ChemicalBook > CAS DataBase List > 7-CHLOROQUINOLINE

7-CHLOROQUINOLINE

Product Name: 7-CHLOROQUINOLINE
CAS No.: 612-61-3
Chemical Name: 7-CHLOROQUINOLINE
Synonyms: 7-CHLOROQUINOLINE;Quinoline, 7-chloro-;7-Chloro-1-azanaphthalene;7-Chloro-4-nitroquinoline;7-Chloroquinoline,97%,SS-5262
CBNumber: CB3758353
Molecular Formula: C9H6ClN
Formula Weight: 163.6
MOL File: 612-61-3.mol

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7-CHLOROQUINOLINE Property

Melting point:: 31.5°C
Boiling point:: 268°C(lit.)
Density: 1.2158
refractive index: 1.6108 (estimate)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Acetone (Slightly), Chloroform (Slightly)
pka: 3.36±0.14(Predicted)
form: Solid
color: Tan
λmax: 319nm(EtOH aq.)(lit.)
NIST Chemistry Reference: 7-chloroquinoline(612-61-3)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS014905
Product name: 7-chloroquinoline
Purity: Aldrich<SUP>CPR</SUP>
Packaging: 100 mg
Price: $73.1
Updated: 2025/07/31

TCI Chemical

Product number: C3085
Product name: 7-Chloroquinoline
Purity: >98.0%(GC)
Packaging: 5g
Price: $223
Updated: 2025/07/31

TCI Chemical

Product number: C3085
Product name: 7-Chloroquinoline
Purity: >98.0%(GC)
Packaging: 25g
Price: $669
Updated: 2025/07/31

TRC

Product number: C381340
Product name: 7-Chloroquinoline
Packaging: 100mg
Price: $135
Updated: 2021/12/16

Apolloscientific

Product number: OR14909
Product name: 7-Chloroquinoline
Packaging: 1g
Price: $58
Updated: 2021/12/16

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7-CHLOROQUINOLINE Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Uses

Chloroquinolines block antibiotic efflux pumps in antibiotic-resistant Enterobacter aerogenes isolates.

Synthesis

86-98-6

612-61-3

General Program 138: Synthesis of 7-chloroquinoline (Intermediate 573) 1. 4,7-Dichloroquinoline (10 g, 50 mmol) was dissolved in THF (100 ml) and degassed using N2 for 5 min. 2. PdCl2 (dppf) (1.2 g, 2 mmol), TMEDA (9.97 g, 86 mmol) and NaBH4 (3.24 g, 86 mmol) were added sequentially. 3. The reaction mixture was stirred at room temperature for 5 hours. 4. Upon completion of the reaction, brine (20 ml) was added dropwise followed by removal of solvent under vacuum. 5. The residue was dissolved in EtOAc (200 ml), dried by adding MgSO4 and then concentrated under vacuum. 6. The crude product was purified by column chromatography using heptane/EtOAc (4:1 to 1:1 gradient) as eluent to afford the title compound 7-chloroquinoline (5.4 g, 65% yield). MW: 163.61 HPLCMS (Method B): [m/z]: 163.90

References

[1] Tetrahedron Letters, 2010, vol. 51, # 12, p. 1562 - 1565
[2] Journal of Molecular Catalysis A: Chemical, 2014, vol. 393, p. 191 - 209
[3] Patent: US2012/214803, 2012, A1. Location in patent: Page/Page column 185

7-CHLOROQUINOLINE Preparation Products And Raw materials

Raw materials

7-Aminoquinoline Sodium nitrite Diethyl ether Copper(I) chloride Hydrochloric acid Sodium hydroxide

Preparation Products

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7-CHLOROQUINOLINE Suppliers

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View Lastest Price from 7-CHLOROQUINOLINE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 7-CHLOROQUINOLINE 612-61-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

Shaanxi Dideu New Materials Co. Ltd

Product: 7-CHLOROQUINOLINE 612-61-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-28

Career Henan Chemical Co

Product: 7-CHLOROQUINOLINE 612-61-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

612-61-3, 7-CHLOROQUINOLINERelated Search:

6-Bromo-4-chloroquinoline ,97% 5-Chloroquinaldine QUINACRINE MUSTARD DIHYDROCHLORIDE 4-chloroquinoline-6-carboxylic acid 4-Chloroquinoline-3-boronic acid, 97% 7-chloroquinoline-4-carboxylic acid Mepacrine hydrochloride Quinclorac 7-Chloroquinolin-4-ol 5,7-Dichloro-8-hydroxyquinoline 7-Chloro-2-methylquinoline 5,7-Dichloro-8-hydroxyquinaldine Hydroxychloroquine sulfate 6,9-Dichloro-2-methoxyacridine 7-CHLORO-4-HYDROXY QUINOLINE-3-CARBOXYLIC ACID CHLOROQUINE 7-CHLORO-4-HYDRAZINOQUINOLINE Chloroquine diphosphate

7-CHLOROQUINOLINE

Quinoline, 7-chloro-

7-Chloro-4-nitroquinoline

7-Chloro-1-azanaphthalene

7-Chloroquinoline,97%,SS-5262

612-61-3

Aromatics Compounds

Aromatics

Heterocycles

Intermediates