L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE
- Product Name
- L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE
- CAS No.
- 67953-08-6
- Chemical Name
- L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE
- Synonyms
- H-GLU(PNA)-OH HCL;GPNA (hydrochloride);gamma-L-Glutamyl-4-nitroanilideHCl;7-bromo-6-oxocholestan-3-yl acetate;gamma-L-Glutamyl-p-nitroanilide HCl;L-GAMMA-GLUTAMYL-P-NITROANILIDE HYDROCHLORIDE;L-GAMMA-GLUTAMYL 4-NITROANILIDE HYDROCHLORIDE;GAMMA-L-GLUTAMYL-P-NITROANILIDE HYDROCHLORIDE;n-(4-nitrophenyl)-l-glutaminmonohydrochloride;N-(4-nitrophenyl)-L-glutamine monohydrochloride
- CBNumber
- CB3779866
- Molecular Formula
- C11H14ClN3O5
- Formula Weight
- 303.7
- MOL File
- 67953-08-6.mol
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Property
- storage temp.
- 2-8°C
- solubility
- Soluble in Water (up to 5 mg/ml).
- form
- solid
- color
- Off-white
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
- EPA Substance Registry System
- L-Glutamine, N-(4-nitrophenyl)-, monohydrochloride (67953-08-6)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- G6133
- Product name
- L-Glutamic acid γ-(p-nitroanilide) hydrochloride
- Purity
- γ-glutamyl transpeptidase substrate
- Packaging
- 1g
- Price
- $171
- Updated
- 2024/03/01
- Product number
- G6133
- Product name
- L-Glutamic acid γ-(p-nitroanilide) hydrochloride
- Purity
- γ-glutamyl transpeptidase substrate
- Packaging
- 5g
- Price
- $232.8
- Updated
- 2024/03/01
- Product number
- G6133
- Product name
- L-Glutamic acid γ-(p-nitroanilide) hydrochloride
- Purity
- γ-glutamyl transpeptidase substrate
- Packaging
- 25g
- Price
- $2030
- Updated
- 2024/03/01
- Product number
- G597108
- Product name
- L-Glutamic acid γ-(p-nitroanilide) hydrochloride
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 00412
- Product name
- L-Glutamicacidγ-(p-nitroanilide)hydrochloride,99%(HPLC)
- Purity
- 99%(HPLC)
- Packaging
- 1G
- Price
- $89.6
- Updated
- 2021/12/16
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Chemical Properties,Usage,Production
Description
L-γ-Glutamyl-p-nitroanilide (67953-08-6; GPNA) is a substrate for γ-glutamyl transpeptidase. GPNA is used for the determination of γ-glutamyl transpeptidase hydrolytic activity via spectrophotometric monitoring of p-nitroaniline released by the action of the enzyme on GPNA.1 GPNA has also been shown to be an inhibitor of glutamine uptake – solute-linked carrier family A1 member 5 (SLC1A5).2?Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that activates mTOR and is, thus, an interesting cancer chemotherapy target.3
Uses
L-Glutamic acid gamma-(p-nitroanilide) is used in methods of treating cancers having a deregulated NRF2/KEAP1 pathway.
References
1) Meister?et al. (1981),?γ-Glutamyl transpeptidase; Methods Enzymol.,?77?237 2) Esslinger?et al. (2005),?N-gamma-aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site; Bioorg. Med. Chem.,?13?1111 3) Nicklin?et al. (2012),?Bidirectional Transport of Amino Acid Regulates mTOR and Autophagy; Cell,?136?521
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Suppliers
- Tel
- +86 (21) 5811-6473 5811-6475
- Fax
- +86 (21) 6129-4103
- sales@koutingchina.com
- Country
- China
- ProdList
- 496
- Advantage
- 60
- Tel
- 020-39119399 18927568969
- Fax
- 020-39119999
- isunpharm@qq.com
- Country
- China
- ProdList
- 4428
- Advantage
- 55
- Tel
- +86 (21) 61124340
- Fax
- +86 (21) 6129-4103
- Country
- China
- ProdList
- 9767
- Advantage
- 58
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51471
- Advantage
- 80
- Tel
- 0510-83583050 13771062561
- Fax
- 0510-83583039
- willsun@peptide-search.com
- Country
- China
- ProdList
- 6716
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12308
- Advantage
- 58
- Tel
- 027-83778876 13667159345
- Fax
- 027-83778876
- 13667159345@163.com
- Country
- China
- ProdList
- 1967
- Advantage
- 55
- Tel
- 027-027-83778875 15807197853
- Fax
- 027-83991220
- 15807197853@163.com
- Country
- China
- ProdList
- 3982
- Advantage
- 58
- Tel
- 021-021-52271985 17721149837
- Fax
- +86 (21) 52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 19806
- Advantage
- 60
- Tel
- 025-58859352 18068836627
- Fax
- 02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 15085
- Advantage
- 58
- Tel
- 400-400-1332688 18019345275
- Fax
- 400-133-2688
- amy@rhawn.cn
- Country
- China
- ProdList
- 15503
- Advantage
- 58
- Tel
- 027-027-65522215 18163303831
- Fax
- -
- 360034463@qq.com
- Country
- China
- ProdList
- 994
- Advantage
- 58
- Tel
- 400-8210725 18016230971
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 24971
- Advantage
- 58
- Tel
- 0571-87213919
- Fax
- 0571-87213919
- eric@peptidego.com
- Country
- China
- ProdList
- 6526
- Advantage
- 58
- Tel
- 021-61263370 18901917034
- xingli@glbiochem.com
- Country
- China
- ProdList
- 5637
- Advantage
- 58
- Tel
- 021-61263377 15023907684
- Fax
- 021-61263399
- 15800684150@163.com
- Country
- China
- ProdList
- 8131
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19915
- Advantage
- 58
- Tel
- +86-021-61263370 +8615301650015
- wuqiuyan@glschina.com
- Country
- China
- ProdList
- 2975
- Advantage
- 58
- Tel
- 021-61263389 13524856427
- Fax
- WeChat630417570
- Joetang@glschina.com
- Country
- China
- ProdList
- 9668
- Advantage
- 58
- Tel
- 021-61263375 18168859245
- Country
- China
- ProdList
- 5958
- Advantage
- 58
- Tel
- 15061806929
- linda-fu@mimotopes.cn
- Country
- China
- ProdList
- 5849
- Advantage
- 58
- Tel
- 18221292452
- fannieliu@glschina.com
- Country
- China
- ProdList
- 6799
- Advantage
- 58
- Tel
- 18217475093
- 1615396342@qq.com
- Country
- China
- ProdList
- 4309
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49323
- Advantage
- 58
- Tel
- +86-0371-86658258 15093356674;
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29826
- Advantage
- 58
- Tel
- 18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 3059
- Advantage
- 58
- Tel
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29778
- Advantage
- 58
- Tel
- 400-1647117 15221909166
- product02@bidepharm.com
- Country
- China
- ProdList
- 63720
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24017
- Advantage
- 58
- Tel
- 0571-87213919 17306812703
- 3007955328@qq.com
- Country
- China
- ProdList
- 6213
- Advantage
- 58
- Tel
- 0371-53370800 18037197114
- 2853031799@qq.com
- Country
- China
- ProdList
- 10007
- Advantage
- 58
- Tel
- 0512-65118909 15162312715
- sales@szzxbio.com
- Country
- China
- ProdList
- 2988
- Advantage
- 58
- Tel
- 18014399201
- sales@chemlab-tachizaki.com
- Country
- China
- ProdList
- 2495
- Advantage
- 58
- Tel
- 021-58000709 15900491054
- info@scrbio.com
- Country
- China
- ProdList
- 9267
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50751
- Advantage
- 58
- Tel
- 19821570922
- angela@labgogo.com
- Country
- China
- ProdList
- 9901
- Advantage
- 58
- Tel
- 021-54306202 18917919676
- info@hanhongsci.com
- Country
- China
- ProdList
- 29990
- Advantage
- 58
- Tel
- +86-18521732826
- market@aladdin-e.com
- Country
- China
- ProdList
- 48467
- Advantage
- 58
- Tel
- +86-852-30606658
- market18@leapchem.com
- Country
- China
- ProdList
- 43348
- Advantage
- 58
- Tel
- +undefined18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 3136
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@zzsrm.com
- Country
- CHINA
- ProdList
- 6846
- Advantage
- 58
- Tel
- --
- Fax
- --
- weibochem@163.com
- Country
- China
- ProdList
- 6187
- Advantage
- 67
View Lastest Price from L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE manufacturers
- Product
- L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE 67953-08-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100 kg
- Release date
- 2020-01-10