOROQUINOLINE
- Product Name
- 7-CHLOROQUINOLINE
- CAS No.
- 612-61-3
- Chemical Name
- 7-CHLOROQUINOLINE
- Synonyms
- 7-CHLOROQUINOLINE;Quinoline, 7-chloro-;7-Chloro-1-azanaphthalene;7-Chloro-4-nitroquinoline;7-Chloroquinoline,97%,SS-5262
- CBNumber
- CB3758353
- Molecular Formula
- C9H6ClN
- Formula Weight
- 163.6
- MOL File
- 612-61-3.mol
7-CHLOROQUINOLINE Property
- Melting point:
- 31.5°C
- Boiling point:
- 268°C(lit.)
- Density
- 1.2158
- refractive index
- 1.6108 (estimate)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Acetone (Slightly), Chloroform (Slightly)
- pka
- 3.36±0.14(Predicted)
- form
- Solid
- color
- Tan
- λmax
- 319nm(EtOH aq.)(lit.)
- NIST Chemistry Reference
- 7-chloroquinoline(612-61-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- CDS014905
- Product name
- 7-chloroquinoline
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 100 mg
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- C3085
- Product name
- 7-Chloroquinoline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $223
- Updated
- 2025/07/31
- Product number
- C3085
- Product name
- 7-Chloroquinoline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $669
- Updated
- 2025/07/31
- Product number
- C381340
- Product name
- 7-Chloroquinoline
- Packaging
- 100mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- OR14909
- Product name
- 7-Chloroquinoline
- Packaging
- 5g
- Price
- $196
- Updated
- 2021/12/16
7-CHLOROQUINOLINE Chemical Properties,Usage,Production
Chemical Properties
light yellow powder
Uses
Chloroquinolines block antibiotic efflux pumps in antibiotic-resistant Enterobacter aerogenes isolates.
Synthesis
86-98-6
612-61-3
General Program 138: Synthesis of 7-chloroquinoline (Intermediate 573) 1. 4,7-Dichloroquinoline (10 g, 50 mmol) was dissolved in THF (100 ml) and degassed using N2 for 5 min. 2. PdCl2 (dppf) (1.2 g, 2 mmol), TMEDA (9.97 g, 86 mmol) and NaBH4 (3.24 g, 86 mmol) were added sequentially. 3. The reaction mixture was stirred at room temperature for 5 hours. 4. Upon completion of the reaction, brine (20 ml) was added dropwise followed by removal of solvent under vacuum. 5. The residue was dissolved in EtOAc (200 ml), dried by adding MgSO4 and then concentrated under vacuum. 6. The crude product was purified by column chromatography using heptane/EtOAc (4:1 to 1:1 gradient) as eluent to afford the title compound 7-chloroquinoline (5.4 g, 65% yield). MW: 163.61 HPLCMS (Method B): [m/z]: 163.90
References
[1] Tetrahedron Letters, 2010, vol. 51, # 12, p. 1562 - 1565
[2] Journal of Molecular Catalysis A: Chemical, 2014, vol. 393, p. 191 - 209
[3] Patent: US2012/214803, 2012, A1. Location in patent: Page/Page column 185
7-CHLOROQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
7-CHLOROQUINOLINE Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 7-CHLOROQUINOLINE manufacturers
- Product
- 7-CHLOROQUINOLINE 612-61-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-12
- Product
- 7-CHLOROQUINOLINE 612-61-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-28
- Product
- 7-CHLOROQUINOLINE 612-61-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-01