TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE

Product Name: TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE
CAS No.: 258515-65-0
Chemical Name: TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE
Synonyms: tert-butyl 7-bromo-1,2,3,4-tetrahydr;2-Boc-7-bromo-3,4-dihydro-1H-isoquinoline;2-Boc-7-bromo-1,2,3,4-tetrahydroisoquinoline;N-Boc-7-BroMo-1,2,3,4-Tetrahydroisoquinoline;ert-butyl7-bromo-3,4-dihydro-1H-isoquinoline-2-carboxylate;tert-butyl 7-bromo-3,4-dihydro-1H-isoquinoline-2-carboxylate;TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE;tert-butyl 7-bromo-1,2,3,4-tetrahydroisoquinoline-2-carboxylate; METHTERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE;7-BroMo-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester
CBNumber: CB3798799
Molecular Formula: C14H18BrNO2
Formula Weight: 312.2
MOL File: Mol file

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TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE Property

Boiling point:: 374.2±42.0 °C(Predicted)
Density: 1.353±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -1.55±0.20(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C14H18BrNO2/c1-14(2,3)18-13(17)16-7-6-10-4-5-12(15)8-11(10)9-16/h4-5,8H,6-7,9H2,1-3H3
InChIKey: PWPKRLMPHNRWHK-UHFFFAOYSA-N
SMILES: C1C2=C(C=CC(Br)=C2)CCN1C(OC(C)(C)C)=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B694510
Product name: tert-Butyl7-Bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B694510
Product name: tert-Butyl7-Bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: B694510
Product name: tert-Butyl7-Bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate
Packaging: 500mg
Price: $155
Updated: 2021/12/16

Ark Pharm

Product number: P000205836
Product name: tert-Butyl 7-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate
Purity: 97%
Packaging: 5g
Price: $114
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144123
Product name: tert-Butyl 7-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate
Packaging: 500mg
Price: $130
Updated: 2021/12/16

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TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

17680-55-6

24424-99-5

258515-65-0

To a mixed solution of 7-bromo-1,2,3,4-tetrahydroisoquinoline (1 g, 4.71 mmol) and sodium carbonate (1 g, 9.4 mmol) in tetrahydrofuran/water (16 mL/6 mL) was added di-tert-butyl dicarbonate (1.51 mL, 7.06 mmol). The reaction mixture was stirred at room temperature overnight. After the reaction was completed, the reaction mixture was diluted with water (50 mL) and extracted with ethyl acetate (50 mL x 3). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford tert-butyl 7-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate as a colorless oil (1.46 g, 100% yield).

References

[1] Patent: WO2014/89324, 2014, A1. Location in patent: Paragraph 0240
[2] Patent: CN104016979, 2017, B. Location in patent: Paragraph 0620; 0621
[3] Patent: US2010/240671, 2010, A1. Location in patent: Page/Page column 58
[4] Patent: WO2017/1853, 2017, A1. Location in patent: Page/Page column 42-43
[5] Patent: CN105524045, 2016, A. Location in patent: Paragraph 0274; 0275; 0276

TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE Suppliers

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ITIC MEDCHEM(SUZHOU) CO.,LTD.

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View Lastest Price from TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 258515-65-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-04

Career Henan Chemical Co

Product: METHTERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 258515-65-0
Price: US $1.00/KG
Min. Order: 1g
Purity: 98%
Supply Ability: 200kgs
Release date: 2020-01-09

258515-65-0, TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATERelated Search:

7-bromo-4H-chromen-4-one 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine 7-BROMO-1H-INDOLE-3-CARBALDEHYDE 6-Tributylstannyl[1,2,4]triazolo[1,5-a]pyridine 7-BROMO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 7-BroMo-3-MethyliMidazo[1,5-a]pyridine 7-Bromo[1,2,4]triazolo[1,5-a]pyridine [[(6-BROMO)-2-PYRIDINYL]METHYL]-CARBAMIC ACID, 1,1-DIMETHYLETHYL ESTER TERT-BUTYL 8-HYDROXY-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE tert-butyl N-[(2-methylpyridin-3-yl)methyl]carbamate tert-butyl N-[(2-chloropyridin-4-yl)Methyl]carbaMate tert-Butyl 7-broMo-3,4-dihydroquinoline-1(2H)-carboxylate 2(1H)-Isoquinolinecarboxylic acid, 7-bromo-3,4-dihydro-6-methyl-, 1,1-dimethylethyl ester tert-butyl 6-hydroxy-5-methyl-3,4-dihydroisoquinoline-2(1H)-carboxylate tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate

N-Boc-7-BroMo-1,2,3,4-Tetrahydroisoquinoline

TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE

7-BroMo-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester

2-Boc-7-bromo-3,4-dihydro-1H-isoquinoline

tert-butyl 7-bromo-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

tert-butyl 7-bromo-1,2,3,4-tetrahydr

2-Boc-7-bromo-1,2,3,4-tetrahydroisoquinoline

METHTERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE

ert-butyl7-bromo-3,4-dihydro-1H-isoquinoline-2-carboxylate

TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE ISO 9001：2015 REACH

tert-butyl 7-bromo-3,4-dihydro-1H-isoquinoline-2-carboxylate

258515-65-0