2-Chloro-5-trifluoromethylbenzaldehyde
- Product Name
- 2-Chloro-5-trifluoromethylbenzaldehyde
- CAS No.
- 82386-89-8
- Chemical Name
- 2-Chloro-5-trifluoromethylbenzaldehyde
- Synonyms
- TIMTEC-BB SBB003466;2-Chloro-5-trifluoromethylb;4-Chloro-3-formylbenzotrifluoride;2-CHLORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE;2-Chloro-5-(trifluoromethyl)benzaldehyde98%;Benzaldehyde, 2-chloro-5-(trifluoromethyl)-;2-Chloro-5-(trifluoromethyl)benzaldehyde >2-Chloro-5-(trifluoromethyl)benzaldehyde, 97+%;2-Chloro-5-(trifluoroMethyl)benzaldehyde, 95+%;4-Chloro-3-formylbenzotrifluoride, 6-Chloro-alpha,alpha,alpha-trifluoro-m-tolualdehyde
- CBNumber
- CB3759178
- Molecular Formula
- C8H4ClF3O
- Formula Weight
- 208.57
- MOL File
- 82386-89-8.mol
2-Chloro-5-trifluoromethylbenzaldehyde Property
- Boiling point:
- 42-44 °C1.5 mm Hg(lit.)
- Density
- 1.435 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.488(lit.)
- Flash point:
- 193 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- clear liquid
- color
- White to Yellow to Green
- Specific Gravity
- 1.435
- Sensitive
- Air Sensitive
- InChIKey
- OZZOJJJYKYKBNH-UHFFFAOYSA-N
- CAS DataBase Reference
- 82386-89-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- RIDADR
- NA 1993 / PGIII
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29130000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 376825
- Product name
- 2-Chloro-5-(trifluoromethyl)benzaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $59
- Updated
- 2025/07/31
- Product number
- C2047
- Product name
- 2-Chloro-5-(trifluoromethyl)benzaldehyde
- Purity
- >95.0%(GC)
- Packaging
- 5g
- Price
- $62
- Updated
- 2025/07/31
- Product number
- C2047
- Product name
- 2-Chloro-5-(trifluoromethyl)benzaldehyde
- Purity
- >95.0%(GC)
- Packaging
- 25g
- Price
- $259
- Updated
- 2025/07/31
- Product number
- C596553
- Product name
- 2-Chloro-5-(trifluoromethyl)benzaldehyde
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 007805
- Product name
- 2-Chloro-5-(trifluoromethyl)benzaldehyde
- Purity
- 99%
- Packaging
- 1g
- Price
- $9
- Updated
- 2021/12/16
2-Chloro-5-trifluoromethylbenzaldehyde Chemical Properties,Usage,Production
Chemical Properties
Colorless liquid
Uses
2-Chloro-5-(trifluoromethyl)benzaldehyde may be used as reactant in the three-component reaction of 2-halogenated aromatic aldehydes, 1H-benzo[d]imidazol-5-amine and cyclohexane-1,3-diones to afford imidazoquinolinoacridinone derivatives. It may be used in the gas-phase chemical derivatization of poly(tetrafluoroethylene) and poly(ethylene terephthalate) using gas plasma.
Synthesis
64372-62-9
82386-89-8
General procedure for the synthesis of 2-chloro-5-trifluoromethylbenzaldehyde from 2-chloro-5-trifluoromethylbenzyl alcohol: 2-chloro-5-trifluoromethylbenzyl alcohol (5.0 mmol), copper acetate (Cu(OAc)2, 9.1 mg, 0.05 mmol), and 2,2,6,6-tetramethylpiperidinium-1-oxyl radical (TEMPO, 7.8 mg, 0.05 mmol ) in a solvent mixture of acetonitrile (CH3CN, 5 mL) and water (H2O, 10 mL) was stirred at room temperature for the reaction. The reaction process was monitored by thin-layer chromatography (TLC) and the eluent was petroleum ether/ethyl acetate (4:1). After completion of the reaction, dichloromethane (10 mL) was added to the reaction mixture for extraction. The organic phase was separated and the aqueous phase was extracted twice more with dichloromethane (10 mL x 2). All organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to obtain the crude product. The crude product was purified by column chromatography with the eluent of petroleum ether/ethyl acetate (10:1) to obtain the target product 2-chloro-5-trifluoromethylbenzaldehyde.
References
[1] Tetrahedron Letters, 2014, vol. 55, # 10, p. 1677 - 1681
[2] Collection of Czechoslovak Chemical Communications, 1982, vol. 47, # 3, p. 967 - 983
[3] Collection of Czechoslovak Chemical Communications, 1982, vol. 47, # 3, p. 967 - 983
[4] Collection of Czechoslovak Chemical Communications, 1982, vol. 47, # 3, p. 967 - 983
2-Chloro-5-trifluoromethylbenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-5-trifluoromethylbenzaldehyde Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 847-367-3680
- Fax
- 847-367-3681
- sales@arkpharminc.com
- Country
- United States
- ProdList
- 1670
- Advantage
- 56
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
View Lastest Price from 2-Chloro-5-trifluoromethylbenzaldehyde manufacturers
- Product
- 2-Chloro-5-trifluoromethylbenzaldehyde 82386-89-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-08
- Product
- 2-Chloro-5-trifluoromethylbenzaldehyde 82386-89-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15
- Product
- 2-Chloro-5-trifluoromethylbenzaldehyde 82386-89-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-06-28