MURISTERONE A

Product Name: MURISTERONE A
CAS No.: 38778-30-2
Chemical Name: MURISTERONE A
Synonyms: MURA;Muristerone;MURISTERONE A;Ecdysonic sterol;MURISTERONE A(P);MURISTERONE A USP/EP/BP;MURISTERONE A, IPOMOEA SPP;5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE;2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE;2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
CBNumber: CB3781616
Molecular Formula: C27H44O8
Formula Weight: 496.63
MOL File: 38778-30-2.mol

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MURISTERONE A Property

Boiling point:: 707.2±60.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: Soluble in DMSO
form: solid
pka: 11.78±0.70(Predicted)
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 11741
Product name: Muristerone A
Purity: ≥95%
Packaging: 250μg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 11741
Product name: Muristerone A
Purity: ≥95%
Packaging: 1mg
Price: $155
Updated: 2024/03/01

TRC

Product number: M732780
Product name: MuristeroneA
Packaging: 1mg
Price: $205
Updated: 2021/12/16

Usbiological

Product number: 045051
Product name: Muristerone A
Packaging: 250ug
Price: $289
Updated: 2021/12/16

Usbiological

Product number: 255918
Product name: Muristerone A
Packaging: 1mg
Price: $480
Updated: 2021/12/16

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MURISTERONE A Chemical Properties,Usage,Production

Description

Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (K_d = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.

Uses

Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.

Biological Activity

Ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.

storage

+4°C

MURISTERONE A Preparation Products And Raw materials

Raw materials

Preparation Products

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MURISTERONE A Suppliers

China 53 Japan 1 Switzerland 3 United Kingdom 10 United States 12 Global 79

EMMX Biotechnology LLC

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TargetMol Chemicals Inc.

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Aladdin Scientific

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Cayman Chemical Company

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United States Biological

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EMD Biosciences, Inc.

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38778-30-2, MURISTERONE ARelated Search:

3,5-Dimethyl-2-cyclohexen-1-one Celery ketone L-Menthol Isophorone 1-HYDROXY-3-CYCLOHEXENE 2-Octyl-1-dodecanol cis-9-Tricosene RICINOLEYL ALCOHOL 2-Methyl-3-buten-2-ol 3,7-DIMETHYL-1-OCTEN-3-OL 1-Decen-3-ol 5-METHYL-2-HEPTEN-4-ONE Dihydromyrcenol cis-1,2-Cyclohexanediol (-)-NEOMENTHOL 1-ACETYLCYCLOHEXANOL MURISTERONE A 2-HEPTANONE，5-(HYDROXYMETHYL)

2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE

2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTAHYDROXY-5BETA,7-CHOLESTEN-6-ONE

2BETA,3BETA,5BETA,11ALPHA,14ALPHA,20R,22R-HEPTAHYDROXYCHOLEST-7-EN-6-ONE

5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE

5BETA,7-CHOLESTENE-2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTOL-6-ONE

MurA, 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one

(22R)-2β,3β,5,11α,14,20,22-Heptahydroxy-5β-cholest-7-en-6-one

Ecdysonic sterol

Muristerone

Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2beta,3beta,5beta,11alpha,22R)-

(2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-Heptahydroxycholest-7-en-6-one

MURISTERONE A(P)

(2beta,3beta,5beta,11alpha,22R)-2,3,5,11,14,20,22-Heptahydroxy-cholest-7-en-6-one

MURISTERONE A

MURISTERONE A, IPOMOEA SPP

MURA

2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one

MURISTERONE A USP/EP/BP

Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2β,3β,5β,11α,22R)-

38778-30-2

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